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MGI:Chrnb4
Contents |
| Species (Taxon ID) | Mus musculus (house mouse) (taxon:10090) | |
| Gene Name(s) | Chrnb4 ( synonyms: Acrb-4, Acrb4 ) | |
| Protein Name(s) | cholinergic receptor, nicotinic, beta polypeptide 4, | |
| External Links | ||
| MGI | MGI:87892 | |
Annotations
| Qualifier | GO ID | GO term name | Reference | Evidence Code | with/from | Aspect | Notes | Status |
|---|---|---|---|---|---|---|---|---|
| GO:0001508 |
regulation of action potential |
MGI:MGI:2156010 |
IGI: Inferred from Genetic Interaction |
MGI:MGI:87891 |
P |
From MGI |
||
| GO:0004872 |
receptor activity |
MGI:MGI:1354194 |
IEA: Inferred from Electronic Annotation |
UniProtKB-KW:KW-0675 |
F |
From MGI |
||
| GO:0004889 |
acetylcholine-activated cation-selective channel activity |
MGI:MGI:2152098 |
IEA: Inferred from Electronic Annotation |
F |
From MGI |
|||
| GO:0005216 |
ion channel activity |
MGI:MGI:1354194 |
IEA: Inferred from Electronic Annotation |
UniProtKB-KW:KW-0407 |
F |
From MGI |
||
| GO:0005216 |
ion channel activity |
MGI:MGI:2152098 |
IEA: Inferred from Electronic Annotation |
F |
From MGI |
|||
| GO:0005230 |
extracellular ligand-gated ion channel activity |
MGI:MGI:2152098 |
IEA: Inferred from Electronic Annotation |
F |
From MGI |
|||
| GO:0005886 |
plasma membrane |
MGI:MGI:3848633 |
ISO: Inferred from Sequence Orthology |
C |
From MGI |
|||
| GO:0005892 |
acetylcholine-gated channel complex |
MGI:MGI:4417868 |
ISO: Inferred from Sequence Orthology |
C |
From MGI |
|||
| GO:0005892 |
acetylcholine-gated channel complex |
MGI:MGI:4834177 |
ISO: Inferred from Sequence Orthology |
C |
From MGI |
|||
| GO:0006810 |
transport |
MGI:MGI:1354194 |
IEA: Inferred from Electronic Annotation |
UniProtKB-KW:KW-0813 |
P |
From MGI |
||
| GO:0006810 |
transport |
MGI:MGI:2152098 |
IEA: Inferred from Electronic Annotation |
P |
From MGI |
|||
| GO:0006811 |
ion transport |
MGI:MGI:1354194 |
IEA: Inferred from Electronic Annotation |
UniProtKB-KW:KW-0406 |
P |
From MGI |
||
| GO:0006811 |
ion transport |
MGI:MGI:2152098 |
IEA: Inferred from Electronic Annotation |
InterPro:IPR006201 |
P |
From MGI |
||
| GO:0006812 |
cation transport |
MGI:MGI:2152098 |
IEA: Inferred from Electronic Annotation |
P |
From MGI |
|||
| GO:0006939 |
smooth muscle contraction |
MGI:MGI:2156010 |
IGI: Inferred from Genetic Interaction |
MGI:MGI:87891 |
P |
From MGI |
||
| GO:0006940 |
regulation of smooth muscle contraction |
MGI:MGI:3607823 |
IMP: Inferred from Mutant Phenotype |
MGI:MGI:2158716 |
P |
From MGI |
||
| GO:0007165 |
signal transduction |
MGI:MGI:4834177 |
ISO: Inferred from Sequence Orthology |
P |
From MGI |
|||
| GO:0007626 |
locomotory behavior |
MGI:MGI:3574721 |
IMP: Inferred from Mutant Phenotype |
MGI:MGI:2158716 |
P |
From MGI |
||
| GO:0015464 |
acetylcholine receptor activity |
MGI:MGI:4834177 |
ISO: Inferred from Sequence Orthology |
F |
From MGI |
|||
| GO:0016020 |
membrane |
MGI:MGI:1354194 |
IEA: Inferred from Electronic Annotation |
UniProtKB-KW:KW-0472 |
C |
From MGI |
||
| GO:0016020 |
membrane |
MGI:MGI:2152098 |
IEA: Inferred from Electronic Annotation |
C |
From MGI |
|||
| GO:0016021 |
integral to membrane |
MGI:MGI:1354194 |
IEA: Inferred from Electronic Annotation |
