Ambox notice.png

GONUTS is under stress! The website is currently experiencing long-wait times and frequent time-outs due to the record number of students, groups, and annotations related to CACAO this semester. We are currently working on increasing performance -- please accept our apologies for the technical difficulties.

You can help reduce stress on the server by:

  1. not reloading pages frequently - this just adds
  2. opening links in new windows (so you can read the old page)

MGI:Cebpg

From GONUTS
Jump to: navigation, search

Contents

Species (Taxon ID) Mus musculus (house mouse) (taxon:10090)
Gene Name(s) Cebpg ( synonyms: C/EBPgamma, GPE1-BP, Gpe1bp, Ig/EBP )
Protein Name(s) CCAAT/enhancer binding protein (C/EBP), gamma,
External Links
MGI MGI:104982

Annotations

Qualifier GO ID GO term name Reference Evidence Code with/from Aspect Notes Status
GO:0003677

DNA binding

MGI:MGI:3687437
PMID:1431100[1]

IDA: Inferred from Direct Assay

F

From MGI

GO:0003677

DNA binding

MGI:MGI:4417868

ISO: Inferred from Sequence Orthology

UniProtKB:P26801

F

From MGI

GO:0003677

DNA binding

MGI:MGI:4834177

ISO: Inferred from Sequence Orthology

UniProtKB:P53567

F

From MGI

GO:0003690

double-stranded DNA binding

MGI:MGI:4417868

ISO: Inferred from Sequence Orthology

UniProtKB:P26801

F

From MGI

GO:0005515

protein binding

MGI:MGI:3693395
PMID:12177065[2]

IPI: Inferred from Physical Interaction

UniProtKB:P28033
UniProtKB:Q00322

F

From MGI

GO:0005515

protein binding

MGI:MGI:51489
PMID:1371974[3]

IPI: Inferred from Physical Interaction

UniProtKB:Q06507

F

From MGI

GO:0005634

nucleus

MGI:MGI:4834177

ISO: Inferred from Sequence Orthology

UniProtKB:P53567

C

From MGI

GO:0005634

nucleus

MGI:MGI:77483
PMID:7501458[4]

IDA: Inferred from Direct Assay

C

From MGI

GO:0006337

nucleosome disassembly

MGI:MGI:3687428
PMID:7963564[5]

TAS: Traceable Author Statement

P

From MGI

GO:0006338

chromatin remodeling

MGI:MGI:3687428
PMID:7963564[5]

TAS: Traceable Author Statement

P

From MGI

GO:0006351

transcription, DNA-dependent

MGI:MGI:1354194

IEA: Inferred from Electronic Annotation

UniProtKB-KW:KW-0804

P

From MGI

GO:0006357

regulation of transcription from RNA polymerase II promoter

MGI:MGI:3690192
PMID:16255782[6]

ISO: Inferred from Sequence Orthology

UniProtKB:P53567

P

From MGI

GO:0006955

immune response

MGI:MGI:1350450
PMID:10587348[7]

IDA: Inferred from Direct Assay

P

From MGI

GO:0008134

transcription factor binding

MGI:MGI:4834177

ISO: Inferred from Sequence Orthology

UniProtKB:P53567

F

From MGI

GO:0008134

transcription factor binding

MGI:MGI:77646
PMID:7665092[8]

ISS: Inferred from Sequence or Structural Similarity

UniProtKB:P53567

F

From MGI

GO:0016071

mRNA metabolic process

MGI:MGI:1202156
PMID:9494081[9]

IMP: Inferred from Mutant Phenotype

MGI:MGI:2177053

P

From MGI

GO:0042267

natural killer cell mediated cytotoxicity

MGI:MGI:1350450
PMID:10587348[7]

IMP: Inferred from Mutant Phenotype

P

From MGI

GO:0042803

protein homodimerization activity

MGI:MGI:1927030
PMID:11060036[10]

NAS: Non-traceable Author Statement

F

From MGI

GO:0043353

enucleate erythrocyte differentiation

MGI:MGI:1927030
PMID:11060036[10]

IMP: Inferred from Mutant Phenotype

P

From MGI

GO:0043433

negative regulation of sequence-specific DNA binding transcription factor activity

