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MGI:Cit
Contents |
| Species (Taxon ID) | Mus musculus (house mouse) (taxon:10090) | |
| Gene Name(s) | Cit ( synonyms: Cit-k, citron kinase, citron-N, CRIK-SK ) | |
| Protein Name(s) | citron, | |
| External Links | ||
| MGI | MGI:105313 | |
Annotations
| Qualifier | GO ID | GO term name | Reference | Evidence Code | with/from | Aspect | Notes | Status |
|---|---|---|---|---|---|---|---|---|
| GO:0000070 |
mitotic sister chromatid segregation |
MGI:MGI:3606716 |
IMP: Inferred from Mutant Phenotype |
MGI:MGI:2447844 |
P |
From MGI |
||
| GO:0000086 |
G2/M transition of mitotic cell cycle |
MGI:MGI:4417868 |
ISO: Inferred from Sequence Orthology |
P |
From MGI |
|||
| GO:0000166 |
nucleotide binding |
MGI:MGI:1354194 |
IEA: Inferred from Electronic Annotation |
UniProtKB-KW:KW-0547 |
F |
From MGI |
||
| GO:0000910 |
cytokinesis |
MGI:MGI:2181325 |
IMP: Inferred from Mutant Phenotype |
MGI:MGI:2447844 |
P |
From MGI |
||
| GO:0000910 |
cytokinesis |
MGI:MGI:2447488 |
IMP: Inferred from Mutant Phenotype |
MGI:MGI:2447844 |
P |
From MGI |
||
| GO:0001726 |
ruffle |
MGI:MGI:3608100 |
IDA: Inferred from Direct Assay |
C |
From MGI |
|||
| GO:0004672 |
protein kinase activity |
MGI:MGI:2152098 |
IEA: Inferred from Electronic Annotation |
F |
From MGI |
|||
| GO:0004674 |
protein serine/threonine kinase activity |
MGI:MGI:1312975 |
IDA: Inferred from Direct Assay |
F |
From MGI |
|||
| GO:0005083 |
small GTPase regulator activity |
MGI:MGI:2152098 |
IEA: Inferred from Electronic Annotation |
F |
From MGI |
|||
| GO:0005515 |
protein binding |
MGI:MGI:3696608 |
IPI: Inferred from Physical Interaction |
UniProtKB:P53804 |
F |
From MGI |
||
| GO:0005515 |
protein binding |
MGI:MGI:77862 |
IPI: Inferred from Physical Interaction |
UniProtKB:Q9QUI0 |
F |
From MGI |
||
| GO:0005524 |
ATP binding |
MGI:MGI:1354194 |
IEA: Inferred from Electronic Annotation |
UniProtKB-KW:KW-0067 |
F |
From MGI |
||
| GO:0005524 |
ATP binding |
MGI:MGI:2152098 |
IEA: Inferred from Electronic Annotation |
InterPro:IPR000961 |
F |
From MGI |
||
| GO:0005543 |
phospholipid binding |
MGI:MGI:2152098 |
IEA: Inferred from Electronic Annotation |
F |
From MGI |
|||
| GO:0005622 |
intracellular |
MGI:MGI:2152098 |
IEA: Inferred from Electronic Annotation |
C |
From MGI |
|||
| GO:0005624 |
membrane fraction |
MGI:MGI:4417868 |
ISO: Inferred from Sequence Orthology |
C |
From MGI |
|||
| GO:0005737 |
cytoplasm |
MGI:MGI:3608100 |
IDA: Inferred from Direct Assay |
C |
From MGI |
|||
| GO:0005773 |
vacuole |
MGI:MGI:3720399 |
IDA: Inferred from Direct Assay |
C |
From MGI |
|||
| GO:0005886 |
plasma membrane |
MGI:MGI:4417868 |
ISO: Inferred from Sequence Orthology |
C |
From MGI |
|||
| GO:0006468 |
protein phosphorylation |
MGI:MGI:2152098 |
IEA: Inferred from Electronic Annotation |
P |
From MGI |
|||
| GO:0007030 |
Golgi organization |
MGI:MGI:4417868 |
ISO: Inferred from Sequence Orthology |
P |
From MGI |
|||
| GO:0007049 |
cell cycle |
MGI:MGI:1354194 |
IEA: Inferred from Electronic Annotation |
UniProtKB-KW:KW-0131 |
P |
From MGI |
||
| GO:0007067 |
mitosis |
MGI:MGI:2181325 |
IDA: Inferred from Direct Assay |
P |
From MGI |
|||
| GO:0007091 |
mitotic metaphase/anaphase transition |
MGI:MGI:3606716 |
IMP: Inferred from Mutant Phenotype |
MGI:MGI:2447844 |
P |
From MGI |
||
| GO:0007275 |
multicellular organismal development |
MGI:MGI:1354194 |
IEA: Inferred from Electronic Annotation |
UniProtKB-KW:KW-0217 |
P |
From MGI |
||
| GO:0007283 |
spermatogenesis |
MGI:MGI:2447488 |
IMP: Inferred from Mutant Phenotype |
MGI:MGI:2447844 |
P |
From MGI |
||
| GO:0007399 |
nervous system development |
MGI:MGI:1354194 |
IEA: Inferred from Electronic Annotation |
UniProtKB-KW:KW-0524 |
P |
From MGI |
||
| GO:0008064 |
regulation of actin polymerization or depolymerization |
MGI:MGI:4417868 |
ISO: Inferred from Sequence Orthology |
