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MGI:Ccr1
Contents |
| Species (Taxon ID) | Mus musculus (house mouse) (taxon:10090) | |
| Gene Name(s) | Ccr1 ( synonyms: Cmkbr1 ) | |
| Protein Name(s) | chemokine (C-C motif) receptor 1, | |
| External Links | ||
| MGI | MGI:104618 | |
Annotations
| Qualifier | GO ID | GO term name | Reference | Evidence Code | with/from | Aspect | Notes | Status |
|---|---|---|---|---|---|---|---|---|
| GO:0004435 |
phosphatidylinositol phospholipase C activity |
MGI:MGI:4834177 |
ISO: Inferred from Sequence Orthology |
F |
From MGI |
|||
| GO:0004871 |
signal transducer activity |
MGI:MGI:1354194 |
IEA: Inferred from Electronic Annotation |
UniProtKB-KW:KW-0807 |
F |
From MGI |
||
| GO:0004872 |
receptor activity |
MGI:MGI:1354194 |
IEA: Inferred from Electronic Annotation |
UniProtKB-KW:KW-0675 |
F |
From MGI |
||
| GO:0004930 |
G-protein coupled receptor activity |
MGI:MGI:1354194 |
IEA: Inferred from Electronic Annotation |
UniProtKB-KW:KW-0297 |
F |
From MGI |
||
| GO:0004950 |
chemokine receptor activity |
MGI:MGI:4834177 |
ISO: Inferred from Sequence Orthology |
F |
From MGI |
|||
| GO:0005515 |
protein binding |
MGI:MGI:77397 |
IPI: Inferred from Physical Interaction |
F |
From MGI |
|||
| GO:0005886 |
plasma membrane |
MGI:MGI:4834177 |
ISO: Inferred from Sequence Orthology |
C |
From MGI |
|||
| GO:0006816 |
calcium ion transport |
MGI:MGI:4834177 |
ISO: Inferred from Sequence Orthology |
P |
From MGI |
|||
| GO:0006874 |
cellular calcium ion homeostasis |
MGI:MGI:4834177 |
ISO: Inferred from Sequence Orthology |
P |
From MGI |
|||
| GO:0006887 |
exocytosis |
MGI:MGI:4834177 |
ISO: Inferred from Sequence Orthology |
P |
From MGI |
|||
| GO:0006954 |
inflammatory response |
MGI:MGI:893749 |
IMP: Inferred from Mutant Phenotype |
MGI:MGI:1931850 |
P |
From MGI |
||
| GO:0006955 |
immune response |
MGI:MGI:4834177 |
ISO: Inferred from Sequence Orthology |
P |
From MGI |
|||
| GO:0007165 |
signal transduction |
MGI:MGI:1354194 |
IEA: Inferred from Electronic Annotation |
UniProtKB-KW:KW-0807 |
P |
From MGI |
||
| GO:0007186 |
G-protein coupled receptor signaling pathway |
MGI:MGI:1354194 |
IEA: Inferred from Electronic Annotation |
UniProtKB-KW:KW-0297 |
P |
From MGI |
||
| GO:0007186 |
G-protein coupled receptor signaling pathway |
MGI:MGI:4417868 |
ISO: Inferred from Sequence Orthology |
NCBI:NP_065417 |
P |
From MGI |
||
| GO:0007186 |
G-protein coupled receptor signaling pathway |
MGI:MGI:4834177 |
ISO: Inferred from Sequence Orthology |
P |
From MGI |
|||
| GO:0007204 |
elevation of cytosolic calcium ion concentration |
MGI:MGI:4834177 |
ISO: Inferred from Sequence Orthology |
P |
From MGI |
|||
| GO:0007267 |
cell-cell signaling |
MGI:MGI:4834177 |
ISO: Inferred from Sequence Orthology |
P |
From MGI |
|||
| GO:0009897 |
external side of plasma membrane |
MGI:MGI:4417868 |
ISO: Inferred from Sequence Orthology |
NCBI:NP_065417 |
C |
From MGI |
||
| GO:0009897 |
external side of plasma membrane |
MGI:MGI:4834177 |
ISO: Inferred from Sequence Orthology |
C |
From MGI |
|||
| GO:0010629 |
negative regulation of gene expression |
MGI:MGI:4834177 |
ISO: Inferred from Sequence Orthology |
P |
From MGI |
|||
| GO:0016020 |
membrane |
MGI:MGI:1354194 |
IEA: Inferred from Electronic Annotation |
UniProtKB-KW:KW-0472 |
C |
From MGI |
||
| GO:0016021 |
integral to membrane |
MGI:MGI:1354194 |
IEA: Inferred from Electronic Annotation |
