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MGI:Cfc1

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Contents

Species (Taxon ID) Mus musculus (house mouse) (taxon:10090)
Gene Name(s) Cfc1 ( synonyms: cryptic )
Protein Name(s) cripto, FRL-1, cryptic family 1,
External Links
MGI MGI:109448

Annotations

Qualifier GO ID GO term name Reference Evidence Code with/from Aspect Notes Status
GO:0001889

liver development

MGI:MGI:1346729
PMID:10521397[1]

IMP: Inferred from Mutant Phenotype

MGI:MGI:2179530

P

From MGI

GO:0001947

heart looping

MGI:MGI:1346729
PMID:10521397[1]

IMP: Inferred from Mutant Phenotype

MGI:MGI:2179530

P

From MGI

GO:0003007

heart morphogenesis

MGI:MGI:1346729
PMID:10521397[1]

IMP: Inferred from Mutant Phenotype

MGI:MGI:2179530

P

From MGI

GO:0005576

extracellular region

MGI:MGI:1354194

IEA: Inferred from Electronic Annotation

UniProtKB-KW:KW-0964

C

From MGI

GO:0005886

plasma membrane

MGI:MGI:1354194

IEA: Inferred from Electronic Annotation

UniProtKB-KW:KW-1003

C

From MGI

GO:0007275

multicellular organismal development

MGI:MGI:1354194

IEA: Inferred from Electronic Annotation

UniProtKB-KW:KW-0217

P

From MGI

GO:0007368

determination of left/right symmetry

MGI:MGI:1346729
PMID:10521397[1]

IMP: Inferred from Mutant Phenotype

MGI:MGI:2179530

P

From MGI

GO:0007369

gastrulation

MGI:MGI:1354194

IEA: Inferred from Electronic Annotation

UniProtKB-KW:KW-0306

P

From MGI

GO:0007492

endoderm development

MGI:MGI:2136711
PMID:11412024[2]

IGI: Inferred from Genetic Interaction

MGI:MGI:1857543

P

From MGI

GO:0009791

post-embryonic development

MGI:MGI:1346729
PMID:10521397[1]

IMP: Inferred from Mutant Phenotype

MGI:MGI:2179530

P

From MGI

GO:0009952

anterior/posterior pattern specification

MGI:MGI:2136711
PMID:11412024[2]

IGI: Inferred from Genetic Interaction

MGI:MGI:1857543

P

From MGI

GO:0016020

membrane

MGI:MGI:1354194

IEA: Inferred from Electronic Annotation

UniProtKB-KW:KW-0472

C

From MGI

GO:0030509

BMP signaling pathway

MGI:MGI:3703823
PMID:17360443[3]

IDA: Inferred from Direct Assay

P

From MGI

GO:0031225

anchored to membrane

MGI:MGI:1354194

IEA: Inferred from Electronic Annotation

UniProtKB-KW:KW-0336

C

From MGI

GO:0038092

nodal signaling pathway

MGI:MGI:4834177

ISO: Inferred from Sequence Orthology

UniProtKB:P0CG37

P

From MGI

GO:0038100

nodal binding

MGI:MGI:4834177

ISO: Inferred from Sequence Orthology

UniProtKB:P0CG37

F

From MGI

GO:0048536

spleen development

MGI:MGI:1346729
PMID:10521397[1]

IMP: Inferred from Mutant Phenotype

MGI:MGI:2179530

P

From MGI

GO:0048546

digestive tract morphogenesis

MGI:MGI:1346729
PMID:10521397[1]

IMP: Inferred from Mutant Phenotype

MGI:MGI:2179530

P

From MGI

GO:0048856

anatomical structure development

MGI:MGI:2136711
PMID:11412024[2]

IGI: Inferred from Genetic Interaction

MGI:MGI:1857543

P

From MGI

GO:0060070

canonical Wnt receptor signaling pathway

MGI:MGI:3703823
PMID:17360443[3]

IDA: Inferred from Direct Assay

P

From MGI

GO:0060413

atrial septum morphogenesis

MGI:MGI:1346729
PMID:10521397[1]

IMP: Inferred from Mutant Phenotype

MGI:MGI:2179530

P

From MGI

GO:0060460

left lung morphogenesis

MGI:MGI:1346729
PMID:10521397[1]

IMP: Inferred from Mutant Phenotype

MGI:MGI:2179530

P

From MGI

GO:0060541

respiratory system development

MGI:MGI:1346729
PMID:10521397[1]

IMP: Inferred from Mutant Phenotype

MGI:MGI:2179530

P

From MGI


Notes

References

See Help:References for how to manage references in GONUTS.
  1. 1.0 1.1 1.2 1.3 1.4 1.5 1.6 1.7 1.8 1.9 Yan YT et al. (1999) Conserved requirement for EGF-CFC genes in vertebrate left-right axis formation. Genes Dev 13: 2527-37 PubMed GONUTS page
  2. 2.0 2.1 2.2 Kimura C et al. (2001) Complementary functions of Otx2 and Cripto in initial patterning of mouse epiblast. Dev Biol 235: 12-32 PubMed GONUTS page
  3. 3.0 3.1 Liu Y et al. (2007) Sox17 is essential for the specification of cardiac mesoderm in embryonic stem cells. Proc Natl Acad Sci U S A 104: 3859-64 PubMed GONUTS page
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