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MGI:Cd24a

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Contents

Species (Taxon ID) Mus musculus (house mouse) (taxon:10090)
Gene Name(s) Cd24a ( synonyms: cluster of differentiation 24, heat stable antigen, HSA, Ly-52, nectadrin )
Protein Name(s) CD24a antigen,
External Links
MGI MGI:88323

Annotations

Qualifier GO ID GO term name Reference Evidence Code with/from Aspect Notes Status
GO:0001666

response to hypoxia

MGI:MGI:3759199
PMID:15174142[1]

ISS: Inferred from Sequence or Structural Similarity

UniProtKB:P25063

P

From MGI

GO:0001775

cell activation

MGI:MGI:3759362
PMID:8223854[2]

ISS: Inferred from Sequence or Structural Similarity

UniProtKB:P25063

P

From MGI

GO:0001775

cell activation

MGI:MGI:4834177

ISO: Inferred from Sequence Orthology

UniProtKB:P25063

P

From MGI

GO:0001934

positive regulation of protein phosphorylation

MGI:MGI:4834177

ISO: Inferred from Sequence Orthology

UniProtKB:P25063

P

From MGI

GO:0001959

regulation of cytokine-mediated signaling pathway

MGI:MGI:3614932
PMID:16390867[3]

IMP: Inferred from Mutant Phenotype

P

From MGI

GO:0002237

response to molecule of bacterial origin

MGI:MGI:3759338
PMID:15493995[4]

IDA: Inferred from Direct Assay

P

From MGI

GO:0002329

pre-B cell differentiation

MGI:MGI:2179980
PMID:9028339[5]

IMP: Inferred from Mutant Phenotype

MGI:MGI:2179996

P

From MGI

GO:0002329

pre-B cell differentiation

MGI:MGI:74794
PMID:7795661[6]

IMP: Inferred from Mutant Phenotype

MGI:MGI:2179996

P

From MGI

GO:0002523

leukocyte migration involved in inflammatory response

MGI:MGI:3510282
PMID:15314074[7]

IMP: Inferred from Mutant Phenotype

MGI:MGI:2179996

P

From MGI

GO:0002842

positive regulation of T cell mediated immune response to tumor cell

MGI:MGI:73458
PMID:7774619[8]

IDA: Inferred from Direct Assay

P

From MGI

GO:0002863

positive regulation of inflammatory response to antigenic stimulus

MGI:MGI:3510282
PMID:15314074[7]

IMP: Inferred from Mutant Phenotype

MGI:MGI:2179996

P

From MGI

GO:0002863

positive regulation of inflammatory response to antigenic stimulus

MGI:MGI:3706650
PMID:10791997[9]

IMP: Inferred from Mutant Phenotype

MGI:MGI:2179996

P

From MGI

GO:0002904

positive regulation of B cell apoptotic process

MGI:MGI:3757615
PMID:8920854[10]

IDA: Inferred from Direct Assay

P

From MGI

GO:0005622

intracellular

MGI:MGI:3614932
PMID:16390867[3]

IMP: Inferred from Mutant Phenotype

C

From MGI

GO:0005622

intracellular

MGI:MGI:4834177

ISO: Inferred from Sequence Orthology

UniProtKB:P25063

C

From MGI

GO:0005624

membrane fraction

MGI:MGI:3706622
PMID:11283023[11]

IDA: Inferred from Direct Assay

C

From MGI

GO:0005886

plasma membrane

MGI:MGI:2178911
PMID:11978835[12]

IDA: Inferred from Direct Assay

C

From MGI

GO:0007157

heterophilic cell-cell adhesion

MGI:MGI:3757618
PMID:8562500[13]

IDA: Inferred from Direct Assay

P

From MGI

GO:0007157

heterophilic cell-cell adhesion

MGI:MGI:3757621
PMID:8145052[14]

IDA: Inferred from Direct Assay

P

From MGI

GO:0007159

leukocyte cell-cell adhesion

MGI:MGI:3757617
PMID:8557754[15]

IDA: Inferred from Direct Assay

P

From MGI

GO:0007159

leukocyte cell-cell adhesion

MGI:MGI:3757618
PMID:8562500[13]

IDA: Inferred from Direct Assay

P

From MGI

GO:0007159

leukocyte cell-cell adhesion

MGI:MGI:3757620
PMID:7534304[16]

IDA: Inferred from Direct Assay

P

From MGI

GO:0007159

leukocyte cell-cell adhesion

MGI:MGI:3757623
PMID:8117278[17]

IDA: Inferred from Direct Assay

P

From MGI

GO:0007159

leukocyte cell-cell adhesion

MGI:MGI:87805
PMID:9177270[18]

IDA: Inferred from Direct Assay

P

From MGI

GO:0007166

cell surface receptor signaling pathway

MGI:MGI:3757623
PMID:8117278[17]

IDA: Inferred from Direct Assay

P

From MGI

GO:0007166

cell surface receptor signaling pathway

MGI:MGI:74049
PMID:7613634[19]

