![]()
GONUTS is under stress! The website is currently experiencing long-wait times and frequent time-outs due to the record number of students, groups, and annotations related to CACAO this semester. We are currently working on increasing performance -- please accept our apologies for the technical difficulties.
You can help reduce stress on the server by:
- not reloading pages frequently - this just adds
- opening links in new windows (so you can read the old page)
MGI:Cebpg
Contents |
| Species (Taxon ID) | Mus musculus (house mouse) (taxon:10090) | |
| Gene Name(s) | Cebpg ( synonyms: C/EBPgamma, GPE1-BP, Gpe1bp, Ig/EBP ) | |
| Protein Name(s) | CCAAT/enhancer binding protein (C/EBP), gamma, | |
| External Links | ||
| MGI | MGI:104982 | |
Annotations
| Qualifier | GO ID | GO term name | Reference | Evidence Code | with/from | Aspect | Notes | Status |
|---|---|---|---|---|---|---|---|---|
| GO:0003677 |
DNA binding |
MGI:MGI:3687437 |
IDA: Inferred from Direct Assay |
F |
From MGI |
|||
| GO:0003677 |
DNA binding |
MGI:MGI:4417868 |
ISO: Inferred from Sequence Orthology |
F |
From MGI |
|||
| GO:0003677 |
DNA binding |
MGI:MGI:4834177 |
ISO: Inferred from Sequence Orthology |
F |
From MGI |
|||
| GO:0003690 |
double-stranded DNA binding |
MGI:MGI:4417868 |
ISO: Inferred from Sequence Orthology |
F |
From MGI |
|||
| GO:0005515 |
protein binding |
MGI:MGI:3693395 |
IPI: Inferred from Physical Interaction |
F |
From MGI |
|||
| GO:0005515 |
protein binding |
MGI:MGI:51489 |
IPI: Inferred from Physical Interaction |
F |
From MGI |
|||
| GO:0005634 |
nucleus |
MGI:MGI:4834177 |
ISO: Inferred from Sequence Orthology |
C |
From MGI |
|||
| GO:0005634 |
nucleus |
MGI:MGI:77483 |
IDA: Inferred from Direct Assay |
C |
From MGI |
|||
| GO:0006337 |
nucleosome disassembly |
MGI:MGI:3687428 |
TAS: Traceable Author Statement |
P |
From MGI |
|||
| GO:0006338 |
chromatin remodeling |
MGI:MGI:3687428 |
TAS: Traceable Author Statement |
P |
From MGI |
|||
| GO:0006351 |
transcription, DNA-dependent |
MGI:MGI:1354194 |
IEA: Inferred from Electronic Annotation |
UniProtKB-KW:KW-0804 |
P |
From MGI |
||
| GO:0006357 |
regulation of transcription from RNA polymerase II promoter |
MGI:MGI:3690192 |
ISO: Inferred from Sequence Orthology |
P |
From MGI |
|||
| GO:0006955 |
immune response |
MGI:MGI:1350450 |
IDA: Inferred from Direct Assay |
P |
From MGI |
|||
| GO:0008134 |
transcription factor binding |
MGI:MGI:4834177 |
ISO: Inferred from Sequence Orthology |
F |
From MGI |
|||
| GO:0008134 |
transcription factor binding |
MGI:MGI:77646 |
ISS: Inferred from Sequence or Structural Similarity |
F |
From MGI |
|||
| GO:0016071 |
mRNA metabolic process |
MGI:MGI:1202156 |
IMP: Inferred from Mutant Phenotype |
MGI:MGI:2177053 |
P |
From MGI |
||
| GO:0042267 |
natural killer cell mediated cytotoxicity |
MGI:MGI:1350450 |
IMP: Inferred from Mutant Phenotype |
P |
From MGI |
|||
| GO:0042803 |
protein homodimerization activity |
MGI:MGI:1927030 |
NAS: Non-traceable Author Statement |
F |
From MGI |
|||
| GO:0043353 |
enucleate erythrocyte differentiation |
MGI:MGI:1927030 |
IMP: Inferred from Mutant Phenotype |
P |
From MGI |
|||
| GO:0043433 |
negative regulation of sequence-specific DNA binding transcription factor activity |
