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MGI:Chrna1
Contents |
| Species (Taxon ID) | Mus musculus (house mouse) (taxon:10090) | |
| Gene Name(s) | Chrna1 ( synonyms: Achr-1, Acra ) | |
| Protein Name(s) | cholinergic receptor, nicotinic, alpha polypeptide 1 (muscle), | |
| External Links | ||
| MGI | MGI:87885 | |
Annotations
| Qualifier | GO ID | GO term name | Reference | Evidence Code | with/from | Aspect | Notes | Status |
|---|---|---|---|---|---|---|---|---|
| GO:0003009 |
skeletal muscle contraction |
MGI:MGI:4834177 |
ISO: Inferred from Sequence Orthology |
P |
From MGI |
|||
| GO:0004872 |
receptor activity |
MGI:MGI:1354194 |
IEA: Inferred from Electronic Annotation |
UniProtKB-KW:KW-0675 |
F |
From MGI |
||
| GO:0004889 |
acetylcholine-activated cation-selective channel activity |
MGI:MGI:2154458 |
ISO: Inferred from Sequence Orthology |
F |
From MGI |
|||
| GO:0004889 |
acetylcholine-activated cation-selective channel activity |
MGI:MGI:4417868 |
ISO: Inferred from Sequence Orthology |
F |
From MGI |
|||
| GO:0005216 |
ion channel activity |
MGI:MGI:1354194 |
IEA: Inferred from Electronic Annotation |
UniProtKB-KW:KW-0407 |
F |
From MGI |
||
| GO:0005216 |
ion channel activity |
MGI:MGI:2152098 |
IEA: Inferred from Electronic Annotation |
F |
From MGI |
|||
| GO:0005230 |
extracellular ligand-gated ion channel activity |
MGI:MGI:2152098 |
IEA: Inferred from Electronic Annotation |
F |
From MGI |
|||
| GO:0005886 |
plasma membrane |
MGI:MGI:2388930 |
IDA: Inferred from Direct Assay |
C |
From MGI |
|||
| GO:0005892 |
acetylcholine-gated channel complex |
MGI:MGI:83925 |
IPI: Inferred from Physical Interaction |
C |
From MGI |
|||
| GO:0006810 |
transport |
MGI:MGI:1354194 |
IEA: Inferred from Electronic Annotation |
UniProtKB-KW:KW-0813 |
P |
From MGI |
||
| GO:0006810 |
transport |
MGI:MGI:2152098 |
IEA: Inferred from Electronic Annotation |
P |
From MGI |
|||
| GO:0006811 |
ion transport |
MGI:MGI:1354194 |
IEA: Inferred from Electronic Annotation |
UniProtKB-KW:KW-0406 |
P |
From MGI |
||
| GO:0006811 |
ion transport |
MGI:MGI:2152098 |
IEA: Inferred from Electronic Annotation |
InterPro:IPR006201 |
P |
From MGI |
||
| GO:0007274 |
neuromuscular synaptic transmission |
MGI:MGI:2154458 |
ISO: Inferred from Sequence Orthology |
P |
From MGI |
|||
| GO:0007528 |
neuromuscular junction development |
MGI:MGI:2154458 |
ISO: Inferred from Sequence Orthology |
P |
From MGI |
|||
| GO:0009986 |
cell surface |
MGI:MGI:4834177 |
ISO: Inferred from Sequence Orthology |
C |
From MGI |
|||
| GO:0016020 |
membrane |
MGI:MGI:1354194 |
IEA: Inferred from Electronic Annotation |
UniProtKB-KW:KW-0472 |
C |
From MGI |
||
| GO:0016020 |
membrane |
MGI:MGI:2152098 |
IEA: Inferred from Electronic Annotation |
C |
From MGI |
|||
| GO:0016021 |
integral to membrane |
MGI:MGI:1354194 |
IEA: Inferred from Electronic Annotation |
UniProtKB-KW:KW-0812 |
C |
From MGI |
||
| GO:0016021 |
integral to membrane |
MGI:MGI:2152098 |
IEA: Inferred from Electronic Annotation |
C |
From MGI |
|||
| GO:0019228 |
regulation of action potential in neuron |
MGI:MGI:4834177 |
ISO: Inferred from Sequence Orthology |
P |
From MGI |
|||
| GO:0030054 |
cell junction |
MGI:MGI:1354194 |
IEA: Inferred from Electronic Annotation |
UniProtKB-KW:KW-0965 |
C |
From MGI |
||