IDA: Inferred from Direct Assay

P

From MGI

GO:0007166

cell surface receptor signaling pathway

MGI:MGI:87805
PMID:9177270[18]

IDA: Inferred from Direct Assay

P

From MGI

GO:0007204

elevation of cytosolic calcium ion concentration

MGI:MGI:3759362
PMID:8223854[2]

ISS: Inferred from Sequence or Structural Similarity

UniProtKB:P25063

P

From MGI

GO:0007204

elevation of cytosolic calcium ion concentration

MGI:MGI:3759363
PMID:2153173[20]

ISS: Inferred from Sequence or Structural Similarity

UniProtKB:P25063

P

From MGI

GO:0007204

elevation of cytosolic calcium ion concentration

MGI:MGI:4834177

ISO: Inferred from Sequence Orthology

UniProtKB:P25063

P

From MGI

GO:0007274

neuromuscular synaptic transmission

MGI:MGI:3625625
PMID:16606832[21]

IGI: Inferred from Genetic Interaction

MGI:MGI:2139434

P

From MGI

GO:0007274

neuromuscular synaptic transmission

MGI:MGI:3625625
PMID:16606832[21]

IMP: Inferred from Mutant Phenotype

MGI:MGI:2179996

P

From MGI

GO:0007406

negative regulation of neuroblast proliferation

MGI:MGI:2178911
PMID:11978835[12]

IMP: Inferred from Mutant Phenotype

MGI:MGI:2179996

P

From MGI

GO:0008624

induction of apoptosis by extracellular signals

MGI:MGI:2686748
PMID:14707049[22]

IDA: Inferred from Direct Assay

P

From MGI

GO:0008624

induction of apoptosis by extracellular signals

MGI:MGI:3757615
PMID:8920854[10]

IDA: Inferred from Direct Assay

P

From MGI

GO:0008624

induction of apoptosis by extracellular signals

MGI:MGI:3757616
PMID:8943715[23]

IDA: Inferred from Direct Assay

P

From MGI

GO:0008637

apoptotic mitochondrial changes

MGI:MGI:2686748
PMID:14707049[22]

IDA: Inferred from Direct Assay

P

From MGI

GO:0009897

external side of plasma membrane

MGI:MGI:1338599
PMID:10365441[24]

IDA: Inferred from Direct Assay

C

From MGI

GO:0009897

external side of plasma membrane

MGI:MGI:1860996
PMID:10943842[25]

IDA: Inferred from Direct Assay

C

From MGI

GO:0009897

external side of plasma membrane

MGI:MGI:2154458

ISO: Inferred from Sequence Orthology

UniProtKB:Q07490

C

From MGI

GO:0009897

external side of plasma membrane

MGI:MGI:2179980
PMID:9028339[5]

IDA: Inferred from Direct Assay

C

From MGI

GO:0009897

external side of plasma membrane

MGI:MGI:2670820
PMID:12882831[26]

IDA: Inferred from Direct Assay

C

From MGI

GO:0009897

external side of plasma membrane

MGI:MGI:2686748
PMID:14707049[22]

IDA: Inferred from Direct Assay

C

From MGI

GO:0009897

external side of plasma membrane

MGI:MGI:3039545
PMID:12940824[27]

IDA: Inferred from Direct Assay

C

From MGI

GO:0009897

external side of plasma membrane

MGI:MGI:3041277
PMID:14990792[28]

IDA: Inferred from Direct Assay

C

From MGI

GO:0009897

external side of plasma membrane

MGI:MGI:3510282
PMID:15314074[7]

IDA: Inferred from Direct Assay

C

From MGI

GO:0009897

external side of plasma membrane

MGI:MGI:3510302
PMID:15477346[29]

IDA: Inferred from Direct Assay

C

From MGI

GO:0009897

external side of plasma membrane

MGI:MGI:3757615
PMID:8920854[10]

IDA: Inferred from Direct Assay

C

From MGI

GO:0009897

external side of plasma membrane

MGI:MGI:3757617
PMID:8557754[15]

IDA: Inferred from Direct Assay

C

From MGI

GO:0009897

external side of plasma membrane

MGI:MGI:3757620
PMID:7534304[16]

IDA: Inferred from Direct Assay

C

From MGI

GO:0009897

external side of plasma membrane

MGI:MGI:3757621
PMID:8145052[14]

IDA: Inferred from Direct Assay

C

From MGI

GO:0009897

external side of plasma membrane

MGI:MGI:3757622
PMID:7908303[30]

IDA: Inferred from Direct Assay

C

From MGI

GO:0009897

external side of plasma membrane

MGI:MGI:3757624
PMID:1385153[31]

IDA: Inferred from Direct Assay

C

From MGI

GO:0009897

external side of plasma membrane

MGI:MGI:3757626
PMID:1346270[32]

IDA: Inferred from Direct Assay

C

From MGI

GO:0009897

external side of plasma membrane

MGI:MGI:3817343
PMID:18776904[33]

IDA: Inferred from Direct Assay

C

From MGI

GO:0009897

external side of plasma membrane

MGI:MGI:3829828
PMID:18958875[34]

