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MGI:Cd2
Contents |
| Species (Taxon ID) | Mus musculus (house mouse) (taxon:10090) | |
| Gene Name(s) | Cd2 ( synonyms: LFA-2, Ly-37, Ly37 ) | |
| Protein Name(s) | CD2 antigen, | |
| External Links | ||
| MGI | MGI:88320 | |
Annotations
| Qualifier | GO ID | GO term name | Reference | Evidence Code | with/from | Aspect | Notes | Status |
|---|---|---|---|---|---|---|---|---|
| GO:0001948 |
glycoprotein binding |
MGI:MGI:4417868 |
ISO: Inferred from Sequence Orthology |
F |
From MGI |
|||
| GO:0003823 |
antigen binding |
MGI:MGI:4417868 |
ISO: Inferred from Sequence Orthology |
F |
From MGI |
|||
| GO:0004872 |
receptor activity |
MGI:MGI:2152098 |
IEA: Inferred from Electronic Annotation |
F |
From MGI |
|||
| GO:0005515 |
protein binding |
MGI:MGI:51393 |
IPI: Inferred from Physical Interaction |
F |
From MGI |
|||
| GO:0005576 |
extracellular region |
MGI:MGI:51393 |
IDA: Inferred from Direct Assay |
C |
From MGI |
|||
| GO:0007155 |
cell adhesion |
MGI:MGI:1354194 |
IEA: Inferred from Electronic Annotation |
UniProtKB-KW:KW-0130 |
P |
From MGI |
||
| GO:0007155 |
cell adhesion |
MGI:MGI:2152098 |
IEA: Inferred from Electronic Annotation |
P |
From MGI |
|||
| GO:0009897 |
external side of plasma membrane |
MGI:MGI:3822044 |
IDA: Inferred from Direct Assay |
C |
From MGI |
|||
| GO:0009897 |
external side of plasma membrane |
MGI:MGI:5004747 |
ISO: Inferred from Sequence Orthology |
C |
From MGI |
|||
| GO:0009897 |
external side of plasma membrane |
MGI:MGI:65397 |
IDA: Inferred from Direct Assay |
C |
From MGI |
|||
| GO:0009898 |
internal side of plasma membrane |
MGI:MGI:51393 |
IDA: Inferred from Direct Assay |
C |
From MGI |
|||
| GO:0009986 |
cell surface |
MGI:MGI:4417868 |
ISO: Inferred from Sequence Orthology |
C |
From MGI |
|||
| GO:0016020 |
membrane |
MGI:MGI:1354194 |
IEA: Inferred from Electronic Annotation |
UniProtKB-KW:KW-0472 |
C |
From MGI |
||
| GO:0016021 |
integral to membrane |
MGI:MGI:1354194 |
IEA: Inferred from Electronic Annotation |
UniProtKB-KW:KW-0812 |
C |
From MGI |
||
| GO:0016021 |
integral to membrane |
MGI:MGI:2152098 |
IEA: Inferred from Electronic Annotation |
C |
From MGI |
|||
| GO:0016337 |
cell-cell adhesion |
MGI:MGI:4417868 |
ISO: Inferred from Sequence Orthology |
P |
From MGI |
|||
| GO:0019901 |
protein kinase binding |
MGI:MGI:4417868 |
ISO: Inferred from Sequence Orthology |
F |
From MGI |
|||
| GO:0030971 |
receptor tyrosine kinase binding |
MGI:MGI:4417868 |
ISO: Inferred from Sequence Orthology |
F |
From MGI |
|||
| GO:0042110 |
T cell activation |
MGI:MGI:4417868 |
ISO: Inferred from Sequence Orthology |
P |
From MGI |
|||
| GO:0042803 |
protein homodimerization activity |
MGI:MGI:4417868 |
ISO: Inferred from Sequence Orthology |
F |
From MGI |
|||
| GO:0042803 |
protein homodimerization activity |
MGI:MGI:51393 |
IDA: Inferred from Direct Assay |
F |
From MGI |
|||
| GO:0043234 |
protein complex |
MGI:MGI:4417868 |
ISO: Inferred from Sequence Orthology |
C |
From MGI |
|||
| GO:0043499 |
eukaryotic cell surface binding |
MGI:MGI:51393 |
IDA: Inferred from Direct Assay |
F |
From MGI |
|||
| GO:0043499 |
eukaryotic cell surface binding |
MGI:MGI:51393 |
IMP: Inferred from Mutant Phenotype |
F |
From MGI |
|||
| GO:0043621 |
protein self-association |
MGI:MGI:4417868 |
ISO: Inferred from Sequence Orthology |
F |
From MGI |
|||
| GO:0045121 |
membrane raft |
MGI:MGI:4417868 |
ISO: Inferred from Sequence Orthology |
C |
From MGI |
|||
| GO:0046658 |
anchored to plasma membrane |
MGI:MGI:51393 |
IDA: Inferred from Direct Assay |
C |
From MGI |
| ||
| edit table |
Notes
References
See Help:References for how to manage references in GONUTS.
- ↑ 1.0 1.1 1.2 1.3 1.4 1.5 1.6 Kato K et al. (1992) CD48 is a counter-receptor for mouse CD2 and is involved in T cell activation. J Exp Med 176: 1241-9 PubMed GONUTS page
- ↑ Butler JJ et al. (2003) Adenosine inhibits activation-induced T cell expression of CD2 and CD28 co-stimulatory molecules: role of interleukin-2 and cyclic AMP signaling pathways. J Cell Biochem 89: 975-91 PubMed GONUTS page
- ↑ Motomura Y et al. (2011) The transcription factor E4BP4 regulates the production of IL-10 and IL-13 in CD4+ T cells. Nat Immunol 12: 450-9 PubMed GONUTS page
- ↑ Hubbe M & Altevogt P (1994) Heat-stable antigen/CD24 on mouse T lymphocytes: evidence for a costimulatory function. Eur J Immunol 24: 731-7 PubMed GONUTS page