Ambox notice.png

GONUTS is under stress! The website is currently experiencing long-wait times and frequent time-outs due to the record number of students, groups, and annotations related to CACAO this semester. We are currently working on increasing performance -- please accept our apologies for the technical difficulties.

You can help reduce stress on the server by:

  1. not reloading pages frequently - this just adds
  2. opening links in new windows (so you can read the old page)

MGI:Crx

From GONUTS
Jump to: navigation, search

Contents

Species (Taxon ID) Mus musculus (house mouse) (taxon:10090)
Gene Name(s) Crx ( synonyms: Crx1 )
Protein Name(s) cone-rod homeobox containing gene,
External Links
MGI MGI:1194883

Annotations

Qualifier GO ID GO term name Reference Evidence Code with/from Aspect Notes Status
GO:0003677

DNA binding

MGI:MGI:4417868

ISO: Inferred from Sequence Orthology

NCBI:NP_068627

F

From MGI

GO:0003682

chromatin binding

MGI:MGI:2684525
PMID:14613968[1]

IDA: Inferred from Direct Assay

F

From MGI

GO:0003700

sequence-specific DNA binding transcription factor activity

MGI:MGI:3574255
PMID:15689355[2]

IDA: Inferred from Direct Assay

F

From MGI

GO:0005515

protein binding

MGI:MGI:2684525
PMID:14613968[1]

IPI: Inferred from Physical Interaction

UniProtKB:Q8R4I1

F

From MGI

GO:0005515

protein binding

MGI:MGI:3574255
PMID:15689355[2]

IPI: Inferred from Physical Interaction

UniProtKB:Q9QXZ7

F

From MGI

GO:0005634

nucleus

MGI:MGI:3574255
PMID:15689355[2]

IDA: Inferred from Direct Assay

C

From MGI

GO:0005634

nucleus

MGI:MGI:4417868

ISO: Inferred from Sequence Orthology

NCBI:NP_068627

C

From MGI

GO:0005667

transcription factor complex

MGI:MGI:3574255
PMID:15689355[2]

IDA: Inferred from Direct Assay

C

From MGI

GO:0006351

transcription, DNA-dependent

MGI:MGI:1354194

IEA: Inferred from Electronic Annotation

UniProtKB-KW:KW-0804

P

From MGI

GO:0006355

regulation of transcription, DNA-dependent

MGI:MGI:1354194

IEA: Inferred from Electronic Annotation

UniProtKB-KW:KW-0805

P

From MGI

GO:0006355

regulation of transcription, DNA-dependent

MGI:MGI:2152098

IEA: Inferred from Electronic Annotation

InterPro:IPR017970
InterPro:IPR001356

P

From MGI

GO:0007275

multicellular organismal development

MGI:MGI:2152098

IEA: Inferred from Electronic Annotation

InterPro:IPR013851

P

From MGI

GO:0043522

leucine zipper domain binding

MGI:MGI:4834177

ISO: Inferred from Sequence Orthology

UniProtKB:O43186

F

From MGI

GO:0043565

sequence-specific DNA binding

MGI:MGI:2152098

IEA: Inferred from Electronic Annotation

InterPro:IPR017970
InterPro:IPR001356

F

From MGI

GO:0045944

positive regulation of transcription from RNA polymerase II promoter

MGI:MGI:2684525
PMID:14613968[1]

IDA: Inferred from Direct Assay

P

From MGI

GO:0045944

positive regulation of transcription from RNA polymerase II promoter

MGI:MGI:3574255
PMID:15689355[2]

IDA: Inferred from Direct Assay

P

From MGI

GO:0045944

positive regulation of transcription from RNA polymerase II promoter

MGI:MGI:3624051
PMID:12407160[3]

IDA: Inferred from Direct Assay

P

From MGI

GO:0045944

positive regulation of transcription from RNA polymerase II promoter

MGI:MGI:3624051
PMID:12407160[3]

IGI: Inferred from Genetic Interaction

MGI:MGI:98743

P

From MGI

GO:0045944

positive regulation of transcription from RNA polymerase II promoter

MGI:MGI:3628739
PMID:16539743[4]

IDA: Inferred from Direct Assay

P

From MGI

GO:0060041

retina development in camera-type eye

MGI:MGI:4849309
PMID:21052544[5]

IMP: Inferred from Mutant Phenotype

P

From MGI


Notes

References

See Help:References for how to manage references in GONUTS.
  1. 1.0 1.1 1.2 Chen S et al. (2004) Interference of Crx-dependent transcription by ataxin-7 involves interaction between the glutamine regions and requires the ataxin-7 carboxy-terminal region for nuclear localization. Hum Mol Genet 13: 53-67 PubMed GONUTS page
  2. 2.0 2.1 2.2 2.3 2.4 Peng GH et al. (2005) The photoreceptor-specific nuclear receptor Nr2e3 interacts with Crx and exerts opposing effects on the transcription of rod versus cone genes. Hum Mol Genet 14: 747-64 PubMed GONUTS page
  3. 3.0 3.1 Yanagi Y et al. (2002) Distinct functions of photoreceptor cell-specific nuclear receptor, thyroid hormone receptor beta2 and CRX in one photoreceptor development. Invest Ophthalmol Vis Sci 43: 3489-94 PubMed GONUTS page
  4. Inoue T et al. (2006) Cloning and characterization of mr-s, a novel SAM domain protein, predominantly expressed in retinal photoreceptor cells. BMC Dev Biol 6: 15 PubMed GONUTS page
  5. Won J et al. (2011) Mouse model resources for vision research. J Ophthalmol 2011: 391384 PubMed GONUTS page
Personal tools
Namespaces
Variants
Actions
Navigation
Cacao
Journal Clubs
page contributors
Toolbox