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MGI:Cbx5
Contents |
| Species (Taxon ID) | Mus musculus (house mouse) (taxon:10090) | |
| Gene Name(s) | Cbx5 ( synonyms: heterochromatin protein 1 alpha, HP1, HP1a ) | |
| Protein Name(s) | chromobox homolog 5 (Drosophila HP1a), | |
| External Links | ||
| MGI | MGI:109372 | |
Annotations
| Qualifier | GO ID | GO term name | Reference | Evidence Code | with/from | Aspect | Notes | Status |
|---|---|---|---|---|---|---|---|---|
| GO:0000118 |
histone deacetylase complex |
MGI:MGI:4359370 |
IDA: Inferred from Direct Assay |
C |
From MGI |
|||
| GO:0000775 |
chromosome, centromeric region |
MGI:MGI:1354194 |
IEA: Inferred from Electronic Annotation |
UniProtKB-KW:KW-0137 |
C |
From MGI |
||
| GO:0000776 |
kinetochore |
MGI:MGI:2682084 |
IDA: Inferred from Direct Assay |
C |
From MGI |
|||
| GO:0000792 |
heterochromatin |
MGI:MGI:3582110 |
IDA: Inferred from Direct Assay |
C |
From MGI |
|||
| GO:0003682 |
chromatin binding |
MGI:MGI:1339222 |
IDA: Inferred from Direct Assay |
F |
From MGI |
|||
| GO:0005515 |
protein binding |
MGI:MGI:1347736 |
IPI: Inferred from Physical Interaction |
F |
From MGI |
|||
| GO:0005515 |
protein binding |
MGI:MGI:3512848 |
IPI: Inferred from Physical Interaction |
F |
From MGI |
|||
| GO:0005515 |
protein binding |
MGI:MGI:3701370 |
IPI: Inferred from Physical Interaction |
F |
From MGI |
|||
| GO:0005515 |
protein binding |
MGI:MGI:84614 |
IPI: Inferred from Physical Interaction |
F |
From MGI |
|||
| GO:0005634 |
nucleus |
MGI:MGI:1339222 |
IDA: Inferred from Direct Assay |
C |
From MGI |
|||
| GO:0005634 |
nucleus |
MGI:MGI:3707931 |
IDA: Inferred from Direct Assay |
C |
From MGI |
|||
| GO:0005634 |
nucleus |
MGI:MGI:4834177 |
ISO: Inferred from Sequence Orthology |
C |
From MGI |
|||
| GO:0005694 |
chromosome |
MGI:MGI:1354194 |
IEA: Inferred from Electronic Annotation |
UniProtKB-KW:KW-0158 |
C |
From MGI |
||
| GO:0005720 |
nuclear heterochromatin |
MGI:MGI:1339222 |
IDA: Inferred from Direct Assay |
C |
From MGI |
|||
| GO:0005720 |
nuclear heterochromatin |
MGI:MGI:3028406 |
IDA: Inferred from Direct Assay |
C |
From MGI |
|||
| GO:0005720 |
nuclear heterochromatin |
MGI:MGI:3044521 |
IDA: Inferred from Direct Assay |
C |
From MGI |
|||
| GO:0005730 |
nucleolus |
MGI:MGI:1339222 |
IDA: Inferred from Direct Assay |
C |
From MGI |
|||
| GO:0005730 |
nucleolus |
MGI:MGI:4834177 |
ISO: Inferred from Sequence Orthology |
C |
From MGI |
|||
| GO:0005737 |
cytoplasm |
MGI:MGI:4834177 |
ISO: Inferred from Sequence Orthology |
C |
From MGI |
|||
| GO:0010369 |
chromocenter |
MGI:MGI:3707931 |
IDA: Inferred from Direct Assay |
C |
From MGI |
|||
| GO:0017053 |
transcriptional repressor complex |
MGI:MGI:4359370 |
IDA: Inferred from Direct Assay |
C |
From MGI |
|||
| GO:0019899 |
enzyme binding |
MGI:MGI:4834177 |
ISO: Inferred from Sequence Orthology |
F |
From MGI |
|||
| GO:0030674 |
protein binding, bridging |
MGI:MGI:4359370 |
IPI: Inferred from Physical Interaction |
F |
From MGI |
|||
| GO:0035064 |
methylated histone residue binding |
