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MGI:Cul3

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Contents

Species (Taxon ID) Mus musculus (house mouse) (taxon:10090)
Gene Name(s) Cul3
Protein Name(s) cullin 3,
External Links
MGI MGI:1347360

Annotations

Qualifier GO ID GO term name Reference Evidence Code with/from Aspect Notes Status
GO:0000090

mitotic anaphase

MGI:MGI:4834177

ISO: Inferred from Sequence Orthology

UniProtKB:Q13618

P

From MGI

GO:0000902

cell morphogenesis

MGI:MGI:1345775
PMID:10500095[1]

IMP: Inferred from Mutant Phenotype

MGI:MGI:2651546

P

From MGI

GO:0000910

cytokinesis

MGI:MGI:4834177

ISO: Inferred from Sequence Orthology

UniProtKB:Q13618

P

From MGI

GO:0001701

in utero embryonic development

MGI:MGI:1345775
PMID:10500095[1]

IMP: Inferred from Mutant Phenotype

MGI:MGI:2651546

P

From MGI

GO:0001831

trophectodermal cellular morphogenesis

MGI:MGI:1345775
PMID:10500095[1]

IMP: Inferred from Mutant Phenotype

MGI:MGI:2651546

P

From MGI

GO:0005634

nucleus

MGI:MGI:1345775
PMID:10500095[1]

IDA: Inferred from Direct Assay

C

From MGI

GO:0005794

Golgi apparatus

MGI:MGI:1345775
PMID:10500095[1]

IDA: Inferred from Direct Assay

C

From MGI

GO:0005827

polar microtubule

MGI:MGI:4834177

ISO: Inferred from Sequence Orthology

UniProtKB:Q13618

C

From MGI

GO:0006511

ubiquitin-dependent protein catabolic process

MGI:MGI:2152098

IEA: Inferred from Electronic Annotation

InterPro:IPR016157
InterPro:IPR016158
InterPro:IPR001373
InterPro:IPR019559

P

From MGI

GO:0006513

protein monoubiquitination

MGI:MGI:4834177

ISO: Inferred from Sequence Orthology

UniProtKB:Q13618

P

From MGI

GO:0006810

transport

MGI:MGI:1354194

IEA: Inferred from Electronic Annotation

UniProtKB-KW:KW-0813

P

From MGI

GO:0006888

ER to Golgi vesicle-mediated transport

MGI:MGI:4834177

ISO: Inferred from Sequence Orthology

UniProtKB:Q13618

P

From MGI

GO:0007229

integrin-mediated signaling pathway

MGI:MGI:5312166
PMID:22358839[2]

IMP: Inferred from Mutant Phenotype

P

From MGI

GO:0007369

gastrulation

MGI:MGI:1345775
PMID:10500095[1]

IMP: Inferred from Mutant Phenotype

MGI:MGI:2651546

P

From MGI

GO:0008054

cyclin catabolic process

MGI:MGI:1345775
PMID:10500095[1]

ISS: Inferred from Sequence or Structural Similarity

UniProtKB:Q13618

P

From MGI

GO:0016055

Wnt receptor signaling pathway

MGI:MGI:3820325
PMID:19056892[3]

IDA: Inferred from Direct Assay

P

From MGI

GO:0016192

vesicle-mediated transport

MGI:MGI:1354194

IEA: Inferred from Electronic Annotation

UniProtKB-KW:KW-0931

P

From MGI

GO:0016477

cell migration

MGI:MGI:4834177

ISO: Inferred from Sequence Orthology

UniProtKB:Q13618

P

From MGI

GO:0016567

protein ubiquitination

MGI:MGI:4834177

ISO: Inferred from Sequence Orthology

UniProtKB:Q13618

P

From MGI

GO:0017145

stem cell division

MGI:MGI:5312166
PMID:22358839[2]

IMP: Inferred from Mutant Phenotype

P

From MGI

GO:0030332

cyclin binding

MGI:MGI:1345775
PMID:10500095[1]

IPI: Inferred from Physical Interaction

UniProtKB:Q61457

F

From MGI

GO:0031461

cullin-RING ubiquitin ligase complex

MGI:MGI:2152098

IEA: Inferred from Electronic Annotation

InterPro:IPR016157
InterPro:IPR016158
InterPro:IPR001373
InterPro:IPR019559

C

From MGI

GO:0031463

Cul3-RING ubiquitin ligase complex

MGI:MGI:4834177

ISO: Inferred from Sequence Orthology

UniProtKB:Q13618

C

From MGI

GO:0031625

ubiquitin protein ligase binding

MGI:MGI:2152098

IEA: Inferred from Electronic Annotation

InterPro:IPR016157
InterPro:IPR016158
InterPro:IPR001373
InterPro:IPR019559

F

From MGI

GO:0035024

negative regulation of Rho protein signal transduction

MGI:MGI:4834177

ISO: Inferred from Sequence Orthology

UniProtKB:Q13618

P

From MGI

GO:0040016

embryonic cleavage

MGI:MGI:5312166
PMID:22358839[2]

IMP: Inferred from Mutant Phenotype

P

From MGI

GO:0043149

stress fiber assembly

MGI:MGI:4834177

ISO: Inferred from Sequence Orthology

UniProtKB:Q13618

P

From MGI

GO:0043161

proteasomal ubiquitin-dependent protein catabolic process

MGI:MGI:4834177

ISO: Inferred from Sequence Orthology

UniProtKB:Q13618

P

From MGI

GO:0048208

COPII vesicle coating

MGI:MGI:4834177

ISO: Inferred from Sequence Orthology

UniProtKB:Q13618

P

From MGI

GO:0051322

anaphase

MGI:MGI:4834177

ISO: Inferred from Sequence Orthology

UniProtKB:Q13618

P

From MGI


Notes

References

See Help:References for how to manage references in GONUTS.
  1. 1.0 1.1 1.2 1.3 1.4 1.5 1.6 1.7 Singer JD et al. (1999) Cullin-3 targets cyclin E for ubiquitination and controls S phase in mammalian cells. Genes Dev 13: 2375-87 PubMed GONUTS page
  2. 2.0 2.1 2.2 Jin L et al. (2012) Ubiquitin-dependent regulation of COPII coat size and function. Nature 482: 495-500 PubMed GONUTS page
  3. Miranda-Carboni GA et al. (2008) A functional link between Wnt signaling and SKP2-independent p27 turnover in mammary tumors. Genes Dev 22: 3121-34 PubMed GONUTS page
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