IDA: Inferred from Direct Assay

C

From MGI

GO:0009897

external side of plasma membrane

MGI:MGI:4439000
PMID:20103531[35]

IDA: Inferred from Direct Assay

C

From MGI

GO:0009897

external side of plasma membrane

MGI:MGI:4821247
PMID:19487454[36]

IDA: Inferred from Direct Assay

C

From MGI

GO:0009897

external side of plasma membrane

MGI:MGI:51393
PMID:1383383[37]

IDA: Inferred from Direct Assay

C

From MGI

GO:0009897

external side of plasma membrane

MGI:MGI:59144
PMID:2118158[38]

IDA: Inferred from Direct Assay

C

From MGI

GO:0009897

external side of plasma membrane

MGI:MGI:65397
PMID:8125140[39]

IDA: Inferred from Direct Assay

C

From MGI

GO:0009897

external side of plasma membrane

MGI:MGI:70338
PMID:7807014[40]

IDA: Inferred from Direct Assay

C

From MGI

GO:0009897

external side of plasma membrane

MGI:MGI:73458
PMID:7774619[8]

IDA: Inferred from Direct Assay

C

From MGI

GO:0009897

external side of plasma membrane

MGI:MGI:74049
PMID:7613634[19]

IDA: Inferred from Direct Assay

C

From MGI

GO:0009897

external side of plasma membrane

MGI:MGI:74794
PMID:7795661[6]

IDA: Inferred from Direct Assay

C

From MGI

GO:0009897

external side of plasma membrane

MGI:MGI:77314
PMID:7477352[41]

IDA: Inferred from Direct Assay

C

From MGI

GO:0009897

external side of plasma membrane

MGI:MGI:78046
PMID:8543797[42]

IDA: Inferred from Direct Assay

C

From MGI

GO:0009986

cell surface

MGI:MGI:1097217
PMID:9324354[43]

IDA: Inferred from Direct Assay

C

From MGI

GO:0009986

cell surface

MGI:MGI:4834177

ISO: Inferred from Sequence Orthology

UniProtKB:P25063

C

From MGI

GO:0010976

positive regulation of neuron projection development

MGI:MGI:4438147
PMID:19458237[44]

IDA: Inferred from Direct Assay

P

From MGI

GO:0010976

positive regulation of neuron projection development

MGI:MGI:4438147
PMID:19458237[44]

IGI: Inferred from Genetic Interaction

MGI:MGI:104518
MGI:MGI:105980

P

From MGI

GO:0016020

membrane

MGI:MGI:3759344
PMID:10037815[45]

ISS: Inferred from Sequence or Structural Similarity

UniProtKB:P25063

C

From MGI

GO:0016020

membrane

MGI:MGI:4834177

ISO: Inferred from Sequence Orthology

UniProtKB:P25063

C

From MGI

GO:0016477

cell migration

MGI:MGI:3614932
PMID:16390867[3]

IMP: Inferred from Mutant Phenotype

P

From MGI

GO:0019901

protein kinase binding

MGI:MGI:3759346
PMID:8753773[46]

ISS: Inferred from Sequence or Structural Similarity

UniProtKB:P25063

F

From MGI

GO:0019901

protein kinase binding

MGI:MGI:4834177

ISO: Inferred from Sequence Orthology

UniProtKB:P25063

F

From MGI

GO:0022407

regulation of cell-cell adhesion

MGI:MGI:3757623
PMID:8117278[17]

IDA: Inferred from Direct Assay

P

From MGI

GO:0022409

positive regulation of cell-cell adhesion

MGI:MGI:3757617
PMID:8557754[15]

IDA: Inferred from Direct Assay

P

From MGI

GO:0022409

positive regulation of cell-cell adhesion

MGI:MGI:3757619
PMID:7669058[47]

IDA: Inferred from Direct Assay

P

From MGI

GO:0022409

positive regulation of cell-cell adhesion

MGI:MGI:87805
PMID:9177270[18]

IDA: Inferred from Direct Assay

P

From MGI

GO:0030246

carbohydrate binding

MGI:MGI:3759177
PMID:15633604[48]

IDA: Inferred from Direct Assay

F

From MGI

GO:0030262

apoptotic nuclear change

MGI:MGI:2686748
PMID:14707049[22]

IDA: Inferred from Direct Assay

P

From MGI

GO:0030296

protein tyrosine kinase activator activity

MGI:MGI:3759342
PMID:11313396[49]

ISS: Inferred from Sequence or Structural Similarity

UniProtKB:P25063

F

From MGI

GO:0030296

protein tyrosine kinase activator activity

MGI:MGI:4834177

ISO: Inferred from Sequence Orthology

UniProtKB:P25063

F

From MGI

GO:0030889

negative regulation of B cell proliferation

MGI:MGI:3757615
PMID:8920854[10]

IDA: Inferred from Direct Assay

P

From MGI

GO:0031175

neuron projection development

MGI:MGI:3706622
PMID:11283023[11]

IDA: Inferred from Direct Assay

P

From MGI

GO:0031175

neuron projection development

MGI:MGI:3706622
PMID:11283023[11]

