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MGI:Ctbp2
Contents |
| Species (Taxon ID) | Mus musculus (house mouse) (taxon:10090) | |
| Gene Name(s) | Ctbp2 ( synonyms: D7Ertd45e, Gtrgeo6, Ribeye ) | |
| Protein Name(s) | C-terminal binding protein 2, | |
| External Links | ||
| MGI | MGI:1201686 | |
Annotations
| Qualifier | GO ID | GO term name | Reference | Evidence Code | with/from | Aspect | Notes | Status |
|---|---|---|---|---|---|---|---|---|
| GO:0000166 |
nucleotide binding |
MGI:MGI:2152098 |
IEA: Inferred from Electronic Annotation |
F |
From MGI |
|||
| GO:0003714 |
transcription corepressor activity |
MGI:MGI:1349212 |
IDA: Inferred from Direct Assay |
F |
From MGI |
|||
| GO:0003714 |
transcription corepressor activity |
MGI:MGI:2446766 |
IPI: Inferred from Physical Interaction |
F |
From MGI |
|||
| GO:0005515 |
protein binding |
MGI:MGI:1342875 |
IPI: Inferred from Physical Interaction |
F |
From MGI |
|||
| GO:0005515 |
protein binding |
MGI:MGI:2446766 |
IPI: Inferred from Physical Interaction |
F |
From MGI |
|||
| GO:0005515 |
protein binding |
MGI:MGI:3688378 |
IPI: Inferred from Physical Interaction |
F |
From MGI |
|||
| GO:0005515 |
protein binding |
MGI:MGI:3689671 |
IPI: Inferred from Physical Interaction |
F |
From MGI |
|||
| GO:0005515 |
protein binding |
MGI:MGI:4418632 |
IPI: Inferred from Physical Interaction |
F |
From MGI |
|||
| GO:0005515 |
protein binding |
MGI:MGI:4839443 |
IPI: Inferred from Physical Interaction |
F |
From MGI |
|||
| GO:0005515 |
protein binding |
MGI:MGI:5009348 |
IPI: Inferred from Physical Interaction |
F |
From MGI |
|||
| GO:0005515 |
protein binding |
MGI:MGI:5306305 |
IPI: Inferred from Physical Interaction |
F |
From MGI |
|||
| GO:0005634 |
nucleus |
MGI:MGI:4365360 |
IDA: Inferred from Direct Assay |
C |
From MGI |
|||
| GO:0006351 |
transcription, DNA-dependent |
MGI:MGI:1354194 |
IEA: Inferred from Electronic Annotation |
UniProtKB-KW:KW-0804 |
P |
From MGI |
||
| GO:0006355 |
regulation of transcription, DNA-dependent |
MGI:MGI:1354194 |
IEA: Inferred from Electronic Annotation |
UniProtKB-KW:KW-0805 |
P |
From MGI |
||
| GO:0008152 |
metabolic process |
MGI:MGI:2152098 |
IEA: Inferred from Electronic Annotation |
P |
From MGI |
|||
| GO:0016491 |
oxidoreductase activity |
MGI:MGI:1354194 |
IEA: Inferred from Electronic Annotation |
UniProtKB-KW:KW-0560 |
F |
From MGI |
||
| GO:0016616 |
oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor |
MGI:MGI:2152098 |
IEA: Inferred from Electronic Annotation |
F |
From MGI |
|||
| GO:0017053 |
transcriptional repressor complex |
MGI:MGI:4365360 |
IDA: Inferred from Direct Assay |
C |
From MGI |
|||
| GO:0030054 |
cell junction |
MGI:MGI:1354194 |
IEA: Inferred from Electronic Annotation |
UniProtKB-KW:KW-0965 |
C |
From MGI |
||
| GO:0030154 |
cell differentiation |
MGI:MGI:1354194 |
IEA: Inferred from Electronic Annotation |
UniProtKB-KW:KW-0221 |
P |
From MGI |
||
| GO:0045202 |
synapse |
MGI:MGI:4460838 |
