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MGI:Clgn

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Contents

Species (Taxon ID) Mus musculus (house mouse) (taxon:10090)
Gene Name(s) Clgn ( synonyms: A2/6, calnexin-t, Cln )
Protein Name(s) calmegin,
External Links
MGI MGI:107472

Annotations

Qualifier GO ID GO term name Reference Evidence Code with/from Aspect Notes Status
GO:0005509

calcium ion binding

MGI:MGI:1307001
PMID:9780330[1]

IDA: Inferred from Direct Assay

F

From MGI

GO:0005509

calcium ion binding

MGI:MGI:65304
PMID:8126001[2]

IDA: Inferred from Direct Assay

F

From MGI

GO:0005509

calcium ion binding

MGI:MGI:66204
PMID:8188695[3]

IDA: Inferred from Direct Assay

F

From MGI

GO:0005635

nuclear envelope

MGI:MGI:1351710
PMID:10495883[4]

IDA: Inferred from Direct Assay

C

From MGI

GO:0005783

endoplasmic reticulum

MGI:MGI:1351710
PMID:10495883[4]

IDA: Inferred from Direct Assay

C

From MGI

GO:0006457

protein folding

MGI:MGI:2152098

IEA: Inferred from Electronic Annotation

InterPro:IPR009033

P

From MGI

GO:0006461

protein complex assembly

MGI:MGI:2154902
PMID:11784061[5]

IMP: Inferred from Mutant Phenotype

MGI:MGI:2156041

P

From MGI

GO:0007126

meiosis

MGI:MGI:1354194

IEA: Inferred from Electronic Annotation

UniProtKB-KW:KW-0469

P

From MGI

GO:0007275

multicellular organismal development

MGI:MGI:1354194

IEA: Inferred from Electronic Annotation

UniProtKB-KW:KW-0217

P

From MGI

GO:0007283

spermatogenesis

MGI:MGI:1354194

IEA: Inferred from Electronic Annotation

UniProtKB-KW:KW-0744

P

From MGI

GO:0007339

binding of sperm to zona pellucida

MGI:MGI:2154902
PMID:11784061[5]

IMP: Inferred from Mutant Phenotype

MGI:MGI:2156041

P

From MGI

GO:0007339

binding of sperm to zona pellucida

MGI:MGI:892217
PMID:9177349[6]

IMP: Inferred from Mutant Phenotype

MGI:MGI:2156041

P

From MGI

GO:0016020

membrane

MGI:MGI:1354194

IEA: Inferred from Electronic Annotation

UniProtKB-KW:KW-0472

C

From MGI

GO:0016021

integral to membrane

MGI:MGI:1354194

IEA: Inferred from Electronic Annotation

UniProtKB-KW:KW-0812

C

From MGI

GO:0030154

cell differentiation

MGI:MGI:1354194

IEA: Inferred from Electronic Annotation

UniProtKB-KW:KW-0221

P

From MGI

GO:0051082

unfolded protein binding

MGI:MGI:2152098

IEA: Inferred from Electronic Annotation

InterPro:IPR009033

F

From MGI


Notes

References

See Help:References for how to manage references in GONUTS.
  1. Ohsako S et al. (1998) Characterization of domains in mice of calnexin-t, a putative molecular chaperone required in sperm fertility, with use of glutathione S-transferase-fusion proteins. Biol Reprod 59: 1214-23 PubMed GONUTS page
  2. Watanabe D et al. (1994) Molecular cloning of a novel Ca(2+)-binding protein (calmegin) specifically expressed during male meiotic germ cell development. J Biol Chem 269: 7744-9 PubMed GONUTS page
  3. Ohsako S et al. (1994) Molecular cloning and sequencing of calnexin-t. An abundant male germ cell-specific calcium-binding protein of the endoplasmic reticulum. J Biol Chem 269: 14140-8 PubMed GONUTS page
  4. 4.0 4.1 Yoshinaga K et al. (1999) Molecular chaperone calmegin localization to the endoplasmic reticulum of meiotic and post-meiotic germ cells in the mouse testis. Arch Histol Cytol 62: 283-93 PubMed GONUTS page
  5. 5.0 5.1 Ikawa M et al. (2001) Calmegin is required for fertilin alpha/beta heterodimerization and sperm fertility. Dev Biol 240: 254-61 PubMed GONUTS page
  6. Ikawa M et al. (1997) The putative chaperone calmegin is required for sperm fertility. Nature 387: 607-11 PubMed GONUTS page
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