![]()
GONUTS is under stress! The website is currently experiencing long-wait times and frequent time-outs due to the record number of students, groups, and annotations related to CACAO this semester. We are currently working on increasing performance -- please accept our apologies for the technical difficulties.
You can help reduce stress on the server by:
- not reloading pages frequently - this just adds
- opening links in new windows (so you can read the old page)
MGI:Cdk5r2
Contents |
| Species (Taxon ID) | Mus musculus (house mouse) (taxon:10090) | |
| Gene Name(s) | Cdk5r2 ( synonyms: p39 ) | |
| Protein Name(s) | cyclin-dependent kinase 5, regulatory subunit 2 (p39), | |
| External Links | ||
| MGI | MGI:1330828 | |
Annotations
| Qualifier | GO ID | GO term name | Reference | Evidence Code | with/from | Aspect | Notes | Status |
|---|---|---|---|---|---|---|---|---|
| GO:0001764 |
neuron migration |
MGI:MGI:2149271 |
IGI: Inferred from Genetic Interaction |
MGI:MGI:101764 |
P |
From MGI |
||
| GO:0001934 |
positive regulation of protein phosphorylation |
MGI:MGI:2149271 |
IMP: Inferred from Mutant Phenotype |
MGI:MGI:2387662 |
P |
From MGI |
||
| GO:0001934 |
positive regulation of protein phosphorylation |
MGI:MGI:2447288 |
TAS: Traceable Author Statement |
P |
From MGI |
|||
| GO:0005737 |
cytoplasm |
MGI:MGI:3709145 |
IDA: Inferred from Direct Assay |
C |
From MGI |
|||
| GO:0005886 |
plasma membrane |
MGI:MGI:1354194 |
IEA: Inferred from Electronic Annotation |
UniProtKB-KW:KW-1003 |
C |
From MGI |
||
| GO:0008092 |
cytoskeletal protein binding |
MGI:MGI:2446382 |
TAS: Traceable Author Statement |
F |
From MGI |
|||
| GO:0008289 |
lipid binding |
MGI:MGI:1354194 |
IEA: Inferred from Electronic Annotation |
UniProtKB-KW:KW-0446 |
F |
From MGI |
||
| GO:0016020 |
membrane |
MGI:MGI:1354194 |
IEA: Inferred from Electronic Annotation |
UniProtKB-KW:KW-0472 |
C |
From MGI |
||
| GO:0016533 |
cyclin-dependent protein kinase 5 holoenzyme complex |
MGI:MGI:2152098 |
IEA: Inferred from Electronic Annotation |
C |
From MGI |
|||
| GO:0016534 |
cyclin-dependent protein kinase 5 activator activity |
MGI:MGI:2149271 |
IMP: Inferred from Mutant Phenotype |
MGI:MGI:2387662 |
F |
From MGI |
||
| GO:0016534 |
cyclin-dependent protein kinase 5 activator activity |
MGI:MGI:2447288 |
TAS: Traceable Author Statement |
F |
From MGI |
|||
| GO:0021549 |
cerebellum development |
MGI:MGI:2149271 |
IGI: Inferred from Genetic Interaction |
MGI:MGI:101764 |
P |
From MGI |
||
| GO:0021722 |
superior olivary nucleus maturation |
MGI:MGI:2149271 |
IGI: Inferred from Genetic Interaction |
MGI:MGI:101764 |
P |
From MGI |
||
| GO:0021766 |
hippocampus development |
MGI:MGI:2149271 |
IGI: Inferred from Genetic Interaction |
MGI:MGI:101764 |
P |
From MGI |
||
| GO:0021819 |
layer formation in cerebral cortex |
MGI:MGI:2149271 |
IGI: Inferred from Genetic Interaction |
MGI:MGI:101764 |
P |
From MGI |
||
| GO:0045860 |
positive regulation of protein kinase activity |
MGI:MGI:2149271 |
IGI: Inferred from Genetic Interaction |
MGI:MGI:101764 |
P |
From MGI |
||
| GO:0045956 |
positive regulation of calcium ion-dependent exocytosis |
MGI:MGI:3709145 |
IDA: Inferred from Direct Assay |
P |
From MGI |
|||
| GO:0071902 |
positive regulation of protein serine/threonine kinase activity |
MGI:MGI:2149271 |
IMP: Inferred from Mutant Phenotype |
MGI:MGI:2387662 |
P |
From MGI |
| |
| edit table |
Notes
References
See Help:References for how to manage references in GONUTS.
- ↑ 1.0 1.1 1.2 1.3 1.4 1.5 1.6 1.7 1.8 Ko J et al. (2001) p35 and p39 are essential for cyclin-dependent kinase 5 function during neurodevelopment. J Neurosci 21: 6758-71 PubMed GONUTS page
- ↑ 2.0 2.1 Wilson ME et al. (2002) The TGF-beta response to Leishmania chagasi in the absence of IL-12. Eur J Immunol 32: 3556-65 PubMed GONUTS page
- ↑ 3.0 3.1 Lilja L et al. (2004) Cyclin-dependent kinase 5 associated with p39 promotes Munc18-1 phosphorylation and Ca(2+)-dependent exocytosis. J Biol Chem 279: 29534-41 PubMed GONUTS page
- ↑ Gao C et al. (2002) CDK5 regulates cell adhesion and migration in corneal epithelial cells. Mol Cancer Res 1: 12-24 PubMed GONUTS page