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MGI:Cdk5r2

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Contents

Species (Taxon ID) Mus musculus (house mouse) (taxon:10090)
Gene Name(s) Cdk5r2 ( synonyms: p39 )
Protein Name(s) cyclin-dependent kinase 5, regulatory subunit 2 (p39),
External Links
MGI MGI:1330828

Annotations

Qualifier GO ID GO term name Reference Evidence Code with/from Aspect Notes Status
GO:0001764

neuron migration

MGI:MGI:2149271
PMID:11517264[1]

IGI: Inferred from Genetic Interaction

MGI:MGI:101764

P

From MGI

GO:0001934

positive regulation of protein phosphorylation

MGI:MGI:2149271
PMID:11517264[1]

IMP: Inferred from Mutant Phenotype

MGI:MGI:2387662

P

From MGI

GO:0001934

positive regulation of protein phosphorylation

MGI:MGI:2447288
PMID:12516540[2]

TAS: Traceable Author Statement

P

From MGI

GO:0005737

cytoplasm

MGI:MGI:3709145
PMID:15123626[3]

IDA: Inferred from Direct Assay

C

From MGI

GO:0005886

plasma membrane

MGI:MGI:1354194

IEA: Inferred from Electronic Annotation

UniProtKB-KW:KW-1003

C

From MGI

GO:0008092

cytoskeletal protein binding

MGI:MGI:2446382
PMID:12496365[4]

TAS: Traceable Author Statement

F

From MGI

GO:0008289

lipid binding

MGI:MGI:1354194

IEA: Inferred from Electronic Annotation

UniProtKB-KW:KW-0446

F

From MGI

GO:0016020

membrane

MGI:MGI:1354194

IEA: Inferred from Electronic Annotation

UniProtKB-KW:KW-0472

C

From MGI

GO:0016533

cyclin-dependent protein kinase 5 holoenzyme complex

MGI:MGI:2152098

IEA: Inferred from Electronic Annotation

InterPro:IPR004944

C

From MGI

GO:0016534

cyclin-dependent protein kinase 5 activator activity

MGI:MGI:2149271
PMID:11517264[1]

IMP: Inferred from Mutant Phenotype

MGI:MGI:2387662

F

From MGI

GO:0016534

cyclin-dependent protein kinase 5 activator activity

MGI:MGI:2447288
PMID:12516540[2]

TAS: Traceable Author Statement

F

From MGI

GO:0021549

cerebellum development

MGI:MGI:2149271
PMID:11517264[1]

IGI: Inferred from Genetic Interaction

MGI:MGI:101764

P

From MGI

GO:0021722

superior olivary nucleus maturation

MGI:MGI:2149271
PMID:11517264[1]

IGI: Inferred from Genetic Interaction

MGI:MGI:101764

P

From MGI

GO:0021766

hippocampus development

MGI:MGI:2149271
PMID:11517264[1]

IGI: Inferred from Genetic Interaction

MGI:MGI:101764

P

From MGI

GO:0021819

layer formation in cerebral cortex

MGI:MGI:2149271
PMID:11517264[1]

IGI: Inferred from Genetic Interaction

MGI:MGI:101764

P

From MGI

GO:0045860

positive regulation of protein kinase activity

MGI:MGI:2149271
PMID:11517264[1]

IGI: Inferred from Genetic Interaction

MGI:MGI:101764

P

From MGI

GO:0045956

positive regulation of calcium ion-dependent exocytosis

MGI:MGI:3709145
PMID:15123626[3]

IDA: Inferred from Direct Assay

P

From MGI

GO:0071902

positive regulation of protein serine/threonine kinase activity

MGI:MGI:2149271
PMID:11517264[1]

IMP: Inferred from Mutant Phenotype

MGI:MGI:2387662

P

From MGI


Notes

References

See Help:References for how to manage references in GONUTS.
  1. 1.0 1.1 1.2 1.3 1.4 1.5 1.6 1.7 1.8 Ko J et al. (2001) p35 and p39 are essential for cyclin-dependent kinase 5 function during neurodevelopment. J Neurosci 21: 6758-71 PubMed GONUTS page
  2. 2.0 2.1 Wilson ME et al. (2002) The TGF-beta response to Leishmania chagasi in the absence of IL-12. Eur J Immunol 32: 3556-65 PubMed GONUTS page
  3. 3.0 3.1 Lilja L et al. (2004) Cyclin-dependent kinase 5 associated with p39 promotes Munc18-1 phosphorylation and Ca(2+)-dependent exocytosis. J Biol Chem 279: 29534-41 PubMed GONUTS page
  4. Gao C et al. (2002) CDK5 regulates cell adhesion and migration in corneal epithelial cells. Mol Cancer Res 1: 12-24 PubMed GONUTS page
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