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MGI:Cflar

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Contents

Species (Taxon ID) Mus musculus (house mouse) (taxon:10090)
Gene Name(s) Cflar ( synonyms: c-Flip, Cash, Casper, Flip )
Protein Name(s) CASP8 and FADD-like apoptosis regulator,
External Links
MGI MGI:1336166

Annotations

Qualifier GO ID GO term name Reference Evidence Code with/from Aspect Notes Status
GO:0004197

cysteine-type endopeptidase activity

MGI:MGI:2152098

IEA: Inferred from Electronic Annotation

InterPro:IPR011600
InterPro:IPR001309
InterPro:IPR002398

F

From MGI

GO:0005737

cytoplasm

MGI:MGI:3612311
PMID:16263940[1]

IDA: Inferred from Direct Assay

C

From MGI

GO:0005737

cytoplasm

MGI:MGI:4834177

ISO: Inferred from Sequence Orthology

UniProtKB:O15519

C

From MGI

GO:0006508

proteolysis

MGI:MGI:2152098

IEA: Inferred from Electronic Annotation

InterPro:IPR011600
InterPro:IPR001309
InterPro:IPR002398

P

From MGI

GO:0006915

apoptotic process

MGI:MGI:2665373
PMID:12819136[2]

RCA: Inferred from Reviewed Computational Analysis

P

From MGI

GO:0006916

anti-apoptosis

MGI:MGI:4417868

ISO: Inferred from Sequence Orthology

NCBI:NP_001029036

P

From MGI

GO:0006916

anti-apoptosis

MGI:MGI:4834177

ISO: Inferred from Sequence Orthology

UniProtKB:O15519

P

From MGI

GO:0008234

cysteine-type peptidase activity

MGI:MGI:2152098

IEA: Inferred from Electronic Annotation

InterPro:IPR015917

F

From MGI

GO:0031264

death-inducing signaling complex

MGI:MGI:4834177

ISO: Inferred from Sequence Orthology

UniProtKB:O15519

C

From MGI

GO:0031265

CD95 death-inducing signaling complex

MGI:MGI:4417868

ISO: Inferred from Sequence Orthology

NCBI:NP_001029036

C

From MGI

GO:0042981

regulation of apoptotic process

MGI:MGI:2665373
PMID:12819136[2]

RCA: Inferred from Reviewed Computational Analysis

P

From MGI

GO:0043066

negative regulation of apoptotic process

MGI:MGI:3612311
PMID:16263940[1]

IMP: Inferred from Mutant Phenotype

P

From MGI

GO:0043154

negative regulation of cysteine-type endopeptidase activity involved in apoptotic process

MGI:MGI:3612311
PMID:16263940[1]

IMP: Inferred from Mutant Phenotype

P

From MGI

GO:2001237

negative regulation of extrinsic apoptotic signaling pathway

MGI:MGI:4834177

ISO: Inferred from Sequence Orthology

UniProtKB:O15519

P

From MGI


Notes

References

See Help:References for how to manage references in GONUTS.
  1. 1.0 1.1 1.2 Giampietri C et al. (2006) c-Flip expression and function in fetal mouse gonocytes. FASEB J 20: 124-6 PubMed GONUTS page
  2. 2.0 2.1 Reed JC et al. (2003) Comparative analysis of apoptosis and inflammation genes of mice and humans. Genome Res 13: 1376-88 PubMed GONUTS page
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