IMP: Inferred from Mutant Phenotype

MGI:MGI:2179996

P

From MGI

GO:0031225

anchored to membrane

MGI:MGI:1354194

IEA: Inferred from Electronic Annotation

UniProtKB-KW:KW-0336

C

From MGI

GO:0031295

T cell costimulation

MGI:MGI:3759343
PMID:11272271[50]

ISS: Inferred from Sequence or Structural Similarity

UniProtKB:P25063

P

From MGI

GO:0031295

T cell costimulation

MGI:MGI:4834177

ISO: Inferred from Sequence Orthology

UniProtKB:P25063

P

From MGI

GO:0031362

anchored to external side of plasma membrane

MGI:MGI:2154458

ISO: Inferred from Sequence Orthology

UniProtKB:Q07490

C

From MGI

GO:0031362

anchored to external side of plasma membrane

MGI:MGI:2686748
PMID:14707049[22]

IDA: Inferred from Direct Assay

C

From MGI

GO:0031362

anchored to external side of plasma membrane

MGI:MGI:3757622
PMID:7908303[30]

IDA: Inferred from Direct Assay

C

From MGI

GO:0031362

anchored to external side of plasma membrane

MGI:MGI:3757626
PMID:1346270[32]

IDA: Inferred from Direct Assay

C

From MGI

GO:0031362

anchored to external side of plasma membrane

MGI:MGI:59144
PMID:2118158[38]

IDA: Inferred from Direct Assay

C

From MGI

GO:0031362

anchored to external side of plasma membrane

MGI:MGI:65397
PMID:8125140[39]

IDA: Inferred from Direct Assay

C

From MGI

GO:0031528

microvillus membrane

MGI:MGI:2178911
PMID:11978835[12]

IDA: Inferred from Direct Assay

C

From MGI

GO:0032597

B cell receptor transport into membrane raft

MGI:MGI:4834177

ISO: Inferred from Sequence Orthology

UniProtKB:P25063

P

From MGI

GO:0032600

chemokine receptor transport out of membrane raft

MGI:MGI:3614932
PMID:16390867[3]

IMP: Inferred from Mutant Phenotype

P

From MGI

GO:0032913

negative regulation of transforming growth factor beta3 production

MGI:MGI:3759334
PMID:16930538[51]

ISS: Inferred from Sequence or Structural Similarity

UniProtKB:P25063

P

From MGI

GO:0032913

negative regulation of transforming growth factor beta3 production

MGI:MGI:4834177

ISO: Inferred from Sequence Orthology

UniProtKB:P25063

P

From MGI

GO:0033625

positive regulation of integrin activation

MGI:MGI:3757613
PMID:10601245[52]

IDA: Inferred from Direct Assay

P

From MGI

GO:0033625

positive regulation of integrin activation

MGI:MGI:3757613
PMID:10601245[52]

IMP: Inferred from Mutant Phenotype

MGI:MGI:2179996

P

From MGI

GO:0033625

positive regulation of integrin activation

MGI:MGI:3757620
PMID:7534304[16]

IDA: Inferred from Direct Assay

P

From MGI

GO:0033630

positive regulation of cell adhesion mediated by integrin

MGI:MGI:3757613
PMID:10601245[52]

IDA: Inferred from Direct Assay

P

From MGI

GO:0033630

positive regulation of cell adhesion mediated by integrin

MGI:MGI:3757613
PMID:10601245[52]

IMP: Inferred from Mutant Phenotype

MGI:MGI:2179996

P

From MGI

GO:0033632

regulation of cell-cell adhesion mediated by integrin

MGI:MGI:3757621
PMID:8145052[14]

IDA: Inferred from Direct Assay

P

From MGI

GO:0033634

positive regulation of cell-cell adhesion mediated by integrin

MGI:MGI:3757620
PMID:7534304[16]

IDA: Inferred from Direct Assay

P

From MGI

GO:0034107

negative regulation of erythrocyte clearance

MGI:MGI:2179980
PMID:9028339[5]

IMP: Inferred from Mutant Phenotype

MGI:MGI:2179996

P

From MGI

GO:0034109

homotypic cell-cell adhesion

MGI:MGI:74049
PMID:7613634[19]

IMP: Inferred from Mutant Phenotype

P

From MGI

GO:0034119

negative regulation of erythrocyte aggregation

MGI:MGI:2179980
PMID:9028339[5]

IMP: Inferred from Mutant Phenotype

MGI:MGI:2179996

P

From MGI

GO:0042103

positive regulation of T cell homeostatic proliferation

MGI:MGI:3510302
PMID:15477346[29]

IMP: Inferred from Mutant Phenotype

MGI:MGI:2179996

P

From MGI

GO:0042104

positive regulation of activated T cell proliferation

MGI:MGI:3759343
PMID:11272271[50]

ISS: Inferred from Sequence or Structural Similarity

UniProtKB:P25063

P

From MGI

GO:0042104

positive regulation of activated T cell proliferation

MGI:MGI:4834177

ISO: Inferred from Sequence Orthology

UniProtKB:P25063

P

From MGI

GO:0042325

regulation of phosphorylation

MGI:MGI:3759342
PMID:11313396[49]

