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MGI:Cbfb
Contents |
| Species (Taxon ID) | Mus musculus (house mouse) (taxon:10090) | |
| Gene Name(s) | Cbfb ( synonyms: PEA2, Pebp2, PEBP2b, Pebpb2 ) | |
| Protein Name(s) | core binding factor beta, | |
| External Links | ||
| MGI | MGI:99851 | |
Annotations
| Qualifier | GO ID | GO term name | Reference | Evidence Code | with/from | Aspect | Notes | Status |
|---|---|---|---|---|---|---|---|---|
| GO:0001503 |
ossification |
MGI:MGI:2446761 |
IMP: Inferred from Mutant Phenotype |
MGI:MGI:2447293 |
P |
From MGI |
||
| GO:0001503 |
ossification |
MGI:MGI:2446762 |
IMP: Inferred from Mutant Phenotype |
MGI:MGI:1934195 |
P |
From MGI |
||
| GO:0001649 |
osteoblast differentiation |
MGI:MGI:2446761 |
IMP: Inferred from Mutant Phenotype |
MGI:MGI:2447293 |
P |
From MGI |
||
| GO:0003677 |
DNA binding |
MGI:MGI:4417868 |
ISO: Inferred from Sequence Orthology |
NCBI:NP_001013209 |
F |
From MGI |
||
| GO:0003713 |
transcription coactivator activity |
MGI:MGI:2152098 |
IEA: Inferred from Electronic Annotation |
F |
From MGI |
|||
| GO:0005515 |
protein binding |
MGI:MGI:2136064 |
IPI: Inferred from Physical Interaction |
F |
From MGI |
|||
| GO:0005634 |
nucleus |
MGI:MGI:2446761 |
IDA: Inferred from Direct Assay |
C |
From MGI |
|||
| GO:0030098 |
lymphocyte differentiation |
MGI:MGI:2446762 |
IMP: Inferred from Mutant Phenotype |
MGI:MGI:1934195 |
P |
From MGI |
||
| GO:0030099 |
myeloid cell differentiation |
MGI:MGI:2446762 |
IMP: Inferred from Mutant Phenotype |
MGI:MGI:1934195 |
P |
From MGI |
||
| GO:0045944 |
positive regulation of transcription from RNA polymerase II promoter |
MGI:MGI:2446761 |
IDA: Inferred from Direct Assay |
P |
From MGI |
|||
| GO:0048469 |
cell maturation |
MGI:MGI:2446761 |
IMP: Inferred from Mutant Phenotype |
MGI:MGI:2447293 |
P |
From MGI |
||
| GO:0060216 |
definitive hemopoiesis |
MGI:MGI:892682 |
IMP: Inferred from Mutant Phenotype |
MGI:MGI:1933624 |
P |
From MGI |
||
| GO:2001141 |
regulation of RNA biosynthetic process |
MGI:MGI:2152098 |
IEA: Inferred from Electronic Annotation |
P |
From MGI |
| ||
| edit table |
Notes
References
See Help:References for how to manage references in GONUTS.
- ↑ 1.0 1.1 1.2 1.3 1.4 Kundu M et al. (2002) Cbfbeta interacts with Runx2 and has a critical role in bone development. Nat Genet 32: 639-44 PubMed GONUTS page
- ↑ 2.0 2.1 2.2 Miller J et al. (2002) The core-binding factor beta subunit is required for bone formation and hematopoietic maturation. Nat Genet 32: 645-9 PubMed GONUTS page
- ↑ Sakuma T et al. (2001) Cloning and expression pattern of a novel PEBP2 beta-binding protein (charged amino acid rich leucine zipper-1[Crl-1]) in the mouse. Mech Dev 104: 151-4 PubMed GONUTS page
- ↑ Niki M et al. (1997) Hematopoiesis in the fetal liver is impaired by targeted mutagenesis of a gene encoding a non-DNA binding subunit of the transcription factor, polyomavirus enhancer binding protein 2/core binding factor. Proc Natl Acad Sci U S A 94: 5697-702 PubMed GONUTS page
