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MGI:Ctnnbip1
Contents |
| Species (Taxon ID) | Mus musculus (house mouse) (taxon:10090) | |
| Gene Name(s) | Ctnnbip1 ( synonyms: Catnbip1, ICAT ) | |
| Protein Name(s) | catenin beta interacting protein 1, | |
| External Links | ||
| MGI | MGI:1915756 | |
Annotations
| Qualifier | GO ID | GO term name | Reference | Evidence Code | with/from | Aspect | Notes | Status |
|---|---|---|---|---|---|---|---|---|
| GO:0000122 |
negative regulation of transcription from RNA polymerase II promoter |
MGI:MGI:3690195 |
IDA: Inferred from Direct Assay |
P |
From MGI |
|||
| GO:0000122 |
negative regulation of transcription from RNA polymerase II promoter |
MGI:MGI:4821083 |
IDA: Inferred from Direct Assay |
P |
From MGI |
|||
| GO:0001658 |
branching involved in ureteric bud morphogenesis |
MGI:MGI:3757813 |
IMP: Inferred from Mutant Phenotype |
MGI:MGI:3045424 |
P |
From MGI |
||
| GO:0002528 |
regulation of vascular permeability involved in acute inflammatory response |
MGI:MGI:4834177 |
ISO: Inferred from Sequence Orthology |
P |
From MGI |
|||
| GO:0005515 |
protein binding |
MGI:MGI:2158579 |
IPI: Inferred from Physical Interaction |
F |
From MGI |
|||
| GO:0005634 |
nucleus |
MGI:MGI:2158579 |
TAS: Traceable Author Statement |
C |
From MGI |
|||
| GO:0005634 |
nucleus |
MGI:MGI:4834177 |
ISO: Inferred from Sequence Orthology |
C |
From MGI |
|||
| GO:0005737 |
cytoplasm |
MGI:MGI:2158579 |
TAS: Traceable Author Statement |
C |
From MGI |
|||
| GO:0005737 |
cytoplasm |
MGI:MGI:4834177 |
ISO: Inferred from Sequence Orthology |
C |
From MGI |
|||
| GO:0005829 |
cytosol |
MGI:MGI:4834177 |
ISO: Inferred from Sequence Orthology |
C |
From MGI |
|||
| GO:0008013 |
beta-catenin binding |
MGI:MGI:2677113 |
IPI: Inferred from Physical Interaction |
F |
From MGI |
|||
| GO:0008013 |
beta-catenin binding |
MGI:MGI:4818257 |
IPI: Inferred from Physical Interaction |
F |
From MGI |
|||
| GO:0008013 |
beta-catenin binding |
MGI:MGI:4834177 |
ISO: Inferred from Sequence Orthology |
F |
From MGI |
|||
| GO:0009952 |
anterior/posterior pattern specification |
MGI:MGI:3044441 |
IMP: Inferred from Mutant Phenotype |
MGI:MGI:3045424 |
P |
From MGI |
||
| GO:0016055 |
Wnt receptor signaling pathway |
MGI:MGI:2158579 |
IPI: Inferred from Physical Interaction |
P |
From MGI |
|||
| GO:0030178 |
negative regulation of Wnt receptor signaling pathway |
MGI:MGI:3044441 |
IDA: Inferred from Direct Assay |
P |
From MGI |
|||
| GO:0031333 |
negative regulation of protein complex assembly |
MGI:MGI:4821083 |
IDA: Inferred from Direct Assay |
P |
From MGI |
|||
| GO:0032091 |
negative regulation of protein binding |
MGI:MGI:4834177 |
ISO: Inferred from Sequence Orthology |
P |
From MGI |
|||
| GO:0034747 |
Axin-APC-beta-catenin-GSK3B complex |
MGI:MGI:4834177 |
ISO: Inferred from Sequence Orthology |
C |
From MGI |
|||
| GO:0043392 |
negative regulation of DNA binding |
MGI:MGI:4821083 |
IDA: Inferred from Direct Assay |
P |
From MGI |
|||
| GO:0043433 |
negative regulation of sequence-specific DNA binding transcription factor activity |
MGI:MGI:4821083 |
IDA: Inferred from Direct Assay |
P |
From MGI |
|||
| GO:0043433 |
negative regulation of sequence-specific DNA binding transcription factor activity |
MGI:MGI:4834177 |
ISO: Inferred from Sequence Orthology |
P |
From MGI |
|||
| GO:0045657 |
positive regulation of monocyte differentiation |
MGI:MGI:4834177 |
ISO: Inferred from Sequence Orthology |
P |
From MGI |
|||
| GO:0045669 |
positive regulation of osteoblast differentiation |
MGI:MGI:4834177 |
ISO: Inferred from Sequence Orthology |
P |
From MGI |
|||
| GO:0048662 |
negative regulation of smooth muscle cell proliferation |
MGI:MGI:4821071 |
IMP: Inferred from Mutant Phenotype |
P |
From MGI |
|||
| GO:0060633 |
negative regulation of transcription initiation from RNA polymerase II promoter |
MGI:MGI:4821083 |
IDA: Inferred from Direct Assay |
P |
From MGI |
|||
| GO:0070016 |
armadillo repeat domain binding |
MGI:MGI:4834177 |
ISO: Inferred from Sequence Orthology |
F |
From MGI |
|||
| GO:0072201 |
negative regulation of mesenchymal cell proliferation |
MGI:MGI:4834177 |
ISO: Inferred from Sequence Orthology |
P |
From MGI |
| ||
| edit table |
Notes
References
See Help:References for how to manage references in GONUTS.
- ↑ Olson LE et al. (2006) Homeodomain-mediated beta-catenin-dependent switching events dictate cell-lineage determination. Cell 125: 593-605 PubMed GONUTS page
- ↑ 2.0 2.1 2.2 2.3 2.4 Tutter AV et al. (2001) Chromatin-specific regulation of LEF-1-beta-catenin transcription activation and inhibition in vitro. Genes Dev 15: 3342-54 PubMed GONUTS page
- ↑ Hasegawa Y et al. (2007) Loss of ICAT gene function leads to arrest of ureteric bud branching and renal agenesis. Biochem Biophys Res Commun 362: 988-94 PubMed GONUTS page
- ↑ 4.0 4.1 4.2 4.3 Tago K et al. (2000) Inhibition of Wnt signaling by ICAT, a novel beta-catenin-interacting protein. Genes Dev 14: 1741-9 PubMed GONUTS page
- ↑ Kanamori M et al. (2003) The PDZ protein tax-interacting protein-1 inhibits beta-catenin transcriptional activity and growth of colorectal cancer cells. J Biol Chem 278: 38758-64 PubMed GONUTS page
- ↑ Graham TA et al. (2002) The crystal structure of the beta-catenin/ICAT complex reveals the inhibitory mechanism of ICAT. Mol Cell 10: 563-71 PubMed GONUTS page
- ↑ 7.0 7.1 Satoh K et al. (2004) Anteriorization of neural fate by inhibitor of beta-catenin and T cell factor (ICAT), a negative regulator of Wnt signaling. Proc Natl Acad Sci U S A 101: 8017-21 PubMed GONUTS page
- ↑ Quasnichka H et al. (2006) Regulation of smooth muscle cell proliferation by beta-catenin/T-cell factor signaling involves modulation of cyclin D1 and p21 expression. Circ Res 99: 1329-37 PubMed GONUTS page
