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MGI:Cer1
Contents |
| Species (Taxon ID) | Mus musculus (house mouse) (taxon:10090) | |
| Gene Name(s) | Cer1 ( synonyms: cer-1, Cerberus-like, Cerl, Cerl1, Cerr1 ) | |
| Protein Name(s) | cerberus 1 homolog (Xenopus laevis), | |
| External Links | ||
| MGI | MGI:1201414 | |
Annotations
| Qualifier | GO ID | GO term name | Reference | Evidence Code | with/from | Aspect | Notes | Status |
|---|---|---|---|---|---|---|---|---|
| GO:0001657 |
ureteric bud development |
MGI:MGI:5308475 |
IMP: Inferred from Mutant Phenotype |
P |
From MGI |
|||
| GO:0005125 |
cytokine activity |
MGI:MGI:1354194 |
IEA: Inferred from Electronic Annotation |
UniProtKB-KW:KW-0202 |
F |
From MGI |
||
| GO:0005576 |
extracellular region |
MGI:MGI:1101446 |
IDA: Inferred from Direct Assay |
C |
From MGI |
|||
| GO:0005615 |
extracellular space |
MGI:MGI:1858315 |
IDA: Inferred from Direct Assay |
C |
From MGI |
|||
| GO:0007369 |
gastrulation |
MGI:MGI:3776330 |
IGI: Inferred from Genetic Interaction |
MGI:MGI:98658 |
P |
From MGI |
||
| GO:0007399 |
nervous system development |
MGI:MGI:4834177 |
ISO: Inferred from Sequence Orthology |
P |
From MGI |
|||
| GO:0008285 |
negative regulation of cell proliferation |
MGI:MGI:3042338 |
IGI: Inferred from Genetic Interaction |
MGI:MGI:107405 |
P |
From MGI |
||
| GO:0009948 |
anterior/posterior axis specification |
MGI:MGI:3042338 |
IDA: Inferred from Direct Assay |
P |
From MGI |
|||
| GO:0009948 |
anterior/posterior axis specification |
MGI:MGI:3042338 |
IGI: Inferred from Genetic Interaction |
MGI:MGI:107405 |
P |
From MGI |
||
| GO:0009948 |
anterior/posterior axis specification |
MGI:MGI:3776330 |
IGI: Inferred from Genetic Interaction |
MGI:MGI:98658 |
P |
From MGI |
||
| GO:0009952 |
anterior/posterior pattern specification |
MGI:MGI:1197794 |
IDA: Inferred from Direct Assay |
P |
From MGI |
|||
| GO:0016015 |
morphogen activity |
MGI:MGI:4834177 |
ISO: Inferred from Sequence Orthology |
F |
From MGI |
|||
| GO:0023019 |
signal transduction involved in regulation of gene expression |
MGI:MGI:4415813 |
IDA: Inferred from Direct Assay |
P |
From MGI |
|||
| GO:0030282 |
bone mineralization |
MGI:MGI:4834177 |
ISO: Inferred from Sequence Orthology |
P |
From MGI |
|||
| GO:0030514 |
negative regulation of BMP signaling pathway |
MGI:MGI:1101446 |
IDA: Inferred from Direct Assay |
P |
From MGI |
|||
| GO:0030514 |
negative regulation of BMP signaling pathway |
MGI:MGI:1197794 |
IDA: Inferred from Direct Assay |
P |
From MGI |
|||
| GO:0032926 |
negative regulation of activin receptor signaling pathway |
MGI:MGI:1858315 |
IDA: Inferred from Direct Assay |
P |
From MGI |
|||
| GO:0032926 |
negative regulation of activin receptor signaling pathway |
MGI:MGI:4834177 |
ISO: Inferred from Sequence Orthology |
P |
From MGI |
|||
| GO:0035582 |
sequestering of BMP in extracellular matrix |
MGI:MGI:1858315 |
IDA: Inferred from Direct Assay |
P |
From MGI |
|||
| GO:0035582 |
sequestering of BMP in extracellular matrix |
MGI:MGI:4834177 |
ISO: Inferred from Sequence Orthology |
P |
From MGI |
|||
| GO:0036122 |
BMP binding |
MGI:MGI:4834177 |
ISO: Inferred from Sequence Orthology |
F |
From MGI |
|||
| GO:0042074 |
cell migration involved in gastrulation |
MGI:MGI:3042338 |
IGI: Inferred from Genetic Interaction |
MGI:MGI:107405 |
P |
From MGI |
||
| GO:0042803 |
protein homodimerization activity |
MGI:MGI:1858315 |
IDA: Inferred from Direct Assay |
F |
From MGI |
|||
| GO:0048263 |
determination of dorsal identity |
MGI:MGI:4834177 |
ISO: Inferred from Sequence Orthology |
P |
From MGI |
|||
| GO:0071773 |
cellular response to BMP stimulus |
MGI:MGI:5315345 |
ISS: Inferred from Sequence or Structural Similarity |
P |
From MGI |
|||
| GO:2000381 |
negative regulation of mesoderm development |
MGI:MGI:1858315 |
IDA: Inferred from Direct Assay |
P |
From MGI |
|||
| GO:2000381 |
negative regulation of mesoderm development |
MGI:MGI:4834177 |
ISO: Inferred from Sequence Orthology |
P |
From MGI |
|||
|
NOT |
GO:0030178 |
negative regulation of Wnt receptor signaling pathway |
MGI:MGI:1858315 |
IDA: Inferred from Direct Assay |
P |
From MGI |
| |
| edit table |
Notes
References
See Help:References for how to manage references in GONUTS.
- ↑ Chi L et al. (2011) A secreted BMP antagonist, Cer1, fine tunes the spatial organization of the ureteric bud tree during mouse kidney development. PLoS One 6: e27676 PubMed GONUTS page
- ↑ 2.0 2.1 Belo JA et al. (1997) Cerberus-like is a secreted factor with neutralizing activity expressed in the anterior primitive endoderm of the mouse gastrula. Mech Dev 68: 45-57 PubMed GONUTS page
- ↑ 3.0 3.1 3.2 3.3 3.4 3.5 Belo JA et al. (2000) Cerberus-like is a secreted BMP and nodal antagonist not essential for mouse development. Genesis 26: 265-70 PubMed GONUTS page
- ↑ 4.0 4.1 Liguori GL et al. (2008) Cripto-independent Nodal signaling promotes positioning of the A-P axis in the early mouse embryo. Dev Biol 315: 280-9 PubMed GONUTS page
- ↑ 5.0 5.1 5.2 5.3 Yamamoto M et al. (2004) Nodal antagonists regulate formation of the anteroposterior axis of the mouse embryo. Nature 428: 387-92 PubMed GONUTS page
- ↑ 6.0 6.1 Biben C et al. (1998) Murine cerberus homologue mCer-1: a candidate anterior patterning molecule. Dev Biol 194: 135-51 PubMed GONUTS page
- ↑ Lee D et al. (2008) ER71 acts downstream of BMP, Notch, and Wnt signaling in blood and vessel progenitor specification. Cell Stem Cell 2: 497-507 PubMed GONUTS page
- ↑ Simic P et al. (2006) Systemically administered bone morphogenetic protein-6 restores bone in aged ovariectomized rats by increasing bone formation and suppressing bone resorption. J Biol Chem 281: 25509-21 PubMed GONUTS page