IDA: Inferred from Direct Assay |
C |
From MGI |
|||
| GO:0045892 |
negative regulation of transcription, DNA-dependent |
MGI:MGI:2446766 |
IPI: Inferred from Physical Interaction |
P |
From MGI |
|||
| GO:0045892 |
negative regulation of transcription, DNA-dependent |
MGI:MGI:4365360 |
IDA: Inferred from Direct Assay |
P |
From MGI |
|||
| GO:0048037 |
cofactor binding |
MGI:MGI:2152098 |
IEA: Inferred from Electronic Annotation |
F |
From MGI |
|||
| GO:0050872 |
white fat cell differentiation |
MGI:MGI:4365360 |
IDA: Inferred from Direct Assay |
P |
From MGI |
|||
| GO:0051287 |
NAD binding |
MGI:MGI:2152098 |
IEA: Inferred from Electronic Annotation |
F |
From MGI |
|||
| GO:0055114 |
oxidation-reduction process |
MGI:MGI:1354194 |
IEA: Inferred from Electronic Annotation |
UniProtKB-KW:KW-0560 |
P |
From MGI |
||
| GO:0055114 |
oxidation-reduction process |
MGI:MGI:2152098 |
IEA: Inferred from Electronic Annotation |
P |
From MGI |
| ||
| edit table |
Notes
References
See Help:References for how to manage references in GONUTS.
- ↑ Furusawa T et al. (1999) Identification of CtBP1 and CtBP2 as corepressors of zinc finger-homeodomain factor deltaEF1. Mol Cell Biol 19: 8581-90 PubMed GONUTS page
- ↑ 2.0 2.1 2.2 Perdomo J & Crossley M (2002) The Ikaros family protein Eos associates with C-terminal-binding protein corepressors. Eur J Biochem 269: 5885-92 PubMed GONUTS page
- ↑ Holmes M et al. (1999) hFOG-2, a novel zinc finger protein, binds the co-repressor mCtBP2 and modulates GATA-mediated activation. J Biol Chem 274: 23491-8 PubMed GONUTS page
- ↑ Christian M et al. (2004) Characterization of four autonomous repression domains in the corepressor receptor interacting protein 140. J Biol Chem 279: 15645-51 PubMed GONUTS page
- ↑ Quinlan KG et al. (2006) Specific recognition of ZNF217 and other zinc finger proteins at a surface groove of C-terminal binding proteins. Mol Cell Biol 26: 8159-72 PubMed GONUTS page
- ↑ Palmer S et al. (2001) Evi-1 transforming and repressor activities are mediated by CtBP co-repressor proteins. J Biol Chem 276: 25834-40 PubMed GONUTS page
- ↑ McGilvray R et al. (2007) UXT interacts with the transcriptional repressor protein EVI1 and suppresses cell transformation. FEBS J 274: 3960-71 PubMed GONUTS page
- ↑ Jack BH & Crossley M (2010) GATA proteins work together with friend of GATA (FOG) and C-terminal binding protein (CTBP) co-regulators to control adipogenesis. J Biol Chem 285: 32405-14 PubMed GONUTS page
- ↑ Stankovic-Valentin N et al. (2006) A L225A substitution in the human tumour suppressor HIC1 abolishes its interaction with the corepressor CtBP. FEBS J 273: 2879-90 PubMed GONUTS page
- ↑ 10.0 10.1 10.2 10.3 Kajimura S et al. (2008) Regulation of the brown and white fat gene programs through a PRDM16/CtBP transcriptional complex. Genes Dev 22: 1397-409 PubMed GONUTS page
- ↑ Sedmak T & Wolfrum U (2010) Intraflagellar transport molecules in ciliary and nonciliary cells of the retina. J Cell Biol 189: 171-86 PubMed GONUTS page