P |
From MGI |
|||
| GO:0015629 |
actin cytoskeleton |
MGI:MGI:1312975 |
IDA: Inferred from Direct Assay |
C |
From MGI |
|||
| GO:0016301 |
kinase activity |
MGI:MGI:1354194 |
IEA: Inferred from Electronic Annotation |
UniProtKB-KW:KW-0418 |
F |
From MGI |
||
| GO:0016310 |
phosphorylation |
MGI:MGI:1354194 |
IEA: Inferred from Electronic Annotation |
UniProtKB-KW:KW-0418 |
P |
From MGI |
||
| GO:0016358 |
dendrite development |
MGI:MGI:3608100 |
IMP: Inferred from Mutant Phenotype |
MGI:MGI:2447844 |
P |
From MGI |
||
| GO:0016740 |
transferase activity |
MGI:MGI:1354194 |
IEA: Inferred from Electronic Annotation |
UniProtKB-KW:KW-0808 |
F |
From MGI |
||
| GO:0016772 |
transferase activity, transferring phosphorus-containing groups |
MGI:MGI:2152098 |
IEA: Inferred from Electronic Annotation |
F |
From MGI |
|||
| GO:0017048 |
Rho GTPase binding |
MGI:MGI:4417868 |
ISO: Inferred from Sequence Orthology |
F |
From MGI |
|||
| GO:0017124 |
SH3 domain binding |
MGI:MGI:1354194 |
IEA: Inferred from Electronic Annotation |
UniProtKB-KW:KW-0729 |
F |
From MGI |
||
| GO:0030154 |
cell differentiation |
MGI:MGI:1354194 |
IEA: Inferred from Electronic Annotation |
UniProtKB-KW:KW-0221 |
P |
From MGI |
||
| GO:0031985 |
Golgi cisterna |
MGI:MGI:4417868 |
ISO: Inferred from Sequence Orthology |
C |
From MGI |
|||
| GO:0033205 |
cell cycle cytokinesis |
MGI:MGI:4834177 |
ISO: Inferred from Sequence Orthology |
P |
From MGI |
|||
| GO:0035556 |
intracellular signal transduction |
MGI:MGI:2152098 |
IEA: Inferred from Electronic Annotation |
P |
From MGI |
|||
| GO:0043025 |
neuronal cell body |
MGI:MGI:4417868 |
ISO: Inferred from Sequence Orthology |
C |
From MGI |
|||
| GO:0045665 |
negative regulation of neuron differentiation |
MGI:MGI:3720399 |
ISO: Inferred from Sequence Orthology |
P |
From MGI |
|||
| GO:0046872 |
metal ion binding |
MGI:MGI:1354194 |
IEA: Inferred from Electronic Annotation |
UniProtKB-KW:KW-0479 |
F |
From MGI |
||
| GO:0048699 |
generation of neurons |
MGI:MGI:2181325 |
IDA: Inferred from Direct Assay |
P |
From MGI |
|||
| GO:0050774 |
negative regulation of dendrite morphogenesis |
MGI:MGI:3608100 |
IDA: Inferred from Direct Assay |
P |
From MGI |
|||
| GO:0050790 |
regulation of catalytic activity |
MGI:MGI:2152098 |
IEA: Inferred from Electronic Annotation |
P |
From MGI |
|||
| GO:0051301 |
cell division |
MGI:MGI:1354194 |
IEA: Inferred from Electronic Annotation |
UniProtKB-KW:KW-0132 |
P |
From MGI |
| |
| edit table |
Notes
References
See Help:References for how to manage references in GONUTS.
- ↑ 1.0 1.1 LoTurco JJ et al. (2003) Citron kinase is a regulator of mitosis and neurogenic cytokinesis in the neocortical ventricular zone. Cereb Cortex 13: 588-91 PubMed GONUTS page
- ↑ 2.0 2.1 2.2 Di Cunto F et al. (2000) Defective neurogenesis in citron kinase knockout mice by altered cytokinesis and massive apoptosis. Neuron 28: 115-27 PubMed GONUTS page
- ↑ 3.0 3.1 Cunto FD et al. (2002) Essential role of citron kinase in cytokinesis of spermatogenic precursors. J Cell Sci 115: 4819-26 PubMed GONUTS page
- ↑ 4.0 4.1 4.2 4.3 Di Cunto F et al. (2003) Role of citron kinase in dendritic morphogenesis of cortical neurons. Brain Res Bull 60: 319-27 PubMed GONUTS page
- ↑ 5.0 5.1 Di Cunto F et al. (1998) Citron rho-interacting kinase, a novel tissue-specific ser/thr kinase encompassing the Rho-Rac-binding protein Citron. J Biol Chem 273: 29706-11 PubMed GONUTS page
- ↑ Schmahl J et al. (2007) PDGF signaling specificity is mediated through multiple immediate early genes. Nat Genet 39: 52-60 PubMed GONUTS page
- ↑ Madaule P et al. (1995) A novel partner for the GTP-bound forms of rho and rac. FEBS Lett 377: 243-8 PubMed GONUTS page
- ↑ 8.0 8.1 Berto G et al. (2007) The Down syndrome critical region protein TTC3 inhibits neuronal differentiation via RhoA and Citron kinase. J Cell Sci 120: 1859-67 PubMed GONUTS page