ISS: Inferred from Sequence or Structural Similarity

UniProtKB:P25063

P

From MGI

GO:0042325

regulation of phosphorylation

MGI:MGI:4834177

ISO: Inferred from Sequence Orthology

UniProtKB:P25063

P

From MGI

GO:0042632

cholesterol homeostasis

MGI:MGI:3614932
PMID:16390867[3]

IMP: Inferred from Mutant Phenotype

P

From MGI

GO:0043406

positive regulation of MAP kinase activity

MGI:MGI:3759341
PMID:12496407[53]

ISS: Inferred from Sequence or Structural Similarity

UniProtKB:P25063

P

From MGI

GO:0043406

positive regulation of MAP kinase activity

MGI:MGI:4834177

ISO: Inferred from Sequence Orthology

UniProtKB:P25063

P

From MGI

GO:0043408

regulation of MAPK cascade

MGI:MGI:3759342
PMID:11313396[49]

ISS: Inferred from Sequence or Structural Similarity

UniProtKB:P25063

P

From MGI

GO:0043408

regulation of MAPK cascade

MGI:MGI:4834177

ISO: Inferred from Sequence Orthology

UniProtKB:P25063

P

From MGI

GO:0043499

eukaryotic cell surface binding

MGI:MGI:51393
PMID:1383383[37]

IDA: Inferred from Direct Assay

F

From MGI

GO:0043627

response to estrogen stimulus

MGI:MGI:3759344
PMID:10037815[45]

ISS: Inferred from Sequence or Structural Similarity

UniProtKB:P25063

P

From MGI

GO:0045121

membrane raft

MGI:MGI:3759338
PMID:15493995[4]

IDA: Inferred from Direct Assay

C

From MGI

GO:0045121

membrane raft

MGI:MGI:3759342
PMID:11313396[49]

ISS: Inferred from Sequence or Structural Similarity

UniProtKB:P25063

C

From MGI

GO:0045121

membrane raft

MGI:MGI:4834177

ISO: Inferred from Sequence Orthology

UniProtKB:P25063

C

From MGI

GO:0045577

regulation of B cell differentiation

MGI:MGI:2179980
PMID:9028339[5]

IMP: Inferred from Mutant Phenotype

MGI:MGI:2179996

P

From MGI

GO:0045577

regulation of B cell differentiation

MGI:MGI:74794
PMID:7795661[6]

IMP: Inferred from Mutant Phenotype

MGI:MGI:2179996

P

From MGI

GO:0045665

negative regulation of neuron differentiation

MGI:MGI:3757612
PMID:15737737[54]

IMP: Inferred from Mutant Phenotype

MGI:MGI:2179996

P

From MGI

GO:0045730

respiratory burst

MGI:MGI:3759362
PMID:8223854[2]

ISS: Inferred from Sequence or Structural Similarity

UniProtKB:P25063

P

From MGI

GO:0045730

respiratory burst

MGI:MGI:4834177

ISO: Inferred from Sequence Orthology

UniProtKB:P25063

P

From MGI

GO:0046014

negative regulation of T cell homeostatic proliferation

MGI:MGI:3721471
PMID:16769998[55]

IMP: Inferred from Mutant Phenotype

MGI:MGI:2179996

P

From MGI

GO:0046641

positive regulation of alpha-beta T cell proliferation

MGI:MGI:3510282
PMID:15314074[7]

IMP: Inferred from Mutant Phenotype

MGI:MGI:2179996

P

From MGI

GO:0046641

positive regulation of alpha-beta T cell proliferation

MGI:MGI:3757614
PMID:9368605[56]

IDA: Inferred from Direct Assay

P

From MGI

GO:0046641

positive regulation of alpha-beta T cell proliferation

MGI:MGI:3757614
PMID:9368605[56]

IMP: Inferred from Mutant Phenotype

MGI:MGI:2179996

P

From MGI

GO:0046641

positive regulation of alpha-beta T cell proliferation

MGI:MGI:3757622
PMID:7908303[30]

IMP: Inferred from Mutant Phenotype

P

From MGI

GO:0046641

positive regulation of alpha-beta T cell proliferation

MGI:MGI:3757624
PMID:1385153[31]

IMP: Inferred from Mutant Phenotype

P

From MGI

GO:0046641

positive regulation of alpha-beta T cell proliferation

MGI:MGI:3757626
PMID:1346270[32]

IDA: Inferred from Direct Assay

P

From MGI

GO:0046641

positive regulation of alpha-beta T cell proliferation

MGI:MGI:65397
PMID:8125140[39]

IDA: Inferred from Direct Assay

P

From MGI

GO:0048488

synaptic vesicle endocytosis

MGI:MGI:3625625
PMID:16606832[21]

IMP: Inferred from Mutant Phenotype

MGI:MGI:2179996

P

From MGI

GO:0050731

positive regulation of peptidyl-tyrosine phosphorylation

MGI:MGI:3757613
PMID:10601245[52]

