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MGI:Cfl1
Contents |
| Species (Taxon ID) | Mus musculus (house mouse) (taxon:10090) | |
| Gene Name(s) | Cfl1 ( synonyms: Cof, cofilin ) | |
| Protein Name(s) | cofilin 1, non-muscle, | |
| External Links | ||
| MGI | MGI:101757 | |
Annotations
| Qualifier | GO ID | GO term name | Reference | Evidence Code | with/from | Aspect | Notes | Status |
|---|---|---|---|---|---|---|---|---|
| GO:0000910 |
cytokinesis |
MGI:MGI:3575233 |
IMP: Inferred from Mutant Phenotype |
P |
From MGI |
|||
| GO:0001755 |
neural crest cell migration |
MGI:MGI:3530675 |
IMP: Inferred from Mutant Phenotype |
MGI:MGI:3574399 |
P |
From MGI |
||
| GO:0001842 |
neural fold formation |
MGI:MGI:3530675 |
IMP: Inferred from Mutant Phenotype |
MGI:MGI:3574399 |
P |
From MGI |
||
| GO:0003779 |
actin binding |
MGI:MGI:4417868 |
ISO: Inferred from Sequence Orthology |
F |
From MGI |
|||
| GO:0005622 |
intracellular |
MGI:MGI:2152098 |
IEA: Inferred from Electronic Annotation |
C |
From MGI |
|||
| GO:0005634 |
nucleus |
MGI:MGI:1354194 |
IEA: Inferred from Electronic Annotation |
UniProtKB-KW:KW-0539 |
C |
From MGI |
||
| GO:0005737 |
cytoplasm |
MGI:MGI:3575233 |
IDA: Inferred from Direct Assay |
C |
From MGI |
|||
| GO:0005737 |
cytoplasm |
MGI:MGI:4417868 |
ISO: Inferred from Sequence Orthology |
C |
From MGI |
|||
| GO:0005856 |
cytoskeleton |
MGI:MGI:1354194 |
IEA: Inferred from Electronic Annotation |
UniProtKB-KW:KW-0206 |
C |
From MGI |
||
| GO:0005886 |
plasma membrane |
MGI:MGI:1354194 |
IEA: Inferred from Electronic Annotation |
UniProtKB-KW:KW-1003 |
C |
From MGI |
||
| GO:0006468 |
protein phosphorylation |
MGI:MGI:3692803 |
IDA: Inferred from Direct Assay |
P |
From MGI |
|||
| GO:0006606 |
protein import into nucleus |
MGI:MGI:4417868 |
ISO: Inferred from Sequence Orthology |
P |
From MGI |
|||
| GO:0006928 |
cellular component movement |
MGI:MGI:3575233 |
IMP: Inferred from Mutant Phenotype |
P |
From MGI |
|||
| GO:0007010 |
cytoskeleton organization |
MGI:MGI:4834177 |
ISO: Inferred from Sequence Orthology |
P |
From MGI |
|||
| GO:0007015 |
actin filament organization |
MGI:MGI:3526001 |
IMP: Inferred from Mutant Phenotype |
MGI:MGI:3574399 |
P |
From MGI |
||
| GO:0016020 |
membrane |
MGI:MGI:1354194 |
IEA: Inferred from Electronic Annotation |
UniProtKB-KW:KW-0472 |
C |
From MGI |
||
| GO:0022604 |
regulation of cell morphogenesis |
MGI:MGI:4834177 |
ISO: Inferred from Sequence Orthology |
P |
From MGI |
|||
| GO:0030010 |
establishment of cell polarity |
MGI:MGI:3526001 |
IMP: Inferred from Mutant Phenotype |
MGI:MGI:3574399 |
P |
From MGI |
||
| GO:0030027 |
lamellipodium |
MGI:MGI:4417868 |
ISO: Inferred from Sequence Orthology |
C |
From MGI |
|||
| GO:0030030 |
cell projection organization |
MGI:MGI:3610880 |
ISO: Inferred from Sequence Orthology |
P |
From MGI |
|||
| GO:0030836 |
positive regulation of actin filament depolymerization |
MGI:MGI:3575233 |
IMP: Inferred from Mutant Phenotype |
P |
From MGI |
|||
| GO:0030864 |
cortical actin cytoskeleton |
MGI:MGI:3047055 |
IDA: Inferred from Direct Assay |
C |
From MGI |
|||
| GO:0030864 |
cortical actin cytoskeleton |
MGI:MGI:3575233 |
IDA: Inferred from Direct Assay |
C |
From MGI |
|||
| GO:0031252 |
cell leading edge |
MGI:MGI:4417868 |
ISO: Inferred from Sequence Orthology |
C |
From MGI |
|||
| GO:0042995 |
cell projection |
MGI:MGI:1354194 |
IEA: Inferred from Electronic Annotation |
UniProtKB-KW:KW-0966 |
C |
From MGI |
||
| GO:0043200 |
response to amino acid stimulus |
MGI:MGI:3692803 |
IDA: Inferred from Direct Assay |
P |
From MGI |
|||
| GO:0045792 |
negative regulation of cell size |
MGI:MGI:3610880 |
ISO: Inferred from Sequence Orthology |
P |
From MGI |
| ||
| edit table |
Notes
References
See Help:References for how to manage references in GONUTS.
- ↑ 1.0 1.1 1.2 1.3 1.4 Hotulainen P et al. (2005) Actin-depolymerizing factor and cofilin-1 play overlapping roles in promoting rapid F-actin depolymerization in mammalian nonmuscle cells. Mol Biol Cell 16: 649-64 PubMed GONUTS page
- ↑ 2.0 2.1 Gurniak CB et al. (2005) The actin depolymerizing factor n-cofilin is essential for neural tube morphogenesis and neural crest cell migration. Dev Biol 278: 231-41 PubMed GONUTS page
- ↑ 3.0 3.1 Offenhäuser N et al. (2006) Increased ethanol resistance and consumption in Eps8 knockout mice correlates with altered actin dynamics. Cell 127: 213-26 PubMed GONUTS page
- ↑ 4.0 4.1 Bailey CD & Johnson GV (2005) Tissue transglutaminase contributes to disease progression in the R6/2 Huntington's disease mouse model via aggregate-independent mechanisms. J Neurochem 92: 83-92 PubMed GONUTS page
- ↑ 5.0 5.1 Tavazoie SF et al. (2005) Regulation of neuronal morphology and function by the tumor suppressors Tsc1 and Tsc2. Nat Neurosci 8: 1727-34 PubMed GONUTS page
- ↑ Bertling E et al. (2004) Cyclase-associated protein 1 (CAP1) promotes cofilin-induced actin dynamics in mammalian nonmuscle cells. Mol Biol Cell 15: 2324-34 PubMed GONUTS page