| GO:0031594 |
neuromuscular junction |
MGI:MGI:2154458 |
ISO: Inferred from Sequence Orthology |
C |
From MGI |
|||
| GO:0031594 |
neuromuscular junction |
MGI:MGI:3607648 |
IDA: Inferred from Direct Assay |
C |
From MGI |
|||
| GO:0034220 |
ion transmembrane transport |
MGI:MGI:1354194 |
IEA: Inferred from Electronic Annotation |
UniProtKB-KW:KW-0407 |
P |
From MGI |
||
| GO:0034220 |
ion transmembrane transport |
MGI:MGI:2152098 |
IEA: Inferred from Electronic Annotation |
P |
From MGI |
|||
| GO:0042391 |
regulation of membrane potential |
MGI:MGI:2154458 |
ISO: Inferred from Sequence Orthology |
P |
From MGI |
|||
| GO:0042391 |
regulation of membrane potential |
MGI:MGI:67940 |
IGI: Inferred from Genetic Interaction |
MGI:MGI:87894 |
P |
From MGI |
||
| GO:0045202 |
synapse |
MGI:MGI:1354194 |
IEA: Inferred from Electronic Annotation |
UniProtKB-KW:KW-0770 |
C |
From MGI |
||
| GO:0045211 |
postsynaptic membrane |
MGI:MGI:1354194 |
IEA: Inferred from Electronic Annotation |
UniProtKB-KW:KW-0628 |
C |
From MGI |
||
| GO:0045211 |
postsynaptic membrane |
MGI:MGI:2152098 |
IEA: Inferred from Electronic Annotation |
C |
From MGI |
|||
| GO:0046716 |
muscle cell homeostasis |
MGI:MGI:4834177 |
ISO: Inferred from Sequence Orthology |
P |
From MGI |
|||
| GO:0048630 |
skeletal muscle tissue growth |
MGI:MGI:4834177 |
ISO: Inferred from Sequence Orthology |
P |
From MGI |
|||
| GO:0050881 |
musculoskeletal movement |
MGI:MGI:4834177 |
ISO: Inferred from Sequence Orthology |
P |
From MGI |
|||
| GO:0050905 |
neuromuscular process |
MGI:MGI:4834177 |
ISO: Inferred from Sequence Orthology |
P |
From MGI |
|||
| GO:0070050 |
neuron homeostasis |
MGI:MGI:4834177 |
ISO: Inferred from Sequence Orthology |
P |
From MGI |
|||
|
contributes_to |
GO:0004889 |
acetylcholine-activated cation-selective channel activity |
MGI:MGI:67940 |
IGI: Inferred from Genetic Interaction |
MGI:MGI:87894 |
F |
From MGI |
|
|
contributes_to |
GO:0015464 |
acetylcholine receptor activity |
MGI:MGI:3799559 |
IDA: Inferred from Direct Assay |
F |
From MGI |
||
|
contributes_to |
GO:0042166 |
acetylcholine binding |
MGI:MGI:83925 |
IGI: Inferred from Genetic Interaction |
MGI:MGI:87893 |
F |
From MGI |
|
| edit table |
Notes
References
See Help:References for how to manage references in GONUTS.
- ↑ Marchand S et al. (2002) Rapsyn escorts the nicotinic acetylcholine receptor along the exocytic pathway via association with lipid rafts. J Neurosci 22: 8891-901 PubMed GONUTS page
- ↑ 2.0 2.1 Wang ZZ et al. (1996) Assembly of the nicotinic acetylcholine receptor. The first transmembrane domains of truncated alpha and delta subunits are required for heterodimer formation in vivo. J Biol Chem 271: 27575-84 PubMed GONUTS page
- ↑ Fu AK et al. (2005) Aberrant motor axon projection, acetylcholine receptor clustering, and neurotransmission in cyclin-dependent kinase 5 null mice. Proc Natl Acad Sci U S A 102: 15224-9 PubMed GONUTS page
- ↑ 4.0 4.1 Gu Y et al. (1990) Properties of embryonic and adult muscle acetylcholine receptors transiently expressed in COS cells. Neuron 5: 147-57 PubMed GONUTS page
- ↑ Engel AG et al. (1996) New mutations in acetylcholine receptor subunit genes reveal heterogeneity in the slow-channel congenital myasthenic syndrome. Hum Mol Genet 5: 1217-27 PubMed GONUTS page