IDA: Inferred from Direct Assay

P

From MGI

GO:0050731

positive regulation of peptidyl-tyrosine phosphorylation

MGI:MGI:87805
PMID:9177270[18]

IDA: Inferred from Direct Assay

P

From MGI

GO:0050768

negative regulation of neurogenesis

MGI:MGI:3757612
PMID:15737737[54]

IMP: Inferred from Mutant Phenotype

MGI:MGI:2179996

P

From MGI

GO:0050850

positive regulation of calcium-mediated signaling

MGI:MGI:3757623
PMID:8117278[17]

IDA: Inferred from Direct Assay

P

From MGI

GO:0050850

positive regulation of calcium-mediated signaling

MGI:MGI:74049
PMID:7613634[19]

IDA: Inferred from Direct Assay

P

From MGI

GO:0060170

cilium membrane

MGI:MGI:2178911
PMID:11978835[12]

IDA: Inferred from Direct Assay

C

From MGI

GO:0061098

positive regulation of protein tyrosine kinase activity

MGI:MGI:4834177

ISO: Inferred from Sequence Orthology

UniProtKB:P25063

P

From MGI

GO:0072112

glomerular visceral epithelial cell differentiation

MGI:MGI:4834177

ISO: Inferred from Sequence Orthology

UniProtKB:P25063

P

From MGI

GO:0072139

glomerular parietal epithelial cell differentiation

MGI:MGI:4834177

ISO: Inferred from Sequence Orthology

UniProtKB:P25063

P

From MGI

GO:2000768

positive regulation of nephron tubule epithelial cell differentiation

MGI:MGI:4834177

ISO: Inferred from Sequence Orthology

UniProtKB:P25063

P

From MGI


Notes

References

See Help:References for how to manage references in GONUTS.
  1. ↑ Scheurer SB et al. (2004) Modulation of gene expression by hypoxia in human umbilical cord vein endothelial cells: A transcriptomic and proteomic study. Proteomics 4: 1737-60 PubMed GONUTS page
  2. ↑ 2.0 2.1 2.2 Lund-Johansen F et al. (1993) Activation of human monocytes and granulocytes by monoclonal antibodies to glycosylphosphatidylinositol-anchored antigens. Eur J Immunol 23: 2782-91 PubMed GONUTS page
  3. ↑ 3.0 3.1 3.2 3.3 3.4 Schabath H et al. (2006) CD24 affects CXCR4 function in pre-B lymphocytes and breast carcinoma cells. J Cell Sci 119: 314-25 PubMed GONUTS page
  4. ↑ 4.0 4.1 Gekara NO & Weiss S (2004) Lipid rafts clustering and signalling by listeriolysin O. Biochem Soc Trans 32: 712-4 PubMed GONUTS page
  5. ↑ 5.0 5.1 5.2 5.3 5.4 Nielsen PJ et al. (1997) Altered erythrocytes and a leaky block in B-cell development in CD24/HSA-deficient mice. Blood 89: 1058-67 PubMed GONUTS page
  6. ↑ 6.0 6.1 6.2 Wenger RH et al. (1995) B-cell maturation in chimaeric mice deficient for the heat stable antigen (HSA/mouse CD24). Transgenic Res 4: 173-83 PubMed GONUTS page
  7. ↑ 7.0 7.1 7.2 7.3 Bai XF et al. (2004) CD24 controls expansion and persistence of autoreactive T cells in the central nervous system during experimental autoimmune encephalomyelitis. J Exp Med 200: 447-58 PubMed GONUTS page
  8. ↑ 8.0 8.1 Wang YC et al. (1995) Expression of heat-stable antigen on tumor cells provides co-stimulation for tumor-specific T cell proliferation and cytotoxicity in mice. Eur J Immunol 25: 1163-7 PubMed GONUTS page
  9. ↑ Bai XF et al. (2000) The heat-stable antigen determines pathogenicity of self-reactive T cells in experimental autoimmune encephalomyelitis. J Clin Invest 105: 1227-32 PubMed GONUTS page
  10. ↑ 10.0 10.1 10.2 10.3 Chappel MS et al. (1996) Cross-linking the murine heat-stable antigen induces apoptosis in B cell precursors and suppresses the anti-CD40-induced proliferation of mature resting B lymphocytes. J Exp Med 184: 1639-49 PubMed GONUTS page
  11. ↑ 11.0 11.1 11.2 Kleene R et al. (2001) The neural recognition molecule L1 is a sialic acid-binding lectin for CD24, which induces promotion and inhibition of neurite outgrowth. J Biol Chem 276: 21656-63 PubMed GONUTS page
  12. ↑ 12.0 12.1 12.2 12.3 Belvindrah R et al. (2002) Increased neurogenesis in adult mCD24-deficient mice. J Neurosci 22: 3594-607 PubMed GONUTS page
  13. ↑ 13.0 13.1 Aigner S et al. (1995) Heat stable antigen (mouse CD24) supports myeloid cell binding to endothelial and platelet P-selectin. Int Immunol 7: 1557-65 PubMed GONUTS page