UniProtKB-KW:KW-0812 |
C |
From MGI |
||
| GO:0016021 |
integral to membrane |
MGI:MGI:2152098 |
IEA: Inferred from Electronic Annotation |
C |
From MGI |
|||
| GO:0019717 |
synaptosome |
MGI:MGI:4417868 |
ISO: Inferred from Sequence Orthology |
C |
From MGI |
|||
| GO:0030054 |
cell junction |
MGI:MGI:1354194 |
IEA: Inferred from Electronic Annotation |
UniProtKB-KW:KW-0965 |
C |
From MGI |
||
| GO:0034220 |
ion transmembrane transport |
MGI:MGI:1354194 |
IEA: Inferred from Electronic Annotation |
UniProtKB-KW:KW-0407 |
P |
From MGI |
||
| GO:0034220 |
ion transmembrane transport |
MGI:MGI:2152098 |
IEA: Inferred from Electronic Annotation |
P |
From MGI |
|||
| GO:0035094 |
response to nicotine |
MGI:MGI:2156010 |
IGI: Inferred from Genetic Interaction |
MGI:MGI:87891 |
P |
From MGI |
||
| GO:0035095 |
behavioral response to nicotine |
MGI:MGI:3530984 |
IMP: Inferred from Mutant Phenotype |
MGI:MGI:2158716 |
P |
From MGI |
||
| GO:0035095 |
behavioral response to nicotine |
MGI:MGI:3574721 |
IMP: Inferred from Mutant Phenotype |
MGI:MGI:2158716 |
P |
From MGI |
||
| GO:0042166 |
acetylcholine binding |
MGI:MGI:4417868 |
ISO: Inferred from Sequence Orthology |
F |
From MGI |
|||
| GO:0042391 |
regulation of membrane potential |
MGI:MGI:2156010 |
IGI: Inferred from Genetic Interaction |
MGI:MGI:87891 |
P |
From MGI |
||
| GO:0045202 |
synapse |
MGI:MGI:1354194 |
IEA: Inferred from Electronic Annotation |
UniProtKB-KW:KW-0770 |
C |
From MGI |
||
| GO:0045211 |
postsynaptic membrane |
MGI:MGI:1354194 |
IEA: Inferred from Electronic Annotation |
UniProtKB-KW:KW-0628 |
C |
From MGI |
||
| GO:0045211 |
postsynaptic membrane |
MGI:MGI:2152098 |
IEA: Inferred from Electronic Annotation |
C |
From MGI |
|||
| GO:0060084 |
synaptic transmission involved in micturition |
MGI:MGI:2156010 |
IGI: Inferred from Genetic Interaction |
MGI:MGI:87891 |
P |
From MGI |
||
| GO:0060084 |
synaptic transmission involved in micturition |
MGI:MGI:3607823 |
IMP: Inferred from Mutant Phenotype |
MGI:MGI:2158716 |
P |
From MGI |
||
| GO:0060084 |
synaptic transmission involved in micturition |
MGI:MGI:4834177 |
ISO: Inferred from Sequence Orthology |
P |
From MGI |
| ||
| edit table |
Notes
References
See Help:References for how to manage references in GONUTS.
- ↑ 1.0 1.1 1.2 1.3 1.4 Xu W et al. (1999) Multiorgan autonomic dysfunction in mice lacking the beta2 and the beta4 subunits of neuronal nicotinic acetylcholine receptors. J Neurosci 19: 9298-305 PubMed GONUTS page
- ↑ Rezvani K et al. (2009) UBXD4, a UBX-containing protein, regulates the cell surface number and stability of alpha3-containing nicotinic acetylcholine receptors. J Neurosci 29: 6883-96 PubMed GONUTS page
- ↑ 3.0 3.1 De Biasi M et al. (2000) Nicotinic acetylcholine receptors in the autonomic control of bladder function. Eur J Pharmacol 393: 137-40 PubMed GONUTS page
- ↑ 4.0 4.1 Salas R et al. (2004) The alpha3 and beta4 nicotinic acetylcholine receptor subunits are necessary for nicotine-induced seizures and hypolocomotion in mice. Neuropharmacology 47: 401-7 PubMed GONUTS page
- ↑ Salas R et al. (2004) Decreased signs of nicotine withdrawal in mice null for the beta4 nicotinic acetylcholine receptor subunit. J Neurosci 24: 10035-9 PubMed GONUTS page