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MGI:Cnot6l

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Contents

Species (Taxon ID) Mus musculus (house mouse) (taxon:10090)
Gene Name(s) Cnot6l
Protein Name(s) CCR4-NOT transcription complex, subunit 6-like,
External Links
MGI MGI:2443154

Annotations

Qualifier GO ID GO term name Reference Evidence Code with/from Aspect Notes Status
GO:0000288

nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay

MGI:MGI:3828348
PMID:17452450[1]

IMP: Inferred from Mutant Phenotype

P

From MGI

GO:0004518

nuclease activity

MGI:MGI:1354194

IEA: Inferred from Electronic Annotation

UniProtKB-KW:KW-0540

F

From MGI

GO:0004527

exonuclease activity

MGI:MGI:1354194

IEA: Inferred from Electronic Annotation

UniProtKB-KW:KW-0269

F

From MGI

GO:0004535

poly(A)-specific ribonuclease activity

MGI:MGI:3828348
PMID:17452450[1]

IMP: Inferred from Mutant Phenotype

F

From MGI

GO:0005515

protein binding

MGI:MGI:3828348
PMID:17452450[1]

IPI: Inferred from Physical Interaction

UniProtKB:Q6ZQ08
UniProtKB:Q8K0V4
UniProtKB:Q9D0N7
UniProtKB:Q9JKY0

F

From MGI

GO:0005515

protein binding

MGI:MGI:4431145
PMID:20133598[2]

IPI: Inferred from Physical Interaction

UniProtKB:P60322

F

From MGI

GO:0005737

cytoplasm

MGI:MGI:3828348
PMID:17452450[1]

IDA: Inferred from Direct Assay

C

From MGI

GO:0006397

mRNA processing

MGI:MGI:1354194

IEA: Inferred from Electronic Annotation

UniProtKB-KW:KW-0507

P

From MGI

GO:0008284

positive regulation of cell proliferation

MGI:MGI:3828348
PMID:17452450[1]

IMP: Inferred from Mutant Phenotype

P

From MGI

GO:0016787

hydrolase activity

MGI:MGI:1354194

IEA: Inferred from Electronic Annotation

UniProtKB-KW:KW-0378

F

From MGI

GO:0046872

metal ion binding

MGI:MGI:1354194

IEA: Inferred from Electronic Annotation

UniProtKB-KW:KW-0479

F

From MGI

GO:0061157

mRNA destabilization

MGI:MGI:3828348
PMID:17452450[1]

IMP: Inferred from Mutant Phenotype

P

From MGI

GO:0090305

nucleic acid phosphodiester bond hydrolysis

MGI:MGI:1354194

IEA: Inferred from Electronic Annotation

UniProtKB-KW:KW-0269

P

From MGI

GO:0090305

nucleic acid phosphodiester bond hydrolysis

MGI:MGI:3828348
PMID:17452450[1]

IMP: Inferred from Mutant Phenotype

P

From MGI


Notes

References

See Help:References for how to manage references in GONUTS.
  1. 1.0 1.1 1.2 1.3 1.4 1.5 1.6 Morita M et al. (2007) Depletion of mammalian CCR4b deadenylase triggers elevation of the p27Kip1 mRNA level and impairs cell growth. Mol Cell Biol 27: 4980-90 PubMed GONUTS page
  2. Suzuki A et al. (2010) NANOS2 interacts with the CCR4-NOT deadenylation complex and leads to suppression of specific RNAs. Proc Natl Acad Sci U S A 107: 3594-9 PubMed GONUTS page
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