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MGI:Chat

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Contents

Species (Taxon ID) Mus musculus (house mouse) (taxon:10090)
Gene Name(s) Chat
Protein Name(s) choline acetyltransferase,
External Links
MGI MGI:88392

Annotations

Qualifier GO ID GO term name Reference Evidence Code with/from Aspect Notes Status
GO:0004102

choline O-acetyltransferase activity

MGI:MGI:2449890
PMID:12533614[1]

IMP: Inferred from Mutant Phenotype

MGI:MGI:2450310

F

From MGI

GO:0004102

choline O-acetyltransferase activity

MGI:MGI:3045889
PMID:12441053[2]

IMP: Inferred from Mutant Phenotype

MGI:MGI:3045900

F

From MGI

GO:0004102

choline O-acetyltransferase activity

MGI:MGI:4417868

ISO: Inferred from Sequence Orthology

UniProtKB:P32738

F

From MGI

GO:0005625

soluble fraction

MGI:MGI:4417868

ISO: Inferred from Sequence Orthology

UniProtKB:P32738

C

From MGI

GO:0005739

mitochondrion

MGI:MGI:3852644
PMID:18614015[3]

IDA: Inferred from Direct Assay

C

From MGI

GO:0007268

synaptic transmission

MGI:MGI:2449890
PMID:12533614[1]

IMP: Inferred from Mutant Phenotype

MGI:MGI:2450310

P

From MGI

GO:0007274

neuromuscular synaptic transmission

MGI:MGI:3045889
PMID:12441053[2]

IMP: Inferred from Mutant Phenotype

MGI:MGI:3045900

P

From MGI

GO:0007517

muscle organ development

MGI:MGI:3045889
PMID:12441053[2]

IMP: Inferred from Mutant Phenotype

MGI:MGI:3045900

P

From MGI

GO:0007529

establishment of synaptic specificity at neuromuscular junction

MGI:MGI:2449890
PMID:12533614[1]

IMP: Inferred from Mutant Phenotype

MGI:MGI:2450310

P

From MGI

GO:0007613

memory

MGI:MGI:4417868

ISO: Inferred from Sequence Orthology

UniProtKB:P32738

P

From MGI

GO:0007622

rhythmic behavior

MGI:MGI:3577822
PMID:15820692[4]

IMP: Inferred from Mutant Phenotype

MGI:MGI:2450310

P

From MGI

GO:0007628

adult walking behavior

MGI:MGI:3577822
PMID:15820692[4]

IMP: Inferred from Mutant Phenotype

MGI:MGI:2450310

P

From MGI

GO:0008292

acetylcholine biosynthetic process

MGI:MGI:4417868

ISO: Inferred from Sequence Orthology

UniProtKB:P32738

P

From MGI

GO:0016358

dendrite development

MGI:MGI:3045889
PMID:12441053[2]

IMP: Inferred from Mutant Phenotype

MGI:MGI:3045900

P

From MGI

GO:0016740

transferase activity

MGI:MGI:1354194

IEA: Inferred from Electronic Annotation

UniProtKB-KW:KW-0808

F

From MGI

GO:0016746

transferase activity, transferring acyl groups

MGI:MGI:1354194

IEA: Inferred from Electronic Annotation

UniProtKB-KW:KW-0012

F

From MGI

GO:0019717

synaptosome

MGI:MGI:4417868

ISO: Inferred from Sequence Orthology

UniProtKB:P32738

C

From MGI

GO:0030182

neuron differentiation

MGI:MGI:3045889
PMID:12441053[2]

IMP: Inferred from Mutant Phenotype

MGI:MGI:3045900

P

From MGI

GO:0030424

axon

MGI:MGI:4398759
PMID:19906978[5]

IDA: Inferred from Direct Assay

C

From MGI

GO:0033265

choline binding

MGI:MGI:4417868

ISO: Inferred from Sequence Orthology

UniProtKB:P32738

F

From MGI

GO:0043005

neuron projection

MGI:MGI:2181838
PMID:12115678[6]

IDA: Inferred from Direct Assay

C

From MGI

GO:0043025

neuronal cell body

MGI:MGI:1306999
PMID:9853118[7]

IDA: Inferred from Direct Assay

C

From MGI

GO:0043179

rhythmic excitation

MGI:MGI:3577822
PMID:15820692[4]

IMP: Inferred from Mutant Phenotype

MGI:MGI:2450310

P

From MGI


Notes

References

See Help:References for how to manage references in GONUTS.
  1. 1.0 1.1 1.2 Brandon EP et al. (2003) Aberrant patterning of neuromuscular synapses in choline acetyltransferase-deficient mice. J Neurosci 23: 539-49 PubMed GONUTS page
  2. 2.0 2.1 2.2 2.3 2.4 Misgeld T et al. (2002) Roles of neurotransmitter in synapse formation: development of neuromuscular junctions lacking choline acetyltransferase. Neuron 36: 635-48 PubMed GONUTS page
  3. Pagliarini DJ et al. (2008) A mitochondrial protein compendium elucidates complex I disease biology. Cell 134: 112-23 PubMed GONUTS page
  4. 4.0 4.1 4.2 Myers CP et al. (2005) Cholinergic input is required during embryonic development to mediate proper assembly of spinal locomotor circuits. Neuron 46: 37-49 PubMed GONUTS page
  5. Quina LA et al. (2009) Brn3a and Nurr1 mediate a gene regulatory pathway for habenula development. J Neurosci 29: 14309-22 PubMed GONUTS page
  6. Meade CA et al. (2002) Cellular localization and development of neuronal intranuclear inclusions in striatal and cortical neurons in R6/2 transgenic mice. J Comp Neurol 449: 241-69 PubMed GONUTS page
  7. Sang Q & Young HM (1998) The origin and development of the vagal and spinal innervation of the external muscle of the mouse esophagus. Brain Res 809: 253-68 PubMed GONUTS page
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