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MGI:Cdc2a
Contents |
| Species (Taxon ID) | Mus musculus (house mouse) (taxon:10090) | |
| Gene Name(s) | Cdc2a ( synonyms: Cdc2, CDK1, p34 ) | |
| Protein Name(s) | cell division cycle 2 homolog A (S. pombe), | |
| External Links | ||
| MGI | MGI:88351 | |
Annotations
| Qualifier | GO ID | GO term name | Reference(s) | Evidence Code | with/from | Aspect | Notes | Status |
|---|---|---|---|---|---|---|---|---|
| GO:0000166 |
nucleotide binding |
MGI:MGI:1354194 |
IEA: Inferred from Electronic Annotation |
F |
From MGI |
|||
| GO:0004672 |
protein kinase activity |
MGI:MGI:2152098 |
IEA: Inferred from Electronic Annotation |
F |
From MGI |
|||
| GO:0004674 |
protein serine/threonine kinase activity |
MGI:MGI:1354194 |
IEA: Inferred from Electronic Annotation |
F |
From MGI |
|||
| GO:0004674 |
protein serine/threonine kinase activity |
MGI:MGI:2152098 |
IEA: Inferred from Electronic Annotation |
F |
From MGI |
|||
| GO:0004693 |
cyclin-dependent protein kinase activity |
MGI:MGI:2152096 |
IEA: Inferred from Electronic Annotation |
F |
From MGI |
|||
| GO:0005524 |
ATP binding |
MGI:MGI:1354194 |
IEA: Inferred from Electronic Annotation |
F |
From MGI |
|||
| GO:0005524 |
ATP binding |
MGI:MGI:2152098 |
IEA: Inferred from Electronic Annotation |
InterPro:IPR000719,InterPro:IPR017441,InterPro:IPR017442,InterPro:IPR002290 |
F |
From MGI |
||
| GO:0005634 |
nucleus |
MGI:MGI:3590381 |
ISO: Inferred from Sequence Orthology |
C |
From MGI |
|||
| GO:0006468 |
protein amino acid phosphorylation |
MGI:MGI:2384369 |
IDA: Inferred from Direct Assay |
P |
From MGI |
|||
| GO:0006468 |
protein amino acid phosphorylation |
MGI:MGI:3836857 |
IDA: Inferred from Direct Assay |
P |
From MGI |
|||
| GO:0007049 |
cell cycle |
MGI:MGI:1354194 |
IEA: Inferred from Electronic Annotation |
P |
From MGI |
|||
| GO:0007067 |
mitosis |
MGI:MGI:1354194 |
IEA: Inferred from Electronic Annotation |
P |
From MGI |
|||
| GO:0007095 |
mitotic cell cycle G2/M transition DNA damage checkpoint |
MGI:MGI:2679752 |
IDA: Inferred from Direct Assay |
P |
From MGI |
|||
| GO:0008353 |
RNA polymerase II carboxy-terminal domain kinase activity |
MGI:MGI:2152096 |
IEA: Inferred from Electronic Annotation |
F |
From MGI |
|||
| GO:0016301 |
kinase activity |
MGI:MGI:2384369 |
IDA: Inferred from Direct Assay |
F |
From MGI |
|||
| GO:0016301 |
kinase activity |
MGI:MGI:2679752 |
IDA: Inferred from Direct Assay |
F |
From MGI |
|||
| GO:0016740 |
transferase activity |
MGI:MGI:1354194 |
IEA: Inferred from Electronic Annotation |
F |
From MGI |
|||
| GO:0030544 |
Hsp70 protein binding |
MGI:MGI:2181827 |
IPI: Inferred from Physical Interaction |
F |
From MGI |
|||
| GO:0051301 |
cell division |
MGI:MGI:1354194 |
IEA: Inferred from Electronic Annotation |
P |
From MGI |
| ||
| edit table |
Notes
References
See Help:References for how to manage references in GONUTS.
- ↑ Jang MK et al. (2005) The bromodomain protein Brd4 is a positive regulatory component of P-TEFb and stimulates RNA polymerase II-dependent transcription. Mol Cell 19: 523-34 PubMed GONUTS page
- ↑ 2.0 2.1 Vairapandi M et al. (2002) GADD45b and GADD45g are cdc2/cyclinB1 kinase inhibitors with a role in S and G2/M cell cycle checkpoints induced by genotoxic stress. J Cell Physiol 192: 327-38 PubMed GONUTS page
- ↑ Wang X et al. (2009) Mitochondrial degeneration and not apoptosis is the primary cause of embryonic lethality in ceramide transfer protein mutant mice. J Cell Biol 184: 143-58 PubMed GONUTS page
- ↑ 4.0 4.1 Yuan L et al. (2003) DNA damage-induced G2/M checkpoint in SV40 large T antigen-immortalized embryonic fibroblast cells requires SHP-2 tyrosine phosphatase. J Biol Chem 278: 42812-20 PubMed GONUTS page
- ↑ Zhu D et al. (1997) HSP70-2 is required for CDC2 kinase activity in meiosis I of mouse spermatocytes. Development 124: 3007-14 PubMed GONUTS page
