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MGI:Cdk9

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Contents

Species (Taxon ID) Mus musculus (house mouse) (taxon:10090)
Gene Name(s) Cdk9 ( synonyms: PITALRE )
Protein Name(s) cyclin-dependent kinase 9 (CDC2-related kinase),
External Links
MGI MGI:1328368

Annotations

Qualifier GO ID GO term name Reference Evidence Code with/from Aspect Notes Status
GO:0000166

nucleotide binding

MGI:MGI:1354194

IEA: Inferred from Electronic Annotation

UniProtKB-KW:KW-0547

F

From MGI

GO:0003677

DNA binding

MGI:MGI:3590381
PMID:16109376[1]

ISO: Inferred from Sequence Orthology

UniProtKB:P50750

F

From MGI

GO:0004672

protein kinase activity

MGI:MGI:2152098

IEA: Inferred from Electronic Annotation

InterPro:IPR000719
InterPro:IPR002290

F

From MGI

GO:0004674

protein serine/threonine kinase activity

MGI:MGI:1354194

IEA: Inferred from Electronic Annotation

UniProtKB-KW:KW-0723

F

From MGI

GO:0004674

protein serine/threonine kinase activity

MGI:MGI:2152098

IEA: Inferred from Electronic Annotation

InterPro:IPR008271

F

From MGI

GO:0004693

cyclin-dependent protein kinase activity

MGI:MGI:2152096

IEA: Inferred from Electronic Annotation

EC:2.7.11.22

F

From MGI

GO:0005515

protein binding

MGI:MGI:4839428
PMID:20434984[2]

IPI: Inferred from Physical Interaction

UniProtKB:P28574

F

From MGI

GO:0005524

ATP binding

MGI:MGI:1354194

IEA: Inferred from Electronic Annotation

UniProtKB-KW:KW-0067

F

From MGI

GO:0005524

ATP binding

MGI:MGI:2152098

IEA: Inferred from Electronic Annotation

InterPro:IPR000719
InterPro:IPR017441
InterPro:IPR002290

F

From MGI

GO:0005634

nucleus

MGI:MGI:3590381
PMID:16109376[1]

IDA: Inferred from Direct Assay

C

From MGI

GO:0005634

nucleus

MGI:MGI:4834177

ISO: Inferred from Sequence Orthology

UniProtKB:P50750

C

From MGI

GO:0005737

cytoplasm

MGI:MGI:1354194

IEA: Inferred from Electronic Annotation

UniProtKB-KW:KW-0963

C

From MGI

GO:0006281

DNA repair

MGI:MGI:1354194

IEA: Inferred from Electronic Annotation

UniProtKB-KW:KW-0234

P

From MGI

GO:0006282

regulation of DNA repair

MGI:MGI:4834177

ISO: Inferred from Sequence Orthology

UniProtKB:P50750

P

From MGI

GO:0006351

transcription, DNA-dependent

MGI:MGI:1354194

IEA: Inferred from Electronic Annotation

UniProtKB-KW:KW-0804

P

From MGI

GO:0006355

regulation of transcription, DNA-dependent

MGI:MGI:1354194

IEA: Inferred from Electronic Annotation

UniProtKB-KW:KW-0805

P

From MGI

GO:0006468

protein phosphorylation

MGI:MGI:3590381
PMID:16109376[1]

ISO: Inferred from Sequence Orthology

UniProtKB:P50750

P

From MGI

GO:0006974

response to DNA damage stimulus

MGI:MGI:1354194

IEA: Inferred from Electronic Annotation

UniProtKB-KW:KW-0227

P

From MGI

GO:0007049

cell cycle

MGI:MGI:2152096

IEA: Inferred from Electronic Annotation

EC:2.7.11.22

P

From MGI

GO:0008024

positive transcription elongation factor complex b

MGI:MGI:4834059
PMID:20570862[3]

TAS: Traceable Author Statement

C

From MGI

GO:0008353

RNA polymerase II carboxy-terminal domain kinase activity

MGI:MGI:4834177

ISO: Inferred from Sequence Orthology

UniProtKB:P50750

F

From MGI

GO:0016301

kinase activity

MGI:MGI:1354194

IEA: Inferred from Electronic Annotation

UniProtKB-KW:KW-0418

F

From MGI

GO:0016310

phosphorylation

MGI:MGI:1354194

IEA: Inferred from Electronic Annotation

UniProtKB-KW:KW-0418

P

From MGI

GO:0016605

PML body

MGI:MGI:4834177

ISO: Inferred from Sequence Orthology

UniProtKB:P50750

C

From MGI

GO:0016740

transferase activity

MGI:MGI:1354194

IEA: Inferred from Electronic Annotation

UniProtKB-KW:KW-0808

F

From MGI

GO:0016772

transferase activity, transferring phosphorus-containing groups

MGI:MGI:2152098

IEA: Inferred from Electronic Annotation

InterPro:IPR011009

F

From MGI

GO:0017069

snRNA binding

MGI:MGI:3590381
PMID:16109376[1]

IDA: Inferred from Direct Assay

F

From MGI

GO:0031056

regulation of histone modification

MGI:MGI:4834177

ISO: Inferred from Sequence Orthology

UniProtKB:P50750

P

From MGI

GO:0043111

replication fork arrest

MGI:MGI:4834177

ISO: Inferred from Sequence Orthology

UniProtKB:P50750

P

From MGI

GO:0043231

intracellular membrane-bounded organelle

MGI:MGI:4834177

ISO: Inferred from Sequence Orthology

UniProtKB:P50750

C

From MGI

GO:0044212

transcription regulatory region DNA binding

MGI:MGI:4834059
PMID:20570862[3]

IDA: Inferred from Direct Assay

F

From MGI

GO:0071157

negative regulation of cell cycle arrest

MGI:MGI:4834177

ISO: Inferred from Sequence Orthology

UniProtKB:P50750

P

From MGI

GO:0071345

cellular response to cytokine stimulus

MGI:MGI:4834177

ISO: Inferred from Sequence Orthology

UniProtKB:P50750

P

From MGI


Notes

References

See Help:References for how to manage references in GONUTS.
  1. 1.0 1.1 1.2 1.3 Jang MK et al. (2005) The bromodomain protein Brd4 is a positive regulatory component of P-TEFb and stimulates RNA polymerase II-dependent transcription. Mol Cell 19: 523-34 PubMed GONUTS page
  2. Rahl PB et al. (2010) c-Myc regulates transcriptional pause release. Cell 141: 432-45 PubMed GONUTS page
  3. 3.0 3.1 Song SH et al. (2010) Multiple functions of Ldb1 required for beta-globin activation during erythroid differentiation. Blood 116: 2356-64 PubMed GONUTS page
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