Ambox notice.png

GONUTS is under stress! The website is currently experiencing long-wait times and frequent time-outs due to the record number of students, groups, and annotations related to CACAO this semester. We are currently working on increasing performance -- please accept our apologies for the technical difficulties.

You can help reduce stress on the server by:

  1. not reloading pages frequently - this just adds
  2. opening links in new windows (so you can read the old page)

MGI:Cr2

From GONUTS
Jump to: navigation, search

Contents

Species (Taxon ID) Mus musculus (house mouse) (taxon:10090)
Gene Name(s) Cr2 ( synonyms: C3DR, CD21, CD35, Cr-1, Cr-2, Cr1 )
Protein Name(s) complement receptor 2,
External Links
MGI MGI:88489

Annotations

Qualifier GO ID GO term name Reference Evidence Code with/from Aspect Notes Status
GO:0004872

receptor activity

MGI:MGI:2154602
PMID:11728339[1]

IDA: Inferred from Direct Assay

F

From MGI

GO:0004875

complement receptor activity

MGI:MGI:2154602
PMID:11728339[1]

IMP: Inferred from Mutant Phenotype

MGI:MGI:2154453

F

From MGI

GO:0005515

protein binding

MGI:MGI:2154602
PMID:11728339[1]

IPI: Inferred from Physical Interaction

UniProtKB:P01027

F

From MGI

GO:0009897

external side of plasma membrane

MGI:MGI:3028699
PMID:14662849[2]

IDA: Inferred from Direct Assay

C

From MGI

GO:0009897

external side of plasma membrane

MGI:MGI:3581459
PMID:15909309[3]

IDA: Inferred from Direct Assay

C

From MGI

GO:0009897

external side of plasma membrane

MGI:MGI:3640996
PMID:11435465[4]

IDA: Inferred from Direct Assay

C

From MGI

GO:0009897

external side of plasma membrane

MGI:MGI:67606
PMID:8041705[5]

IDA: Inferred from Direct Assay

C

From MGI

GO:0042113

B cell activation

MGI:MGI:55783
PMID:6363792[6]

IMP: Inferred from Mutant Phenotype

MGI:MGI:2154453

P

From MGI

GO:0042803

protein homodimerization activity

MGI:MGI:2154602
PMID:11728339[1]

ISO: Inferred from Sequence Orthology

UniProtKB:P20023

F

From MGI


Notes

References

See Help:References for how to manage references in GONUTS.
  1. 1.0 1.1 1.2 1.3 Boackle SA et al. (2001) Cr2, a candidate gene in the murine Sle1c lupus susceptibility locus, encodes a dysfunctional protein. Immunity 15: 775-85 PubMed GONUTS page
  2. Kretschmer K et al. (2003) The selection of marginal zone B cells differs from that of B-1a cells. J Immunol 171: 6495-501 PubMed GONUTS page
  3. Erlandsson L et al. (2005) Both the pre-BCR and the IL-7Ralpha are essential for expansion at the pre-BII cell stage in vivo. Eur J Immunol 35: 1969-76 PubMed GONUTS page
  4. Apasov SG et al. (2001) Adenosine deaminase deficiency increases thymic apoptosis and causes defective T cell receptor signaling. J Clin Invest 108: 131-41 PubMed GONUTS page
  5. Fujiwara H et al. (1994) The absence of IgE antibody-mediated augmentation of immune responses in CD23-deficient mice. Proc Natl Acad Sci U S A 91: 6835-9 PubMed GONUTS page
  6. Bubbers JE (1984) Identification and linkage analyses of a gene, Rcs-1, suppressing spontaneous SJL/J lymphoma expression. J Natl Cancer Inst 72: 441-6 PubMed GONUTS page
Personal tools
Namespaces
Variants
Actions
Navigation
Cacao
Journal Clubs
page contributors
Toolbox