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MGI:Chl1
Contents |
| Species (Taxon ID) | Mus musculus (house mouse) (taxon:10090) | |
| Gene Name(s) | Chl1 ( synonyms: CALL, close homolog of L1, LICAM2 ) | |
| Protein Name(s) | cell adhesion molecule with homology to L1CAM, | |
| External Links | ||
| MGI | MGI:1098266 | |
Annotations
| Qualifier | GO ID | GO term name | Reference | Evidence Code | with/from | Aspect | Notes | Status |
|---|---|---|---|---|---|---|---|---|
| GO:0001764 |
neuron migration |
MGI:MGI:3530933 |
IMP: Inferred from Mutant Phenotype |
MGI:MGI:2429688 |
P |
From MGI |
||
| GO:0002020 |
protease binding |
MGI:MGI:3040545 |
IPI: Inferred from Physical Interaction |
F |
From MGI |
|||
| GO:0005576 |
extracellular region |
MGI:MGI:1354194 |
IEA: Inferred from Electronic Annotation |
UniProtKB-KW:KW-0964 |
C |
From MGI |
||
| GO:0005578 |
proteinaceous extracellular matrix |
MGI:MGI:1354194 |
IEA: Inferred from Electronic Annotation |
UniProtKB-KW:KW-0272 |
C |
From MGI |
||
| GO:0005886 |
plasma membrane |
MGI:MGI:1354194 |
IEA: Inferred from Electronic Annotation |
UniProtKB-KW:KW-1003 |
C |
From MGI |
||
| GO:0007155 |
cell adhesion |
MGI:MGI:1354194 |
IEA: Inferred from Electronic Annotation |
UniProtKB-KW:KW-0130 |
P |
From MGI |
||
| GO:0007275 |
multicellular organismal development |
MGI:MGI:1354194 |
IEA: Inferred from Electronic Annotation |
UniProtKB-KW:KW-0217 |
P |
From MGI |
||
| GO:0007399 |
nervous system development |
MGI:MGI:1354194 |
IEA: Inferred from Electronic Annotation |
UniProtKB-KW:KW-0524 |
P |
From MGI |
||
| GO:0007411 |
axon guidance |
MGI:MGI:2389546 |
IMP: Inferred from Mutant Phenotype |
MGI:MGI:2429688 |
P |
From MGI |
||
| GO:0007610 |
behavior |
MGI:MGI:2389546 |
IMP: Inferred from Mutant Phenotype |
MGI:MGI:2429688 |
P |
From MGI |
||
| GO:0008344 |
adult locomotory behavior |
MGI:MGI:3529715 |
IMP: Inferred from Mutant Phenotype |
MGI:MGI:2429688 |
P |
From MGI |
||
| GO:0016020 |
membrane |
MGI:MGI:1354194 |
IEA: Inferred from Electronic Annotation |
UniProtKB-KW:KW-0472 |
C |
From MGI |
||
| GO:0016021 |
integral to membrane |
MGI:MGI:1354194 |
IEA: Inferred from Electronic Annotation |
UniProtKB-KW:KW-0812 |
C |
From MGI |
||
| GO:0030154 |
cell differentiation |
MGI:MGI:1354194 |
IEA: Inferred from Electronic Annotation |
UniProtKB-KW:KW-0221 |
P |
From MGI |
||
| GO:0030425 |
dendrite |
MGI:MGI:3530933 |
IDA: Inferred from Direct Assay |
C |
From MGI |
|||
| GO:0031175 |
neuron projection development |
MGI:MGI:1339859 |
IDA: Inferred from Direct Assay |
P |
From MGI |
|||
| GO:0043524 |
negative regulation of neuron apoptotic process |
MGI:MGI:3040545 |
IDA: Inferred from Direct Assay |
P |
From MGI |
|||
| GO:0045177 |
apical part of cell |
MGI:MGI:3530933 |
IDA: Inferred from Direct Assay |
C |
From MGI |
|||
| GO:0050890 |
cognition |
MGI:MGI:3529715 |
IMP: Inferred from Mutant Phenotype |
MGI:MGI:2429688 |
P |
From MGI |
||
|
NOT |
GO:0007156 |
homophilic cell adhesion |
MGI:MGI:1339859 |
IDA: Inferred from Direct Assay |
P |
From MGI |
| |
| edit table |
Notes
References
See Help:References for how to manage references in GONUTS.
- ↑ 1.0 1.1 1.2 Demyanenko GP et al. (2004) Close homolog of L1 modulates area-specific neuronal positioning and dendrite orientation in the cerebral cortex. Neuron 44: 423-37 PubMed GONUTS page
- ↑ 2.0 2.1 Naus S et al. (2004) Ectodomain shedding of the neural recognition molecule CHL1 by the metalloprotease-disintegrin ADAM8 promotes neurite outgrowth and suppresses neuronal cell death. J Biol Chem 279: 16083-90 PubMed GONUTS page
- ↑ 3.0 3.1 Montag-Sallaz M et al. (2002) Misguided axonal projections, neural cell adhesion molecule 180 mRNA upregulation, and altered behavior in mice deficient for the close homolog of L1. Mol Cell Biol 22: 7967-81 PubMed GONUTS page
- ↑ 4.0 4.1 Pratte M et al. (2003) Mice deficient for the close homologue of the neural adhesion cell L1 (CHL1) display alterations in emotional reactivity and motor coordination. Behav Brain Res 147: 31-9 PubMed GONUTS page
- ↑ 5.0 5.1 Hillenbrand R et al. (1999) The close homologue of the neural adhesion molecule L1 (CHL1): patterns of expression and promotion of neurite outgrowth by heterophilic interactions. Eur J Neurosci 11: 813-26 PubMed GONUTS page
