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MGI:Cdk5rap2
Contents |
| Species (Taxon ID) | Mus musculus (house mouse) (taxon:10090) | |
| Gene Name(s) | Cdk5rap2 ( synonyms: an ) | |
| Protein Name(s) | CDK5 regulatory subunit associated protein 2, | |
| External Links | ||
| MGI | MGI:2384875 | |
Annotations
| Qualifier | GO ID | GO term name | Reference | Evidence Code | with/from | Aspect | Notes | Status |
|---|---|---|---|---|---|---|---|---|
| GO:0000132 |
establishment of mitotic spindle orientation |
MGI:MGI:4454588 |
IMP: Inferred from Mutant Phenotype |
P |
From MGI |
|||
| GO:0000226 |
microtubule cytoskeleton organization |
MGI:MGI:4834177 |
ISO: Inferred from Sequence Orthology |
P |
From MGI |
|||
| GO:0000242 |
pericentriolar material |
MGI:MGI:4834177 |
ISO: Inferred from Sequence Orthology |
C |
From MGI |
|||
| GO:0000922 |
spindle pole |
MGI:MGI:4834177 |
ISO: Inferred from Sequence Orthology |
C |
From MGI |
|||
| GO:0001578 |
microtubule bundle formation |
MGI:MGI:4834177 |
ISO: Inferred from Sequence Orthology |
P |
From MGI |
|||
| GO:0005515 |
protein binding |
MGI:MGI:4454949 |
IPI: Inferred from Physical Interaction |
F |
From MGI |
|||
| GO:0005516 |
calmodulin binding |
MGI:MGI:4834177 |
ISO: Inferred from Sequence Orthology |
F |
From MGI |
|||
| GO:0005623 |
cell |
MGI:MGI:4454588 |
IMP: Inferred from Mutant Phenotype |
C |
From MGI |
|||
| GO:0005737 |
cytoplasm |
MGI:MGI:4834177 |
ISO: Inferred from Sequence Orthology |
C |
From MGI |
|||
| GO:0005794 |
Golgi apparatus |
MGI:MGI:4834177 |
ISO: Inferred from Sequence Orthology |
C |
From MGI |
|||
| GO:0005813 |
centrosome |
MGI:MGI:3762422 |
IDA: Inferred from Direct Assay |
C |
From MGI |
|||
| GO:0005813 |
centrosome |
MGI:MGI:4454949 |
IDA: Inferred from Direct Assay |
C |
From MGI |
|||
| GO:0005813 |
centrosome |
MGI:MGI:4830038 |
IDA: Inferred from Direct Assay |
C |
From MGI |
|||
| GO:0005813 |
centrosome |
MGI:MGI:4834177 |
ISO: Inferred from Sequence Orthology |
C |
From MGI |
|||
| GO:0005856 |
cytoskeleton |
MGI:MGI:1354194 |
IEA: Inferred from Electronic Annotation |
UniProtKB-KW:KW-0206 |
C |
From MGI |
||
| GO:0005874 |
microtubule |
MGI:MGI:4834177 |
ISO: Inferred from Sequence Orthology |
C |
From MGI |
|||
| GO:0007059 |
chromosome segregation |
MGI:MGI:4834177 |
ISO: Inferred from Sequence Orthology |
P |
From MGI |
|||
| GO:0007420 |
brain development |
MGI:MGI:4454588 |
IMP: Inferred from Mutant Phenotype |
P |
From MGI |
|||
| GO:0008017 |
microtubule binding |
MGI:MGI:4834177 |
ISO: Inferred from Sequence Orthology |
F |
From MGI |
|||
| GO:0015631 |
tubulin binding |
MGI:MGI:4834177 |
ISO: Inferred from Sequence Orthology |
F |
From MGI |
|||
| GO:0022008 |
neurogenesis |
MGI:MGI:4454588 |
IMP: Inferred from Mutant Phenotype |
P |
From MGI |
|||
| GO:0030054 |
cell junction |
MGI:MGI:4834177 |
ISO: Inferred from Sequence Orthology |
C |
From MGI |
|||
| GO:0032403 |
protein complex binding |
MGI:MGI:4417868 |
ISO: Inferred from Sequence Orthology |
NCBI:NP_775157 |
F |
From MGI |
||
| GO:0044212 |
transcription regulatory region DNA binding |
MGI:MGI:4834177 |
ISO: Inferred from Sequence Orthology |
F |
From MGI |
|||
| GO:0045665 |
negative regulation of neuron differentiation |
MGI:MGI:4454949 |
IMP: Inferred from Mutant Phenotype |
P |
From MGI |
|||
| GO:0045893 |
positive regulation of transcription, DNA-dependent |
MGI:MGI:4834177 |
ISO: Inferred from Sequence Orthology |
P |
From MGI |
|||
| GO:0046600 |
negative regulation of centriole replication |
MGI:MGI:4830038 |
IMP: Inferred from Mutant Phenotype |
P |
From MGI |
|||
| GO:0048471 |
perinuclear region of cytoplasm |
MGI:MGI:4834177 |
ISO: Inferred from Sequence Orthology |
C |
From MGI |
|||
| GO:0051297 |
centrosome organization |
MGI:MGI:4834177 |
ISO: Inferred from Sequence Orthology |
P |
From MGI |
|||
| GO:0090231 |
regulation of spindle checkpoint |
MGI:MGI:4834177 |
ISO: Inferred from Sequence Orthology |
P |
From MGI |
| ||
| edit table |
Notes
References
See Help:References for how to manage references in GONUTS.
- ↑ 1.0 1.1 1.2 1.3 Lizarraga SB et al. (2010) Cdk5rap2 regulates centrosome function and chromosome segregation in neuronal progenitors. Development 137: 1907-17 PubMed GONUTS page
- ↑ 2.0 2.1 2.2 Buchman JJ et al. (2010) Cdk5rap2 interacts with pericentrin to maintain the neural progenitor pool in the developing neocortex. Neuron 66: 386-402 PubMed GONUTS page
- ↑ Xie Z et al. (2007) Cep120 and TACCs control interkinetic nuclear migration and the neural progenitor pool. Neuron 56: 79-93 PubMed GONUTS page
- ↑ 4.0 4.1 Barrera JA et al. (2010) CDK5RAP2 regulates centriole engagement and cohesion in mice. Dev Cell 18: 913-26 PubMed GONUTS page
