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MGI:Cdh5
Contents |
| Species (Taxon ID) | Mus musculus (house mouse) (taxon:10090) | |
| Gene Name(s) | Cdh5 ( synonyms: 7B4/cadherin-5, CD144, VE-Cad, VE-cadherin, VEC, VEcad, VECD ) | |
| Protein Name(s) | cadherin 5, | |
| External Links | ||
| MGI | MGI:105057 | |
Annotations
| Qualifier | GO ID | GO term name | Reference | Evidence Code | with/from | Aspect | Notes | Status |
|---|---|---|---|---|---|---|---|---|
| GO:0001955 |
blood vessel maturation |
MGI:MGI:3578504 |
IMP: Inferred from Mutant Phenotype |
MGI:MGI:1857669 |
P |
From MGI |
||
| GO:0005102 |
receptor binding |
MGI:MGI:4834177 |
ISO: Inferred from Sequence Orthology |
F |
From MGI |
|||
| GO:0005509 |
calcium ion binding |
MGI:MGI:2152098 |
IEA: Inferred from Electronic Annotation |
F |
From MGI |
|||
| GO:0005515 |
protein binding |
MGI:MGI:3577866 |
IPI: Inferred from Physical Interaction |
F |
From MGI |
|||
| GO:0005515 |
protein binding |
MGI:MGI:4419091 |
IPI: Inferred from Physical Interaction |
F |
From MGI |
|||
| GO:0005886 |
plasma membrane |
MGI:MGI:1354194 |
IEA: Inferred from Electronic Annotation |
UniProtKB-KW:KW-1003 |
C |
From MGI |
||
| GO:0005886 |
plasma membrane |
MGI:MGI:2152098 |
IEA: Inferred from Electronic Annotation |
C |
From MGI |
|||
| GO:0005911 |
cell-cell junction |
MGI:MGI:3577866 |
IDA: Inferred from Direct Assay |
C |
From MGI |
|||
| GO:0005911 |
cell-cell junction |
MGI:MGI:3837878 |
ISO: Inferred from Sequence Orthology |
C |
From MGI |
|||
| GO:0005911 |
cell-cell junction |
MGI:MGI:4834177 |
ISO: Inferred from Sequence Orthology |
C |
From MGI |
|||
| GO:0005911 |
cell-cell junction |
MGI:MGI:5295345 |
IDA: Inferred from Direct Assay |
C |
From MGI |
|||
| GO:0005923 |
tight junction |
MGI:MGI:3513971 |
IDA: Inferred from Direct Assay |
C |
From MGI |
|||
| GO:0007155 |
cell adhesion |
MGI:MGI:1354194 |
IEA: Inferred from Electronic Annotation |
UniProtKB-KW:KW-0130 |
P |
From MGI |
||
| GO:0007155 |
cell adhesion |
MGI:MGI:2152098 |
IEA: Inferred from Electronic Annotation |
P |
From MGI |
|||
| GO:0007156 |
homophilic cell adhesion |
MGI:MGI:2152098 |
IEA: Inferred from Electronic Annotation |
P |
From MGI |
|||
| GO:0008013 |
beta-catenin binding |
MGI:MGI:4834177 |
ISO: Inferred from Sequence Orthology |
F |
From MGI |
|||
| GO:0008285 |
negative regulation of cell proliferation |
MGI:MGI:3577866 |
IGI: Inferred from Genetic Interaction |
MGI:MGI:88537 |
P |
From MGI |
||
| GO:0016020 |
membrane |
MGI:MGI:1354194 |
IEA: Inferred from Electronic Annotation |
UniProtKB-KW:KW-0472 |
C |
From MGI |
||
| GO:0016020 |
membrane |
MGI:MGI:2152098 |
IEA: Inferred from Electronic Annotation |
C |
From MGI |
|||
| GO:0016021 |
integral to membrane |
MGI:MGI:1354194 |
IEA: Inferred from Electronic Annotation |
UniProtKB-KW:KW-0812 |
C |
From MGI |
||
| GO:0016337 |
cell-cell adhesion |
MGI:MGI:3513971 |
IC: Inferred by Curator |
GO:0005923 |
P |
From MGI |
||
| GO:0016337 |
cell-cell adhesion |
MGI:MGI:5295345 |
IMP: Inferred from Mutant Phenotype |
P |
From MGI |
|||
| GO:0019903 |
protein phosphatase binding |
MGI:MGI:3689290 |
IPI: Inferred from Physical Interaction |
F |
From MGI |
|||
| GO:0030054 |
cell junction |
MGI:MGI:1354194 |
IEA: Inferred from Electronic Annotation |
UniProtKB-KW:KW-0965 |
C |
From MGI |
||
| GO:0042153 |
RPTP-like protein binding |
MGI:MGI:3689290 |
IPI: Inferred from Physical Interaction |
F |
From MGI |
|||
| GO:0044325 |
ion channel binding |
MGI:MGI:4834177 |
ISO: Inferred from Sequence Orthology |
F |
From MGI |
|||
| GO:2000114 |
regulation of establishment of cell polarity |
MGI:MGI:4834177 |
ISO: Inferred from Sequence Orthology |
P |
From MGI |
|||
| GO:2000114 |
regulation of establishment of cell polarity |
MGI:MGI:4943837 |
IMP: Inferred from Mutant Phenotype |
P |
From MGI |
| ||
| edit table |
Notes
References
See Help:References for how to manage references in GONUTS.
- ↑ Howell DC et al. (2005) Absence of proteinase-activated receptor-1 signaling affords protection from bleomycin-induced lung inflammation and fibrosis. Am J Pathol 166: 1353-65 PubMed GONUTS page
- ↑ 2.0 2.1 2.2 Baumeister U et al. (2005) Association of Csk to VE-cadherin and inhibition of cell proliferation. EMBO J 24: 1686-95 PubMed GONUTS page
- ↑ Nawroth R et al. (2002) VE-PTP and VE-cadherin ectodomains interact to facilitate regulation of phosphorylation and cell contacts. EMBO J 21: 4885-95 PubMed GONUTS page
- ↑ Kleaveland B et al. (2009) Regulation of cardiovascular development and integrity by the heart of glass-cerebral cavernous malformation protein pathway. Nat Med 15: 169-76 PubMed GONUTS page
- ↑ 5.0 5.1 Akashi M et al. (2011) A coronary artery disease-associated gene product, JCAD/KIAA1462, is a novel component of endothelial cell-cell junctions. Biochem Biophys Res Commun 413: 224-9 PubMed GONUTS page
- ↑ 6.0 6.1 Morita K et al. (1999) Endothelial claudin: claudin-5/TMVCF constitutes tight junction strands in endothelial cells. J Cell Biol 147: 185-94 PubMed GONUTS page
- ↑ 7.0 7.1 Besco JA et al. (2006) Intracellular substrates of brain-enriched receptor protein tyrosine phosphatase rho (RPTPrho/PTPRT). Brain Res 1116: 50-7 PubMed GONUTS page
- ↑ Lampugnani MG et al. (2010) CCM1 regulates vascular-lumen organization by inducing endothelial polarity. J Cell Sci 123: 1073-80 PubMed GONUTS page
