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MGI:Crh

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Contents

Species (Taxon ID) Mus musculus (house mouse) (taxon:10090)
Gene Name(s) Crh ( synonyms: corticotropin releasing factor, corticotropin-releasing factor, CRF, LOC383938 )
Protein Name(s) corticotropin releasing hormone,
External Links
MGI MGI:88496

Annotations

Qualifier GO ID GO term name Reference Evidence Code with/from Aspect Notes Status
GO:0001934

positive regulation of protein phosphorylation

MGI:MGI:4417868

ISO: Inferred from Sequence Orthology

UniProtKB:P01143

P

From MGI

GO:0001963

synaptic transmission, dopaminergic

MGI:MGI:4417868

ISO: Inferred from Sequence Orthology

UniProtKB:P01143

P

From MGI

GO:0001963

synaptic transmission, dopaminergic

MGI:MGI:4834177

ISO: Inferred from Sequence Orthology

UniProtKB:P06850

P

From MGI

GO:0005102

receptor binding

MGI:MGI:4417868

ISO: Inferred from Sequence Orthology

UniProtKB:P01143

F

From MGI

GO:0005179

hormone activity

MGI:MGI:1354194

IEA: Inferred from Electronic Annotation

UniProtKB-KW:KW-0372

F

From MGI

GO:0005179

hormone activity

MGI:MGI:2152098

IEA: Inferred from Electronic Annotation

InterPro:IPR000187
InterPro:IPR003620

F

From MGI

GO:0005576

extracellular region

MGI:MGI:1354194

IEA: Inferred from Electronic Annotation

UniProtKB-KW:KW-0964

C

From MGI

GO:0005576

extracellular region

MGI:MGI:2152098

IEA: Inferred from Electronic Annotation

InterPro:IPR000187
InterPro:IPR003620

C

From MGI

GO:0005615

extracellular space

MGI:MGI:4417868

ISO: Inferred from Sequence Orthology

UniProtKB:P01143

C

From MGI

GO:0005615

extracellular space

MGI:MGI:4834177

ISO: Inferred from Sequence Orthology

UniProtKB:P06850

C

From MGI

GO:0005737

cytoplasm

MGI:MGI:4417868

ISO: Inferred from Sequence Orthology

UniProtKB:P01143

C

From MGI

GO:0006704

glucocorticoid biosynthetic process

MGI:MGI:1860037
PMID:10861000[1]

IMP: Inferred from Mutant Phenotype

MGI:MGI:1857392

P

From MGI

GO:0006950

response to stress

MGI:MGI:4417868

ISO: Inferred from Sequence Orthology

UniProtKB:P01143

P

From MGI

GO:0006954

inflammatory response

MGI:MGI:3044469
PMID:15159534[2]

IMP: Inferred from Mutant Phenotype

MGI:MGI:1857392

P

From MGI

GO:0006954

inflammatory response

MGI:MGI:4834177

ISO: Inferred from Sequence Orthology

UniProtKB:P06850

P

From MGI

GO:0007565

female pregnancy

MGI:MGI:4834177

ISO: Inferred from Sequence Orthology

UniProtKB:P06850

P

From MGI

GO:0007611

learning or memory

MGI:MGI:4417868

ISO: Inferred from Sequence Orthology

UniProtKB:P01143

P

From MGI

GO:0007616

long-term memory

MGI:MGI:4417868

ISO: Inferred from Sequence Orthology

UniProtKB:P01143

P

From MGI

GO:0007631

feeding behavior

MGI:MGI:4417868

ISO: Inferred from Sequence Orthology

UniProtKB:P01143

P

From MGI

GO:0008284

positive regulation of cell proliferation

MGI:MGI:4417868

ISO: Inferred from Sequence Orthology

UniProtKB:P01143

P

From MGI

GO:0008306

associative learning

MGI:MGI:4417868

ISO: Inferred from Sequence Orthology

UniProtKB:P01143

P

From MGI

GO:0008628

induction of apoptosis by hormones

MGI:MGI:4417868

ISO: Inferred from Sequence Orthology

UniProtKB:P01143

P

From MGI

GO:0010628

positive regulation of gene expression

MGI:MGI:4417868

ISO: Inferred from Sequence Orthology

UniProtKB:P01143

P

From MGI

GO:0010629

negative regulation of gene expression

MGI:MGI:4417868

ISO: Inferred from Sequence Orthology

UniProtKB:P01143

P

From MGI

GO:0010700

negative regulation of norepinephrine secretion

MGI:MGI:4417868

ISO: Inferred from Sequence Orthology

UniProtKB:P01143

P

From MGI

GO:0010942

positive regulation of cell death

MGI:MGI:4417868

ISO: Inferred from Sequence Orthology

UniProtKB:P01143

P

From MGI

GO:0014062

regulation of serotonin secretion

MGI:MGI:4417868

ISO: Inferred from Sequence Orthology

UniProtKB:P01143

P

From MGI

GO:0017045

corticotropin-releasing hormone activity

MGI:MGI:4417868

ISO: Inferred from Sequence Orthology

UniProtKB:P01143

F

From MGI

GO:0030324

lung development

MGI:MGI:1860037
PMID:10861000[1]