MGI:MGI:77483 |
IDA: Inferred from Direct Assay |
P |
From MGI |
|||
| GO:0043565 |
sequence-specific DNA binding |
MGI:MGI:4834177 |
ISO: Inferred from Sequence Orthology |
F |
From MGI |
|||
| GO:0045078 |
positive regulation of interferon-gamma biosynthetic process |
MGI:MGI:1350450 |
IMP: Inferred from Mutant Phenotype |
P |
From MGI |
|||
| GO:0045739 |
positive regulation of DNA repair |
MGI:MGI:3690192 |
ISS: Inferred from Sequence or Structural Similarity |
P |
From MGI |
|||
| GO:0046982 |
protein heterodimerization activity |
MGI:MGI:4417868 |
ISO: Inferred from Sequence Orthology |
F |
From MGI |
|||
| GO:0046982 |
protein heterodimerization activity |
MGI:MGI:4834177 |
ISO: Inferred from Sequence Orthology |
F |
From MGI |
|||
| GO:0046983 |
protein dimerization activity |
MGI:MGI:2152098 |
IEA: Inferred from Electronic Annotation |
F |
From MGI |
|||
|
NOT |
GO:0003700 |
sequence-specific DNA binding transcription factor activity |
MGI:MGI:77483 |
IDA: Inferred from Direct Assay |
F |
From MGI |
||
|
NOT |
GO:0006355 |
regulation of transcription, DNA-dependent |
MGI:MGI:51489 |
IDA: Inferred from Direct Assay |
P |
From MGI |
| |
| edit table |
Notes
References
See Help:References for how to manage references in GONUTS.
- ↑ Cooper C et al. (1992) The C/EBP family of transcriptional activators is functionally important for Ig VH promoter activity in vivo and in vitro. J Immunol 149: 3225-31 PubMed GONUTS page
- ↑ Gao H et al. (2002) C/EBP gamma has a stimulatory role on the IL-6 and IL-8 promoters. J Biol Chem 277: 38827-37 PubMed GONUTS page
- ↑ 3.0 3.1 Nishizawa M & Nagata S (1992) cDNA clones encoding leucine-zipper proteins which interact with G-CSF gene promoter element 1-binding protein. FEBS Lett 299: 36-8 PubMed GONUTS page
- ↑ 4.0 4.1 4.2 Cooper C et al. (1995) Ig/EBP (C/EBP gamma) is a transdominant negative inhibitor of C/EBP family transcriptional activators. Nucleic Acids Res 23: 4371-7 PubMed GONUTS page
- ↑ 5.0 5.1 Cooper CL et al. (1994) Limited expression of C/EBP family proteins during B lymphocyte development. Negative regulator Ig/EBP predominates early and activator NF-IL-6 is induced later. J Immunol 153: 5049-58 PubMed GONUTS page
- ↑ 6.0 6.1 Mullins DN et al. (2005) CEBPG transcription factor correlates with antioxidant and DNA repair genes in normal bronchial epithelial cells but not in individuals with bronchogenic carcinoma. BMC Cancer 5: 141 PubMed GONUTS page
- ↑ 7.0 7.1 7.2 Kaisho T et al. (1999) Impairment of natural killer cytotoxic activity and interferon gamma production in CCAAT/enhancer binding protein gamma-deficient mice. J Exp Med 190: 1573-82 PubMed GONUTS page
- ↑ Davydov IV et al. (1995) Cloning of the cDNA encoding human C/EBP gamma, a protein binding to the PRE-I enhancer element of the human interleukin-4 promoter. Gene 161: 271-5 PubMed GONUTS page
- ↑ Oesterreicher TJ et al. (1998) Intestinal maturation in mice lacking CCAAT/enhancer-binding protein alpha (C/EPBalpha). Biochem J 330 ( Pt 3): 1165-71 PubMed GONUTS page
- ↑ 10.0 10.1 Zafarana G et al. (2000) Erythroid overexpression of C/EBPgamma in transgenic mice affects gamma-globin expression and fetal liver erythropoiesis. EMBO J 19: 5856-63 PubMed GONUTS page