MGI:MGI:4834177 |
ISO: Inferred from Sequence Orthology |
F |
From MGI |
|||
| GO:0035097 |
histone methyltransferase complex |
MGI:MGI:4359370 |
IDA: Inferred from Direct Assay |
C |
From MGI |
|||
| GO:0042826 |
histone deacetylase binding |
MGI:MGI:4359370 |
IPI: Inferred from Physical Interaction |
F |
From MGI |
|||
| GO:0045892 |
negative regulation of transcription, DNA-dependent |
MGI:MGI:1347736 |
IDA: Inferred from Direct Assay |
P |
From MGI |
|||
| GO:0045892 |
negative regulation of transcription, DNA-dependent |
MGI:MGI:4834177 |
ISO: Inferred from Sequence Orthology |
P |
From MGI |
|||
| GO:0070491 |
repressing transcription factor binding |
MGI:MGI:4359370 |
IPI: Inferred from Physical Interaction |
F |
From MGI |
| ||
| edit table |
Notes
References
See Help:References for how to manage references in GONUTS.
- ↑ 1.0 1.1 1.2 1.3 1.4 1.5 Zhang CL et al. (2002) Association of class II histone deacetylases with heterochromatin protein 1: potential role for histone methylation in control of muscle differentiation. Mol Cell Biol 22: 7302-12 PubMed GONUTS page
- ↑ Craig JM et al. (2003) Analysis of mammalian proteins involved in chromatin modification reveals new metaphase centromeric proteins and distinct chromosomal distribution patterns. Hum Mol Genet 12: 3109-21 PubMed GONUTS page
- ↑ Dannenberg JH et al. (2005) mSin3A corepressor regulates diverse transcriptional networks governing normal and neoplastic growth and survival. Genes Dev 19: 1581-95 PubMed GONUTS page
- ↑ 4.0 4.1 4.2 4.3 Remboutsika E et al. (1999) The putative nuclear receptor mediator TIF1alpha is tightly associated with euchromatin. J Cell Sci 112 ( Pt 11): 1671-83 PubMed GONUTS page
- ↑ 5.0 5.1 Nielsen AL et al. (1999) Interaction with members of the heterochromatin protein 1 (HP1) family and histone deacetylation are differentially involved in transcriptional silencing by members of the TIF1 family. EMBO J 18: 6385-95 PubMed GONUTS page
- ↑ Khetchoumian K et al. (2004) TIF1delta, a novel HP1-interacting member of the transcriptional intermediary factor 1 (TIF1) family expressed by elongating spermatids. J Biol Chem 279: 48329-41 PubMed GONUTS page
- ↑ Mandel S et al. (2007) Activity-dependent neuroprotective protein (ADNP) differentially interacts with chromatin to regulate genes essential for embryogenesis. Dev Biol 303: 814-24 PubMed GONUTS page
- ↑ Le Douarin B et al. (1996) A possible involvement of TIF1 alpha and TIF1 beta in the epigenetic control of transcription by nuclear receptors. EMBO J 15: 6701-15 PubMed GONUTS page
- ↑ 9.0 9.1 Naetar N et al. (2007) LAP2alpha-binding protein LINT-25 is a novel chromatin-associated protein involved in cell cycle exit. J Cell Sci 120: 737-47 PubMed GONUTS page
- ↑ Asano Y et al. (2004) Lamr1 functional retroposon causes right ventricular dysplasia in mice. Nat Genet 36: 123-30 PubMed GONUTS page
- ↑ Alonso MB et al. (2004) Identification and characterization of ZFP-57, a novel zinc finger transcription factor in the mammalian peripheral nervous system. J Biol Chem 279: 25653-64 PubMed GONUTS page