  14. ↑ 14.0 14.1 14.2 Hahne M et al. (1994) The heat-stable antigen can alter very late antigen 4-mediated adhesion. J Exp Med 179: 1391-5 PubMed GONUTS page
  15. ↑ 15.0 15.1 15.2 Ruppert M et al. (1995) The L1 adhesion molecule is a cellular ligand for VLA-5. J Cell Biol 131: 1881-91 PubMed GONUTS page
  16. ↑ 16.0 16.1 16.2 16.3 Kilger G et al. (1995) Differential regulation of alpha 4 integrin-dependent binding to domains 1 and 4 of vascular cell adhesion molecule-1. J Biol Chem 270: 5979-84 PubMed GONUTS page
  17. ↑ 17.0 17.1 17.2 17.3 Kadmon G et al. (1994) Differential, LFA-1-sensitive effects of antibodies to nectadrin, the heat-stable antigen, on B lymphoblast aggregation and signal transduction. Biochem Biophys Res Commun 198: 1209-15 PubMed GONUTS page
  18. ↑ 18.0 18.1 18.2 18.3 Sammar M et al. (1997) Mouse CD24 as a signaling molecule for integrin-mediated cell binding: functional and physical association with src-kinases. Biochem Biophys Res Commun 234: 330-4 PubMed GONUTS page
  19. ↑ 19.0 19.1 19.2 19.3 Kadmon G et al. (1995) Evidence for cis interaction and cooperative signalling by the heat-stable antigen nectadrin (murine CD24) and the cell adhesion molecule L1 in neurons. Eur J Neurosci 7: 993-1004 PubMed GONUTS page
  20. ↑ Fischer GF et al. (1990) Signal transduction in lymphocytic and myeloid cells via CD24, a new member of phosphoinositol-anchored membrane molecules. J Immunol 144: 638-41 PubMed GONUTS page
  21. ↑ 21.0 21.1 21.2 Jevsek M et al. (2006) CD24 is expressed by myofiber synaptic nuclei and regulates synaptic transmission. Proc Natl Acad Sci U S A 103: 6374-9 PubMed GONUTS page
  22. ↑ 22.0 22.1 22.2 22.3 22.4 Jung KC et al. (2004) TCR-independent and caspase-independent apoptosis of murine thymocytes by CD24 cross-linking. J Immunol 172: 795-802 PubMed GONUTS page
  23. ↑ Hitsumoto Y et al. (1996) Enhancement of CD3-mediated thymocyte apoptosis by the cross-linkage of heat-stable antigen. Immunology 89: 200-4 PubMed GONUTS page
  24. ↑ Cram DS et al. (1999) Differential mRNA display analysis of two related but functionally distinct rat insulinoma (RIN) cell lines: identification of CD24 and its expression in the developing pancreas. Differentiation 64: 237-46 PubMed GONUTS page
  25. ↑ Tamura K et al. (2000) Requirement for p38alpha in erythropoietin expression: a role for stress kinases in erythropoiesis. Cell 102: 221-31 PubMed GONUTS page
  26. ↑ Gerth AJ et al. (2003) T-bet regulates T-independent IgG2a class switching. Int Immunol 15: 937-44 PubMed GONUTS page
  27. ↑ Arimitsu N et al. (2003) Glycophorin A requirement for expression of O-linked antigens on the erythrocyte membrane. Genes Cells 8: 769-77 PubMed GONUTS page
  28. ↑ Carlyle JR et al. (2004) Missing self-recognition of Ocil/Clr-b by inhibitory NKR-P1 natural killer cell receptors. Proc Natl Acad Sci U S A 101: 3527-32 PubMed GONUTS page
  29. ↑ 29.0 29.1 Li O et al. (2004) CD24 expression on T cells is required for optimal T cell proliferation in lymphopenic host. J Exp Med 200: 1083-9 PubMed GONUTS page
  30. ↑ 30.0 30.1 30.2 Enk AH & Katz SI (1994) Heat-stable antigen is an important costimulatory molecule on epidermal Langerhans' cells. J Immunol 152: 3264-70 PubMed GONUTS page
  31. ↑ 31.0 31.1 Liu Y et al. (1992) Co-stimulation of murine CD4 T cell growth: cooperation between B7 and heat-stable antigen. Eur J Immunol 22: 2855-9 PubMed GONUTS page
  32. ↑ 32.0 32.1 32.2 Liu Y et al. (1992) Heat-stable antigen is a costimulatory molecule for CD4 T cell growth. J Exp Med 175: 437-45 PubMed GONUTS page
  33. ↑ Wang L et al. (2008) Distinct functions for the transcription factors GATA-3 and ThPOK during intrathymic differentiation of CD4(+) T cells. Nat Immunol 9: 1122-30 PubMed GONUTS page
  34. ↑ Jia J et al. (2008) E proteins are required to activate germline transcription of the TCR Vbeta8.2 gene. Eur J Immunol 38: 2806-20 PubMed GONUTS page
  35. ↑ Greene SB et al. (2010) A putative role for microRNA-205 in mammary epithelial cell progenitors. J Cell Sci 123: 606-18 PubMed GONUTS page
