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MGI:Cat
Contents |
| Species (Taxon ID) | Mus musculus (house mouse) (taxon:10090) | |
| Gene Name(s) | Cat ( synonyms: Cas-1, Cas1, Cs-1 ) | |
| Protein Name(s) | catalase, | |
| External Links | ||
| MGI | MGI:88271 | |
Annotations
| Qualifier | GO ID | GO term name | Reference | Evidence Code | with/from | Aspect | Notes | Status |
|---|---|---|---|---|---|---|---|---|
| GO:0000302 |
response to reactive oxygen species |
MGI:MGI:4417868 |
ISO: Inferred from Sequence Orthology |
P |
From MGI |
|||
| GO:0000302 |
response to reactive oxygen species |
MGI:MGI:4834177 |
ISO: Inferred from Sequence Orthology |
P |
From MGI |
|||
| GO:0001666 |
response to hypoxia |
MGI:MGI:4417868 |
ISO: Inferred from Sequence Orthology |
P |
From MGI |
|||
| GO:0004046 |
aminoacylase activity |
MGI:MGI:3050704 |
IMP: Inferred from Mutant Phenotype |
MGI:MGI:3051232 |
F |
From MGI |
||
| GO:0004096 |
catalase activity |
MGI:MGI:1203408 |
IDA: Inferred from Direct Assay |
F |
From MGI |
|||
| GO:0004096 |
catalase activity |
MGI:MGI:1352605 |
IDA: Inferred from Direct Assay |
F |
From MGI |
|||
| GO:0004096 |
catalase activity |
MGI:MGI:2449252 |
IDA: Inferred from Direct Assay |
F |
From MGI |
|||
| GO:0004096 |
catalase activity |
MGI:MGI:2655950 |
IDA: Inferred from Direct Assay |
F |
From MGI |
|||
| GO:0004096 |
catalase activity |
MGI:MGI:3522379 |
IDA: Inferred from Direct Assay |
F |
From MGI |
|||
| GO:0004096 |
catalase activity |
MGI:MGI:3698896 |
IDA: Inferred from Direct Assay |
F |
From MGI |
|||
| GO:0004096 |
catalase activity |
MGI:MGI:4417868 |
ISO: Inferred from Sequence Orthology |
F |
From MGI |
|||
| GO:0004096 |
catalase activity |
MGI:MGI:4834177 |
ISO: Inferred from Sequence Orthology |
F |
From MGI |
|||
| GO:0004096 |
catalase activity |
MGI:MGI:53494 |
IMP: Inferred from Mutant Phenotype |
MGI:MGI:3053604 |
F |
From MGI |
||
| GO:0004096 |
catalase activity |
MGI:MGI:53581 |
IMP: Inferred from Mutant Phenotype |
MGI:MGI:3053604 |
F |
From MGI |
||
| GO:0004096 |
catalase activity |
MGI:MGI:54448 |
IMP: Inferred from Mutant Phenotype |
MGI:MGI:3053604 |
F |
From MGI |
||
| GO:0004601 |
peroxidase activity |
MGI:MGI:1354194 |
IEA: Inferred from Electronic Annotation |
UniProtKB-KW:KW-0575 |
F |
From MGI |
||
| GO:0005739 |
mitochondrion |
MGI:MGI:2682130 |
IDA: Inferred from Direct Assay |
C |
From MGI |
|||
| GO:0005758 |
mitochondrial intermembrane space |
MGI:MGI:4417868 |
ISO: Inferred from Sequence Orthology |
C |
From MGI |
|||
| GO:0005764 |
lysosome |
MGI:MGI:4417868 |
ISO: Inferred from Sequence Orthology |
C |
From MGI |
|||
| GO:0005777 |
peroxisome |
MGI:MGI:1933722 |
IDA: Inferred from Direct Assay |
C |
From MGI |
|||
| GO:0005777 |
peroxisome |
MGI:MGI:2158861 |
IDA: Inferred from Direct Assay |
C |
From MGI |
|||
| GO:0005777 |
peroxisome |
MGI:MGI:3698896 |
IDA: Inferred from Direct Assay |
C |
From MGI |
|||
| GO:0005777 |
peroxisome |
MGI:MGI:4417868 |
ISO: Inferred from Sequence Orthology |
C |
From MGI |
|||
| GO:0005777 |
peroxisome |
MGI:MGI:4834177 |
