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MGI:Cthrc1

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Contents

Species (Taxon ID) Mus musculus (house mouse) (taxon:10090)
Gene Name(s) Cthrc1
Protein Name(s) collagen triple helix repeat containing 1,
External Links
MGI MGI:1915838

Annotations

Qualifier GO ID GO term name Reference Evidence Code with/from Aspect Notes Status
GO:0005109

frizzled binding

MGI:MGI:3814781
PMID:18606138[1]

IPI: Inferred from Physical Interaction

UniProtKB:Q61086
UniProtKB:Q9EQD0
UniProtKB:Q61089

F

From MGI

GO:0005515

protein binding

MGI:MGI:3814781
PMID:18606138[1]

IPI: Inferred from Physical Interaction

UniProtKB:Q9Z138

F

From MGI

GO:0005615

extracellular space

MGI:MGI:2154458

ISO: Inferred from Sequence Orthology

UniProtKB:Q96CG8

C

From MGI

GO:0005737

cytoplasm

MGI:MGI:4452466
PMID:18467647[2]

IDA: Inferred from Direct Assay

C

From MGI

GO:0016477

cell migration

MGI:MGI:2154458

ISO: Inferred from Sequence Orthology

UniProtKB:Q8CG08

P

From MGI

GO:0016477

cell migration

MGI:MGI:4417868

ISO: Inferred from Sequence Orthology

NCBI:NP_758836

P

From MGI

GO:0017147

Wnt-protein binding

MGI:MGI:3814781
PMID:18606138[1]

IPI: Inferred from Physical Interaction

UniProtKB:P27467
UniProtKB:P22725
UniProtKB:P48615

F

From MGI

GO:0031012

extracellular matrix

MGI:MGI:2154458

ISO: Inferred from Sequence Orthology

UniProtKB:Q8CG08

C

From MGI

GO:0032092

positive regulation of protein binding

MGI:MGI:3814781
PMID:18606138[1]

IDA: Inferred from Direct Assay

P

From MGI

GO:0033690

positive regulation of osteoblast proliferation

MGI:MGI:3829514
PMID:18779865[3]

IMP: Inferred from Mutant Phenotype

MGI:MGI:3830252

P

From MGI

GO:0043932

ossification involved in bone remodeling

MGI:MGI:3829514
PMID:18779865[3]

IMP: Inferred from Mutant Phenotype

MGI:MGI:3830252

P

From MGI

GO:0045669

positive regulation of osteoblast differentiation

MGI:MGI:3829514
PMID:18779865[3]

IMP: Inferred from Mutant Phenotype

MGI:MGI:3830252

P

From MGI

GO:0060071

Wnt receptor signaling pathway, planar cell polarity pathway

MGI:MGI:3814781
PMID:18606138[1]

IMP: Inferred from Mutant Phenotype

MGI:MGI:3815067

P

From MGI

GO:0060122

inner ear receptor stereocilium organization

MGI:MGI:3814781
PMID:18606138[1]

IGI: Inferred from Genetic Interaction

MGI:MGI:1915838

P

From MGI

GO:0090090

negative regulation of canonical Wnt receptor signaling pathway

MGI:MGI:3814781
PMID:18606138[1]

IDA: Inferred from Direct Assay

P

From MGI

GO:0090103

cochlea morphogenesis

MGI:MGI:3814781
PMID:18606138[1]

IGI: Inferred from Genetic Interaction

MGI:MGI:1915838

P

From MGI

GO:0090177

establishment of planar polarity involved in neural tube closure

MGI:MGI:3814781
PMID:18606138[1]

IGI: Inferred from Genetic Interaction

MGI:MGI:1915838

P

From MGI


Notes

References

See Help:References for how to manage references in GONUTS.
  1. 1.0 1.1 1.2 1.3 1.4 1.5 1.6 1.7 1.8 Yamamoto S et al. (2008) Cthrc1 selectively activates the planar cell polarity pathway of Wnt signaling by stabilizing the Wnt-receptor complex. Dev Cell 15: 23-36 PubMed GONUTS page
  2. Leclair RJ et al. (2008) Intracellular localization of Cthrc1 characterizes differentiated smooth muscle. Arterioscler Thromb Vasc Biol 28: 1332-8 PubMed GONUTS page
  3. 3.0 3.1 3.2 Kimura H et al. (2008) Cthrc1 is a positive regulator of osteoblastic bone formation. PLoS One 3: e3174 PubMed GONUTS page
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