IMP: Inferred from Mutant Phenotype

MGI:MGI:1857392

P

From MGI

GO:0030325

adrenal gland development

MGI:MGI:1860037
PMID:10861000[1]

IMP: Inferred from Mutant Phenotype

MGI:MGI:1857392

P

From MGI

GO:0030819

positive regulation of cAMP biosynthetic process

MGI:MGI:4417868

ISO: Inferred from Sequence Orthology

UniProtKB:P01143

P

From MGI

GO:0032811

negative regulation of epinephrine secretion

MGI:MGI:4417868

ISO: Inferred from Sequence Orthology

UniProtKB:P01143

P

From MGI

GO:0033685

negative regulation of luteinizing hormone secretion

MGI:MGI:4417868

ISO: Inferred from Sequence Orthology

UniProtKB:P01143

P

From MGI

GO:0035641

locomotory exploration behavior

MGI:MGI:3840767
PMID:17908177[3]

IGI: Inferred from Genetic Interaction

MGI:MGI:97599

P

From MGI

GO:0035774

positive regulation of insulin secretion involved in cellular response to glucose stimulus

MGI:MGI:4417868

ISO: Inferred from Sequence Orthology

UniProtKB:P01143

P

From MGI

GO:0043025

neuronal cell body

MGI:MGI:4417868

ISO: Inferred from Sequence Orthology

UniProtKB:P01143

C

From MGI

GO:0043196

varicosity

MGI:MGI:4417868

ISO: Inferred from Sequence Orthology

UniProtKB:P01143

C

From MGI

GO:0043204

perikaryon

MGI:MGI:4417868

ISO: Inferred from Sequence Orthology

UniProtKB:P01143

C

From MGI

GO:0043526

neuroprotection

MGI:MGI:4417868

ISO: Inferred from Sequence Orthology

UniProtKB:P01143

P

From MGI

GO:0045776

negative regulation of blood pressure

MGI:MGI:4417868

ISO: Inferred from Sequence Orthology

UniProtKB:P01143

P

From MGI

GO:0051430

corticotropin-releasing hormone receptor 1 binding

MGI:MGI:4417868

ISO: Inferred from Sequence Orthology

UniProtKB:P01143

F

From MGI

GO:0051431

corticotropin-releasing hormone receptor 2 binding

MGI:MGI:4417868

ISO: Inferred from Sequence Orthology

UniProtKB:P01143

F

From MGI

GO:0051461

positive regulation of corticotropin secretion

MGI:MGI:4417868

ISO: Inferred from Sequence Orthology

UniProtKB:P01143

P

From MGI

GO:0051464

positive regulation of cortisol secretion

MGI:MGI:4834177

ISO: Inferred from Sequence Orthology

UniProtKB:P06850

P

From MGI

GO:0060456

positive regulation of digestive system process

MGI:MGI:4417868

ISO: Inferred from Sequence Orthology

UniProtKB:P01143

P

From MGI

GO:0060548

negative regulation of cell death

MGI:MGI:4417868

ISO: Inferred from Sequence Orthology

UniProtKB:P01143

P

From MGI

GO:0070093

negative regulation of glucagon secretion

MGI:MGI:4417868

ISO: Inferred from Sequence Orthology

UniProtKB:P01143

P

From MGI

GO:0071314

cellular response to cocaine

MGI:MGI:4417868

ISO: Inferred from Sequence Orthology

UniProtKB:P01143

P

From MGI

GO:0090280

positive regulation of calcium ion import

MGI:MGI:4417868

ISO: Inferred from Sequence Orthology

UniProtKB:P01143

P

From MGI

GO:2000310

regulation of N-methyl-D-aspartate selective glutamate receptor activity

MGI:MGI:4417868

ISO: Inferred from Sequence Orthology

UniProtKB:P01143

P

From MGI

GO:2000310

regulation of N-methyl-D-aspartate selective glutamate receptor activity

MGI:MGI:4834177

ISO: Inferred from Sequence Orthology

UniProtKB:P06850

P

From MGI

GO:2000854

positive regulation of corticosterone secretion

MGI:MGI:4417868

ISO: Inferred from Sequence Orthology

UniProtKB:P01143

P

From MGI

GO:2000987

positive regulation of behavioral fear response

MGI:MGI:4417868

ISO: Inferred from Sequence Orthology

UniProtKB:P01143

P

From MGI


Notes

References

See Help:References for how to manage references in GONUTS.
  1. 1.0 1.1 1.2 Venihaki M et al. (2000) Circadian rise in maternal glucocorticoid prevents pulmonary dysplasia in fetal mice with adrenal insufficiency. Proc Natl Acad Sci U S A 97: 7336-41 PubMed GONUTS page
  2. Anton PM et al. (2004) Corticotropin-releasing hormone (CRH) requirement in Clostridium difficile toxin A-mediated intestinal inflammation. Proc Natl Acad Sci U S A 101: 8503-8 PubMed GONUTS page
  3. Lesscher HM et al. (2008) Amygdala protein kinase C epsilon regulates corticotropin-releasing factor and anxiety-like behavior. Genes Brain Behav 7: 323-33 PubMed GONUTS page
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