  36. ↑ Gu B et al. (2009) Pygo2 expands mammary progenitor cells by facilitating histone H3 K4 methylation. J Cell Biol 185: 811-26 PubMed GONUTS page
  37. ↑ 37.0 37.1 Kato K et al. (1992) CD48 is a counter-receptor for mouse CD2 and is involved in T cell activation. J Exp Med 176: 1241-9 PubMed GONUTS page
  38. ↑ 38.0 38.1 Kay R et al. (1990) Expression cloning of a cDNA encoding M1/69-J11d heat-stable antigens. J Immunol 145: 1952-9 PubMed GONUTS page
  39. ↑ 39.0 39.1 39.2 Hubbe M & Altevogt P (1994) Heat-stable antigen/CD24 on mouse T lymphocytes: evidence for a costimulatory function. Eur J Immunol 24: 731-7 PubMed GONUTS page
  40. ↑ Kawai K et al. (1995) Impaired development of V gamma 3 dendritic epidermal T cells in p56lck protein tyrosine kinase-deficient and CD45 protein tyrosine phosphatase-deficient mice. J Exp Med 181: 345-9 PubMed GONUTS page
  41. ↑ Turner M et al. (1995) Perinatal lethality and blocked B-cell development in mice lacking the tyrosine kinase Syk. Nature 378: 298-302 PubMed GONUTS page
  42. ↑ Hough MR et al. (1996) Reduction of early B lymphocyte precursors in transgenic mice overexpressing the murine heat-stable antigen. J Immunol 156: 479-88 PubMed GONUTS page
  43. ↑ Yoder MC et al. (1997) Characterization of definitive lymphohematopoietic stem cells in the day 9 murine yolk sac. Immunity 7: 335-44 PubMed GONUTS page
  44. ↑ 44.0 44.1 Lieberoth A et al. (2009) Lewis(x) and alpha2,3-sialyl glycans and their receptors TAG-1, Contactin, and L1 mediate CD24-dependent neurite outgrowth. J Neurosci 29: 6677-90 PubMed GONUTS page
  45. ↑ 45.0 45.1 Yang GP et al. (1999) Combining SSH and cDNA microarrays for rapid identification of differentially expressed genes. Nucleic Acids Res 27: 1517-23 PubMed GONUTS page
  46. ↑ Zarn JA et al. (1996) Association of CD24 with the kinase c-fgr in a small cell lung cancer cell line and with the kinase lyn in an erythroleukemia cell line. Biochem Biophys Res Commun 225: 384-91 PubMed GONUTS page
  47. ↑ Kadmon G et al. (1995) Adhesive hierarchy involving the cell adhesion molecules L1, CD24, and alpha 6 integrin in murine neuroblastoma N2A cells. Biochem Biophys Res Commun 214: 94-101 PubMed GONUTS page
  48. ↑ Chen C et al. (2004) Inhibition of human CD24 binding to platelet-bound P-selectin by monoclonal antibody. Proc West Pharmacol Soc 47: 28-9 PubMed GONUTS page
  49. ↑ 49.0 49.1 49.2 49.3 Suzuki T et al. (2001) CD24 induces apoptosis in human B cells via the glycolipid-enriched membrane domains/rafts-mediated signaling system. J Immunol 166: 5567-77 PubMed GONUTS page
  50. ↑ 50.0 50.1 Salamone MC et al. (2001) Antibodies recognizing CD24 LAP epitope on human T cells enhance CD28 and IL-2 T cell proliferation. J Leukoc Biol 69: 215-23 PubMed GONUTS page
  51. ↑ Ye P et al. (2006) Regulation of E-cadherin and TGF-beta3 expression by CD24 in cultured oral epithelial cells. Biochem Biophys Res Commun 349: 229-35 PubMed GONUTS page
  52. ↑ 52.0 52.1 52.2 52.3 52.4 Krauss K & Altevogt P (1999) Integrin leukocyte function-associated antigen-1-mediated cell binding can be activated by clustering of membrane rafts. J Biol Chem 274: 36921-7 PubMed GONUTS page
  53. ↑ Taguchi T et al. (2003) Pre-B cell antigen receptor-mediated signal inhibits CD24-induced apoptosis in human pre-B cells. J Immunol 170: 252-60 PubMed GONUTS page
  54. ↑ 54.0 54.1 Nieoullon V et al. (2005) mCD24 regulates proliferation of neuronal committed precursors in the subventricular zone. Mol Cell Neurosci 28: 462-74 PubMed GONUTS page
  55. ↑ Li O et al. (2006) Massive and destructive T cell response to homeostatic cue in CD24-deficient lymphopenic hosts. J Exp Med 203: 1713-20 PubMed GONUTS page
  56. ↑ 56.0 56.1 Zhou Q et al. (1997) Homotypic interaction of the heat-stable antigen is not responsible for its co-stimulatory activity for T cell clonal expansion. Eur J Immunol 27: 2524-8 PubMed GONUTS page
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