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MGI:Cttn
Contents |
| Species (Taxon ID) | Mus musculus (house mouse) (taxon:10090) | |
| Gene Name(s) | Cttn ( synonyms: Ems1 ) | |
| Protein Name(s) | cortactin, | |
| External Links | ||
| MGI | MGI:99695 | |
Annotations
| Qualifier | GO ID | GO term name | Reference | Evidence Code | with/from | Aspect | Notes | Status |
|---|---|---|---|---|---|---|---|---|
| GO:0001726 |
ruffle |
MGI:MGI:1353214 |
IDA: Inferred from Direct Assay |
C |
From MGI |
|||
| GO:0001726 |
ruffle |
MGI:MGI:2671745 |
IDA: Inferred from Direct Assay |
C |
From MGI |
|||
| GO:0005515 |
protein binding |
MGI:MGI:2671745 |
IPI: Inferred from Physical Interaction |
F |
From MGI |
|||
| GO:0005515 |
protein binding |
MGI:MGI:4419086 |
IPI: Inferred from Physical Interaction |
F |
From MGI |
|||
| GO:0005737 |
cytoplasm |
MGI:MGI:2671745 |
IDA: Inferred from Direct Assay |
C |
From MGI |
|||
| GO:0005737 |
cytoplasm |
MGI:MGI:4834177 |
ISO: Inferred from Sequence Orthology |
C |
From MGI |
|||
| GO:0005856 |
cytoskeleton |
MGI:MGI:1354194 |
IEA: Inferred from Electronic Annotation |
UniProtKB-KW:KW-0206 |
C |
From MGI |
||
| GO:0005938 |
cell cortex |
MGI:MGI:2671745 |
IDA: Inferred from Direct Assay |
C |
From MGI |
|||
| GO:0006898 |
receptor-mediated endocytosis |
MGI:MGI:4417868 |
ISO: Inferred from Sequence Orthology |
P |
From MGI |
|||
| GO:0030027 |
lamellipodium |
MGI:MGI:2668778 |
IDA: Inferred from Direct Assay |
C |
From MGI |
|||
| GO:0030027 |
lamellipodium |
MGI:MGI:2671745 |
IDA: Inferred from Direct Assay |
C |
From MGI |
|||
| GO:0030027 |
lamellipodium |
MGI:MGI:4834177 |
ISO: Inferred from Sequence Orthology |
C |
From MGI |
|||
| GO:0042995 |
cell projection |
MGI:MGI:1354194 |
IEA: Inferred from Electronic Annotation |
UniProtKB-KW:KW-0966 |
C |
From MGI |
||
| GO:0070064 |
proline-rich region binding |
MGI:MGI:4417868 |
ISO: Inferred from Sequence Orthology |
F |
From MGI |
| ||
| edit table |
Notes
References
See Help:References for how to manage references in GONUTS.
- ↑ Kessels MM et al. (2000) Association of mouse actin-binding protein 1 (mAbp1/SH3P7), an Src kinase target, with dynamic regions of the cortical actin cytoskeleton in response to Rac1 activation. Mol Biol Cell 11: 393-412 PubMed GONUTS page
- ↑ 2.0 2.1 2.2 2.3 2.4 Hou P et al. (2003) Fgd1, the Cdc42 GEF responsible for Faciogenital Dysplasia, directly interacts with cortactin and mAbp1 to modulate cell shape. Hum Mol Genet 12: 1981-93 PubMed GONUTS page
- ↑ Kinley AW et al. (2003) Cortactin interacts with WIP in regulating Arp2/3 activation and membrane protrusion. Curr Biol 13: 384-93 PubMed GONUTS page
- ↑ Yan C et al. (2003) WAVE2 deficiency reveals distinct roles in embryogenesis and Rac-mediated actin-based motility. EMBO J 22: 3602-12 PubMed GONUTS page