UniProtKB-KW:KW-0812 |
C |
From MGI |
||
| GO:0016021 |
integral to membrane |
MGI:MGI:2152098 |
IEA: Inferred from Electronic Annotation |
C |
From MGI |
|||
| GO:0016493 |
C-C chemokine receptor activity |
MGI:MGI:4417868 |
ISO: Inferred from Sequence Orthology |
NCBI:NP_065417 |
F |
From MGI |
||
| GO:0016493 |
C-C chemokine receptor activity |
MGI:MGI:4834177 |
ISO: Inferred from Sequence Orthology |
F |
From MGI |
|||
| GO:0016493 |
C-C chemokine receptor activity |
MGI:MGI:77397 |
IDA: Inferred from Direct Assay |
F |
From MGI |
|||
| GO:0019957 |
C-C chemokine binding |
MGI:MGI:4417868 |
ISO: Inferred from Sequence Orthology |
NCBI:NP_065417 |
F |
From MGI |
||
| GO:0019957 |
C-C chemokine binding |
MGI:MGI:4834177 |
ISO: Inferred from Sequence Orthology |
F |
From MGI |
|||
| GO:0030099 |
myeloid cell differentiation |
MGI:MGI:893749 |
IMP: Inferred from Mutant Phenotype |
MGI:MGI:1931850 |
P |
From MGI |
||
| GO:0030502 |
negative regulation of bone mineralization |
MGI:MGI:4834177 |
ISO: Inferred from Sequence Orthology |
P |
From MGI |
|||
| GO:0030595 |
leukocyte chemotaxis |
MGI:MGI:77397 |
IDA: Inferred from Direct Assay |
P |
From MGI |
|||
| GO:0030595 |
leukocyte chemotaxis |
MGI:MGI:893749 |
IMP: Inferred from Mutant Phenotype |
MGI:MGI:1931850 |
P |
From MGI |
||
| GO:0031620 |
regulation of fever generation |
MGI:MGI:4417868 |
ISO: Inferred from Sequence Orthology |
NCBI:NP_065417 |
P |
From MGI |
||
| GO:0032496 |
response to lipopolysaccharide |
MGI:MGI:4417868 |
ISO: Inferred from Sequence Orthology |
NCBI:NP_065417 |
P |
From MGI |
||
| GO:0035717 |
chemokine (C-C motif) ligand 7 binding |
MGI:MGI:4834177 |
ISO: Inferred from Sequence Orthology |
F |
From MGI |
|||
| GO:0043025 |
neuronal cell body |
MGI:MGI:4417868 |
ISO: Inferred from Sequence Orthology |
NCBI:NP_065417 |
C |
From MGI |
||
| GO:0045672 |
positive regulation of osteoclast differentiation |
MGI:MGI:4834177 |
ISO: Inferred from Sequence Orthology |
P |
From MGI |
|||
| GO:0045824 |
negative regulation of innate immune response |
MGI:MGI:4943412 |
IMP: Inferred from Mutant Phenotype |
P |
From MGI |
|||
| GO:0051928 |
positive regulation of calcium ion transport |
MGI:MGI:4834177 |
ISO: Inferred from Sequence Orthology |
P |
From MGI |
|||
| GO:0070098 |
chemokine-mediated signaling pathway |
MGI:MGI:4834177 |
ISO: Inferred from Sequence Orthology |
P |
From MGI |
|||
| GO:0070374 |
positive regulation of ERK1 and ERK2 cascade |
MGI:MGI:4834177 |
ISO: Inferred from Sequence Orthology |
P |
From MGI |
|||
| GO:0071791 |
chemokine (C-C motif) ligand 5 binding |
MGI:MGI:4834177 |
ISO: Inferred from Sequence Orthology |
F |
From MGI |
|||
| GO:0090026 |
positive regulation of monocyte chemotaxis |
MGI:MGI:4834177 |
ISO: Inferred from Sequence Orthology |
P |
From MGI |
| ||
| edit table |
Notes
References
See Help:References for how to manage references in GONUTS.
- ↑ 1.0 1.1 1.2 Post TW et al. (1995) Molecular characterization of two murine eosinophil beta chemokine receptors. J Immunol 155: 5299-305 PubMed GONUTS page
- ↑ 2.0 2.1 2.2 Gao JL et al. (1997) Impaired host defense, hematopoiesis, granulomatous inflammation and type 1-type 2 cytokine balance in mice lacking CC chemokine receptor 1. J Exp Med 185: 1959-68 PubMed GONUTS page
- ↑ Ness TL et al. (2004) CCR1 and CC chemokine ligand 5 interactions exacerbate innate immune responses during sepsis. J Immunol 173: 6938-48 PubMed GONUTS page
