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MGI:Cth
Contents |
| Species (Taxon ID) | Mus musculus (house mouse) (taxon:10090) | |
| Gene Name(s) | Cth ( synonyms: CSE ) | |
| Protein Name(s) | cystathionase (cystathionine gamma-lyase), | |
| External Links | ||
| MGI | MGI:1339968 | |
Annotations
| Qualifier | GO ID | GO term name | Reference | Evidence Code | with/from | Aspect | Notes | Status |
|---|---|---|---|---|---|---|---|---|
| GO:0003824 |
catalytic activity |
MGI:MGI:2152098 |
IEA: Inferred from Electronic Annotation |
F |
From MGI |
|||
| GO:0004121 |
cystathionine beta-lyase activity |
MGI:MGI:4417868 |
ISO: Inferred from Sequence Orthology |
F |
From MGI |
|||
| GO:0004123 |
cystathionine gamma-lyase activity |
MGI:MGI:3046000 |
IDA: Inferred from Direct Assay |
F |
From MGI |
|||
| GO:0004123 |
cystathionine gamma-lyase activity |
MGI:MGI:4834177 |
ISO: Inferred from Sequence Orthology |
F |
From MGI |
|||
| GO:0005515 |
protein binding |
MGI:MGI:5304595 |
IPI: Inferred from Physical Interaction |
F |
From MGI |
|||
| GO:0005515 |
protein binding |
MGI:MGI:5315686 |
IPI: Inferred from Physical Interaction |
F |
From MGI |
|||
| GO:0005516 |
calmodulin binding |
MGI:MGI:1354194 |
IEA: Inferred from Electronic Annotation |
UniProtKB-KW:KW-0112 |
F |
From MGI |
||
| GO:0005634 |
nucleus |
MGI:MGI:4834177 |
ISO: Inferred from Sequence Orthology |
C |
From MGI |
|||
| GO:0005737 |
cytoplasm |
MGI:MGI:4834177 |
ISO: Inferred from Sequence Orthology |
C |
From MGI |
|||
| GO:0006520 |
cellular amino acid metabolic process |
MGI:MGI:2152098 |
IEA: Inferred from Electronic Annotation |
P |
From MGI |
|||
| GO:0006749 |
glutathione metabolic process |
MGI:MGI:4417868 |
ISO: Inferred from Sequence Orthology |
P |
From MGI |
|||
| GO:0006916 |
anti-apoptosis |
MGI:MGI:5304595 |
IMP: Inferred from Mutant Phenotype |
P |
From MGI |
|||
| GO:0008285 |
negative regulation of cell proliferation |
MGI:MGI:4417868 |
ISO: Inferred from Sequence Orthology |
P |
From MGI |
|||
| GO:0008652 |
cellular amino acid biosynthetic process |
MGI:MGI:1354194 |
IEA: Inferred from Electronic Annotation |
UniProtKB-KW:KW-0028 |
P |
From MGI |
||
| GO:0016829 |
lyase activity |
MGI:MGI:1354194 |
IEA: Inferred from Electronic Annotation |
UniProtKB-KW:KW-0456 |
F |
From MGI |
||
| GO:0018272 |
protein-pyridoxal-5-phosphate linkage via peptidyl-N6-pyridoxal phosphate-L-lysine |
MGI:MGI:4834177 |
ISO: Inferred from Sequence Orthology |
P |
From MGI |
|||
| GO:0019344 |
cysteine biosynthetic process |
MGI:MGI:4417868 |
ISO: Inferred from Sequence Orthology |
P |
From MGI |
|||
| GO:0019344 |
cysteine biosynthetic process |
MGI:MGI:4834177 |
ISO: Inferred from Sequence Orthology |
P |
From MGI |
|||
| GO:0030170 |
pyridoxal phosphate binding |
MGI:MGI:4834177 |
ISO: Inferred from Sequence Orthology |
F |
From MGI |
|||
| GO:0030308 |
negative regulation of cell growth |
MGI:MGI:4417868 |
ISO: Inferred from Sequence Orthology |
P |
From MGI |
|||
| GO:0043123 |
positive regulation of I-kappaB kinase/NF-kappaB cascade |
MGI:MGI:5304595 |
IMP: Inferred from Mutant Phenotype |
P |
From MGI |
|||
| GO:0044524 |
protein sulfhydration |
MGI:MGI:4834177 |
ISO: Inferred from Sequence Orthology |
P |
From MGI |
|||
| GO:0044524 |
protein sulfhydration |
MGI:MGI:5304595 |
IDA: Inferred from Direct Assay |
P |
From MGI |
|||
| GO:0044524 |
protein sulfhydration |
MGI:MGI:5315686 |
IMP: Inferred from Mutant Phenotype |
P |
From MGI |
|||
| GO:0044540 |
L-cystine L-cysteine-lyase (deaminating) |
MGI:MGI:4834177 |
ISO: Inferred from Sequence Orthology |
F |
From MGI |
|||
| GO:0044540 |
L-cystine L-cysteine-lyase (deaminating) |
MGI:MGI:5304595 |
IDA: Inferred from Direct Assay |
F |
From MGI |
|||
| GO:0044540 |
L-cystine L-cysteine-lyase (deaminating) |
MGI:MGI:5315686 |
IMP: Inferred from Mutant Phenotype |
F |
From MGI |
|||
| GO:0050667 |
homocysteine metabolic process |
MGI:MGI:4417868 |
ISO: Inferred from Sequence Orthology |
P |
From MGI |
|||
| GO:0051092 |
positive regulation of NF-kappaB transcription factor activity |
MGI:MGI:5304595 |
IMP: Inferred from Mutant Phenotype |
P |
From MGI |
|||
| GO:0051289 |
protein homotetramerization |
MGI:MGI:4834177 |
ISO: Inferred from Sequence Orthology |
P |
From MGI |
|||
| GO:0070814 |
hydrogen sulfide biosynthetic process |
MGI:MGI:4834177 |
ISO: Inferred from Sequence Orthology |
P |
From MGI |
|||
| GO:0080146 |
L-cysteine desulfhydrase activity |
MGI:MGI:2152096 |
IEA: Inferred from Electronic Annotation |
F |
From MGI |
| ||
| edit table |
Notes
References
See Help:References for how to manage references in GONUTS.
- ↑ Ishii I et al. (2004) Murine cystathionine gamma-lyase: complete cDNA and genomic sequences, promoter activity, tissue distribution and developmental expression. Biochem J 381: 113-23 PubMed GONUTS page
- ↑ 2.0 2.1 2.2 2.3 2.4 2.5 Sen N et al. (2012) Hydrogen sulfide-linked sulfhydration of NF-κB mediates its antiapoptotic actions. Mol Cell 45: 13-24 PubMed GONUTS page
- ↑ 3.0 3.1 3.2 Mustafa AK et al. (2009) H2S signals through protein S-sulfhydration. Sci Signal 2: ra72 PubMed GONUTS page
