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MGI:Col1a2
Contents |
| Species (Taxon ID) | Mus musculus (house mouse) (taxon:10090) | |
| Gene Name(s) | Col1a2 ( synonyms: Col1a-2, Cola-2, Cola2 ) | |
| Protein Name(s) | collagen, type I, alpha 2, | |
| External Links | ||
| MGI | MGI:88468 | |
Annotations
| Qualifier | GO ID | GO term name | Reference | Evidence Code | with/from | Aspect | Notes | Status |
|---|---|---|---|---|---|---|---|---|
| GO:0001501 |
skeletal system development |
MGI:MGI:4834177 |
ISO: Inferred from Sequence Orthology |
P |
From MGI |
|||
| GO:0001568 |
blood vessel development |
MGI:MGI:4834177 |
ISO: Inferred from Sequence Orthology |
P |
From MGI |
|||
| GO:0005201 |
extracellular matrix structural constituent |
MGI:MGI:2152098 |
IEA: Inferred from Electronic Annotation |
F |
From MGI |
|||
| GO:0005515 |
protein binding |
MGI:MGI:74938 |
IPI: Inferred from Physical Interaction |
UniPRotKB:P11087 |
F |
From MGI |
||
| GO:0005515 |
protein binding |
MGI:MGI:894584 |
IPI: Inferred from Physical Interaction |
F |
From MGI |
|||
| GO:0005576 |
extracellular region |
MGI:MGI:1354194 |
IEA: Inferred from Electronic Annotation |
UniProtKB-KW:KW-0964 |
C |
From MGI |
||
| GO:0005578 |
proteinaceous extracellular matrix |
MGI:MGI:1354194 |
IEA: Inferred from Electronic Annotation |
UniProtKB-KW:KW-0272 |
C |
From MGI |
||
| GO:0005581 |
collagen |
MGI:MGI:1351110 |
IDA: Inferred from Direct Assay |
C |
From MGI |
|||
| GO:0005581 |
collagen |
MGI:MGI:3766665 |
IDA: Inferred from Direct Assay |
C |
From MGI |
|||
| GO:0005581 |
collagen |
MGI:MGI:81870 |
IDA: Inferred from Direct Assay |
C |
From MGI |
|||
| GO:0005584 |
collagen type I |
MGI:MGI:4834177 |
ISO: Inferred from Sequence Orthology |
C |
From MGI |
|||
| GO:0005584 |
collagen type I |
MGI:MGI:68743 |
IDA: Inferred from Direct Assay |
C |
From MGI |
|||
| GO:0005615 |
extracellular space |
MGI:MGI:4834177 |
ISO: Inferred from Sequence Orthology |
C |
From MGI |
|||
| GO:0005622 |
intracellular |
MGI:MGI:4834177 |
ISO: Inferred from Sequence Orthology |
C |
From MGI |
|||
| GO:0007179 |
transforming growth factor beta receptor signaling pathway |
MGI:MGI:4834177 |
ISO: Inferred from Sequence Orthology |
P |
From MGI |
|||
| GO:0007266 |
Rho protein signal transduction |
MGI:MGI:4834177 |
ISO: Inferred from Sequence Orthology |
P |
From MGI |
|||
| GO:0008217 |
regulation of blood pressure |
MGI:MGI:4834177 |
ISO: Inferred from Sequence Orthology |
P |
From MGI |
|||
| GO:0030199 |
collagen fibril organization |
MGI:MGI:4834177 |
ISO: Inferred from Sequence Orthology |
P |
From MGI |
|||
| GO:0030674 |
protein binding, bridging |
MGI:MGI:4834177 |
ISO: Inferred from Sequence Orthology |
F |
From MGI |
|||
| GO:0042802 |
identical protein binding |
MGI:MGI:4834177 |
ISO: Inferred from Sequence Orthology |
F |
From MGI |
|||
| GO:0043589 |
skin morphogenesis |
MGI:MGI:4834177 |
ISO: Inferred from Sequence Orthology |
P |
From MGI |
|||
| GO:0046332 |
SMAD binding |
MGI:MGI:2679769 |
IPI: Inferred from Physical Interaction |
F |
From MGI |
|||
| GO:0048407 |
platelet-derived growth factor binding |
MGI:MGI:2154458 |
ISO: Inferred from Sequence Orthology |
F |
From MGI |
|||
| GO:0070208 |
protein heterotrimerization |
MGI:MGI:894584 |
IDA: Inferred from Direct Assay |
P |
From MGI |
|||
| GO:0071230 |
cellular response to amino acid stimulus |
MGI:MGI:4833768 |
IDA: Inferred from Direct Assay |
P |
From MGI |
| ||
| edit table |
Notes
References
See Help:References for how to manage references in GONUTS.
- ↑ Lamandé SR & Bateman JF (1995) The type I collagen pro alpha 1(I) COOH-terminal propeptide N-linked oligosaccharide. Functional analysis by site-directed mutagenesis. J Biol Chem 270: 17858-65 PubMed GONUTS page
- ↑ 2.0 2.1 Balk ML et al. (1997) Effect of rhBMP-2 on the osteogenic potential of bone marrow stromal cells from an osteogenesis imperfecta mouse (oim). Bone 21: 7-15 PubMed GONUTS page
- ↑ Forlino A et al. (1999) Use of the Cre/lox recombination system to develop a non-lethal knock-in murine model for osteogenesis imperfecta with an alpha1(I) G349C substitution. Variability in phenotype in BrtlIV mice. J Biol Chem 274: 37923-31 PubMed GONUTS page
- ↑ Forlino A et al. (2007) Selective retention and degradation of molecules with a single mutant alpha1(I) chain in the Brtl IV mouse model of OI. Matrix Biol 26: 604-14 PubMed GONUTS page
- ↑ Buck M et al. (1996) Tumor necrosis factor-alpha inhibits collagen alpha1(I) gene expression and wound healing in a murine model of cachexia. Am J Pathol 149: 195-204 PubMed GONUTS page
- ↑ Ohsaki Y & Nagata K (1994) Type III collagen is a major component of interodontoblastic fibers of the developing mouse molar root. Anat Rec 240: 308-13 PubMed GONUTS page
- ↑ Ellis LR et al. (2003) Interaction of Smads with collagen types I, III, and V. Biochem Biophys Res Commun 310: 1117-23 PubMed GONUTS page
- ↑ Pogribny IP et al. (2010) Difference in expression of hepatic microRNAs miR-29c, miR-34a, miR-155, and miR-200b is associated with strain-specific susceptibility to dietary nonalcoholic steatohepatitis in mice. Lab Invest 90: 1437-46 PubMed GONUTS page
