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MGI:Cps1

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Contents

Species (Taxon ID) Mus musculus (house mouse) (taxon:10090)
Gene Name(s) Cps1 ( synonyms: CPS, CPSase I, D1Ucla3 )
Protein Name(s) carbamoyl-phosphate synthetase 1,
External Links
MGI MGI:891996

Annotations

Qualifier GO ID GO term name Reference Evidence Code with/from Aspect Notes Status
GO:0000050

urea cycle

MGI:MGI:1328875
PMID:9862865[1]

IC: Inferred by Curator

GO:0004087

P

From MGI

GO:0000050

urea cycle

MGI:MGI:4417868

ISO: Inferred from Sequence Orthology

UniProtKB:P07756

P

From MGI

GO:0000166

nucleotide binding

MGI:MGI:1354194

IEA: Inferred from Electronic Annotation

UniProtKB-KW:KW-0547

F

From MGI

GO:0003824

catalytic activity

MGI:MGI:1354194

IEA: Inferred from Electronic Annotation

UniProtKB-KW:KW-0021

F

From MGI

GO:0003824

catalytic activity

MGI:MGI:2152098

IEA: Inferred from Electronic Annotation

InterPro:IPR013815
InterPro:IPR005479
InterPro:IPR005481

F

From MGI

GO:0004087

carbamoyl-phosphate synthase (ammonia) activity

MGI:MGI:1328875
PMID:9862865[1]

IMP: Inferred from Mutant Phenotype

MGI:MGI:2386969

F

From MGI

GO:0004087

carbamoyl-phosphate synthase (ammonia) activity

MGI:MGI:4417868

ISO: Inferred from Sequence Orthology

UniProtKB:P07756

F

From MGI

GO:0004087

carbamoyl-phosphate synthase (ammonia) activity

MGI:MGI:4834177

ISO: Inferred from Sequence Orthology

UniProtKB:P31327

F

From MGI

GO:0004175

endopeptidase activity

MGI:MGI:4417868

ISO: Inferred from Sequence Orthology

UniProtKB:P07756

F

From MGI

GO:0005509

calcium ion binding

MGI:MGI:4417868

ISO: Inferred from Sequence Orthology

UniProtKB:P07756

F

From MGI

GO:0005515

protein binding

MGI:MGI:3846470
PMID:19410549[2]

IPI: Inferred from Physical Interaction

UniProtKB:Q8K2C6

F

From MGI

GO:0005524

ATP binding

MGI:MGI:4417868

ISO: Inferred from Sequence Orthology

UniProtKB:P07756

F

From MGI

GO:0005543

phospholipid binding

MGI:MGI:4417868

ISO: Inferred from Sequence Orthology

UniProtKB:P07756

F

From MGI

GO:0005737

cytoplasm

MGI:MGI:4417868

ISO: Inferred from Sequence Orthology

UniProtKB:P07756

C

From MGI

GO:0005739

mitochondrion

MGI:MGI:3831659
PMID:6200105[3]

IDA: Inferred from Direct Assay

C

From MGI

GO:0005739

mitochondrion

MGI:MGI:4417868

ISO: Inferred from Sequence Orthology

UniProtKB:P07756

C

From MGI

GO:0005743

mitochondrial inner membrane

MGI:MGI:4417868

ISO: Inferred from Sequence Orthology

UniProtKB:P07756

C

From MGI

GO:0005980

glycogen catabolic process

MGI:MGI:4834177

ISO: Inferred from Sequence Orthology

UniProtKB:P31327

P

From MGI

GO:0006543

glutamine catabolic process

MGI:MGI:2152098

IEA: Inferred from Electronic Annotation

InterPro:IPR006274

P

From MGI

GO:0006807

nitrogen compound metabolic process

MGI:MGI:2152098

IEA: Inferred from Electronic Annotation

InterPro:IPR006275
InterPro:IPR005483

P

From MGI

GO:0016595

glutamate binding

MGI:MGI:4417868

ISO: Inferred from Sequence Orthology

UniProtKB:P07756

F

From MGI

GO:0016874

ligase activity

MGI:MGI:1354194

IEA: Inferred from Electronic Annotation

UniProtKB-KW:KW-0436

F

From MGI

GO:0019433

triglyceride catabolic process

MGI:MGI:4834177

ISO: Inferred from Sequence Orthology

UniProtKB:P31327

P

From MGI

GO:0032403

protein complex binding

MGI:MGI:4417868

ISO: Inferred from Sequence Orthology

UniProtKB:P07756

F

From MGI

GO:0032496

response to lipopolysaccharide

MGI:MGI:4834177

ISO: Inferred from Sequence Orthology

UniProtKB:P31327

P

From MGI

GO:0042645

mitochondrial nucleoid

MGI:MGI:4834177

ISO: Inferred from Sequence Orthology

UniProtKB:P31327

C

From MGI

GO:0043234

protein complex

MGI:MGI:4417868

ISO: Inferred from Sequence Orthology

UniProtKB:P07756

C

From MGI

GO:0045909

positive regulation of vasodilation

MGI:MGI:4834177

ISO: Inferred from Sequence Orthology

UniProtKB:P31327

P

From MGI

GO:0046209

nitric oxide metabolic process

MGI:MGI:4834177

ISO: Inferred from Sequence Orthology

UniProtKB:P31327

P

From MGI

GO:0046872

metal ion binding

MGI:MGI:2152098

IEA: Inferred from Electronic Annotation

InterPro:IPR011761

F

From MGI

GO:0050667

homocysteine metabolic process

MGI:MGI:4834177

ISO: Inferred from Sequence Orthology

UniProtKB:P31327

P

From MGI

GO:0055081

anion homeostasis

MGI:MGI:4417868

ISO: Inferred from Sequence Orthology

UniProtKB:P07756

P

From MGI

GO:0070409

carbamoyl phosphate biosynthetic process

MGI:MGI:4834177

ISO: Inferred from Sequence Orthology

UniProtKB:P31327

P

From MGI

GO:0072341

modified amino acid binding

MGI:MGI:4834177

ISO: Inferred from Sequence Orthology

UniProtKB:P31327

F

From MGI


Notes

References

See Help:References for how to manage references in GONUTS.
  1. 1.0 1.1 Schofield JP et al. (1999) Mice deficient in the urea-cycle enzyme, carbamoyl phosphate synthetase I, die during the early neonatal period from hyperammonemia. Hepatology 29: 181-5 PubMed GONUTS page
  2. Nakagawa T et al. (2009) SIRT5 Deacetylates carbamoyl phosphate synthetase 1 and regulates the urea cycle. Cell 137: 560-70 PubMed GONUTS page
  3. Bhat NK & Avadhani NG (1984) The transport and processing of carbamyl phosphate synthetase-I in mouse hepatic mitochondria. Biochem Biophys Res Commun 118: 514-22 PubMed GONUTS page
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