MGI:MGI:77483
PMID:7501458[4]

IDA: Inferred from Direct Assay

P

From MGI

GO:0043565

sequence-specific DNA binding

MGI:MGI:4834177

ISO: Inferred from Sequence Orthology

UniProtKB:P53567

F

From MGI

GO:0045078

positive regulation of interferon-gamma biosynthetic process

MGI:MGI:1350450
PMID:10587348[7]

IMP: Inferred from Mutant Phenotype

P

From MGI

GO:0045739

positive regulation of DNA repair

MGI:MGI:3690192
PMID:16255782[6]

ISS: Inferred from Sequence or Structural Similarity

UniProtKB:P53567

P

From MGI

GO:0046982

protein heterodimerization activity

MGI:MGI:4417868

ISO: Inferred from Sequence Orthology

UniProtKB:P26801

F

From MGI

GO:0046982

protein heterodimerization activity

MGI:MGI:4834177

ISO: Inferred from Sequence Orthology

UniProtKB:P53567

F

From MGI

GO:0046983

protein dimerization activity

MGI:MGI:2152098

IEA: Inferred from Electronic Annotation

InterPro:IPR011700

F

From MGI

NOT

GO:0003700

sequence-specific DNA binding transcription factor activity

MGI:MGI:77483
PMID:7501458[4]

IDA: Inferred from Direct Assay

F

From MGI

NOT

GO:0006355

regulation of transcription, DNA-dependent

MGI:MGI:51489
PMID:1371974[3]

IDA: Inferred from Direct Assay

P

From MGI


Notes

References

See Help:References for how to manage references in GONUTS.
  1. Cooper C et al. (1992) The C/EBP family of transcriptional activators is functionally important for Ig VH promoter activity in vivo and in vitro. J Immunol 149: 3225-31 PubMed GONUTS page
  2. Gao H et al. (2002) C/EBP gamma has a stimulatory role on the IL-6 and IL-8 promoters. J Biol Chem 277: 38827-37 PubMed GONUTS page
  3. 3.0 3.1 Nishizawa M & Nagata S (1992) cDNA clones encoding leucine-zipper proteins which interact with G-CSF gene promoter element 1-binding protein. FEBS Lett 299: 36-8 PubMed GONUTS page
  4. 4.0 4.1 4.2 Cooper C et al. (1995) Ig/EBP (C/EBP gamma) is a transdominant negative inhibitor of C/EBP family transcriptional activators. Nucleic Acids Res 23: 4371-7 PubMed GONUTS page
  5. 5.0 5.1 Cooper CL et al. (1994) Limited expression of C/EBP family proteins during B lymphocyte development. Negative regulator Ig/EBP predominates early and activator NF-IL-6 is induced later. J Immunol 153: 5049-58 PubMed GONUTS page
  6. 6.0 6.1 Mullins DN et al. (2005) CEBPG transcription factor correlates with antioxidant and DNA repair genes in normal bronchial epithelial cells but not in individuals with bronchogenic carcinoma. BMC Cancer 5: 141 PubMed GONUTS page
  7. 7.0 7.1 7.2 Kaisho T et al. (1999) Impairment of natural killer cytotoxic activity and interferon gamma production in CCAAT/enhancer binding protein gamma-deficient mice. J Exp Med 190: 1573-82 PubMed GONUTS page
  8. Davydov IV et al. (1995) Cloning of the cDNA encoding human C/EBP gamma, a protein binding to the PRE-I enhancer element of the human interleukin-4 promoter. Gene 161: 271-5 PubMed GONUTS page
  9. Oesterreicher TJ et al. (1998) Intestinal maturation in mice lacking CCAAT/enhancer-binding protein alpha (C/EPBalpha). Biochem J 330 ( Pt 3): 1165-71 PubMed GONUTS page
  10. 10.0 10.1 Zafarana G et al. (2000) Erythroid overexpression of C/EBPgamma in transgenic mice affects gamma-globin expression and fetal liver erythropoiesis. EMBO J 19: 5856-63 PubMed GONUTS page
Personal tools
Namespaces
Variants
Actions
Navigation
Cacao
Journal Clubs
page contributors
Toolbox