ISO: Inferred from Sequence Orthology |
C |
From MGI |
|||
| GO:0005778 |
peroxisomal membrane |
MGI:MGI:3052413 |
IDA: Inferred from Direct Assay |
C |
From MGI |
|||
| GO:0005783 |
endoplasmic reticulum |
MGI:MGI:4417868 |
ISO: Inferred from Sequence Orthology |
C |
From MGI |
|||
| GO:0005794 |
Golgi apparatus |
MGI:MGI:4417868 |
ISO: Inferred from Sequence Orthology |
C |
From MGI |
|||
| GO:0005829 |
cytosol |
MGI:MGI:4417868 |
ISO: Inferred from Sequence Orthology |
C |
From MGI |
|||
| GO:0005886 |
plasma membrane |
MGI:MGI:4417868 |
ISO: Inferred from Sequence Orthology |
C |
From MGI |
|||
| GO:0006641 |
triglyceride metabolic process |
MGI:MGI:53683 |
IMP: Inferred from Mutant Phenotype |
MGI:MGI:3053604 |
P |
From MGI |
||
| GO:0006979 |
response to oxidative stress |
MGI:MGI:3050704 |
IMP: Inferred from Mutant Phenotype |
MGI:MGI:3051232 |
P |
From MGI |
||
| GO:0006979 |
response to oxidative stress |
MGI:MGI:3698896 |
IDA: Inferred from Direct Assay |
P |
From MGI |
|||
| GO:0006979 |
response to oxidative stress |
MGI:MGI:4417868 |
ISO: Inferred from Sequence Orthology |
P |
From MGI |
|||
| GO:0008203 |
cholesterol metabolic process |
MGI:MGI:53683 |
IMP: Inferred from Mutant Phenotype |
MGI:MGI:3053604 |
P |
From MGI |
||
| GO:0009060 |
aerobic respiration |
MGI:MGI:3050704 |
IMP: Inferred from Mutant Phenotype |
MGI:MGI:3051232 |
P |
From MGI |
||
| GO:0009650 |
UV protection |
MGI:MGI:4834177 |
ISO: Inferred from Sequence Orthology |
P |
From MGI |
|||
| GO:0014068 |
positive regulation of phosphatidylinositol 3-kinase cascade |
MGI:MGI:3037350 |
IDA: Inferred from Direct Assay |
P |
From MGI |
|||
| GO:0016491 |
oxidoreductase activity |
MGI:MGI:1354194 |
IEA: Inferred from Electronic Annotation |
UniProtKB-KW:KW-0560 |
F |
From MGI |
||
| GO:0016684 |
oxidoreductase activity, acting on peroxide as acceptor |
MGI:MGI:2157179 |
IDA: Inferred from Direct Assay |
F |
From MGI |
|||
| GO:0020027 |
hemoglobin metabolic process |
MGI:MGI:66714 |
IMP: Inferred from Mutant Phenotype |
MGI:MGI:3053604 |
P |
From MGI |
||
| GO:0020037 |
heme binding |
MGI:MGI:4834177 |
ISO: Inferred from Sequence Orthology |
F |
From MGI |
|||
| GO:0032088 |
negative regulation of NF-kappaB transcription factor activity |
MGI:MGI:1203408 |
IDA: Inferred from Direct Assay |
P |
From MGI |
|||
| GO:0042744 |
hydrogen peroxide catabolic process |
MGI:MGI:1203408 |
IDA: Inferred from Direct Assay |
P |
From MGI |
|||
| GO:0042744 |
hydrogen peroxide catabolic process |
MGI:MGI:1352605 |
IDA: Inferred from Direct Assay |
P |
From MGI |
|||
| GO:0042744 |
hydrogen peroxide catabolic process |
MGI:MGI:3050704 |
IMP: Inferred from Mutant Phenotype |
MGI:MGI:3051232 |
P |
From MGI |
||
| GO:0042744 |
hydrogen peroxide catabolic process |
MGI:MGI:3698896 |
IDA: Inferred from Direct Assay |
P |
From MGI |
|||
| GO:0042744 |
hydrogen peroxide catabolic process |
MGI:MGI:4417868 |
ISO: Inferred from Sequence Orthology |
P |
From MGI |
|||
| GO:0042744 |
hydrogen peroxide catabolic process |
MGI:MGI:4834177 |
ISO: Inferred from Sequence Orthology |
P |
From MGI |
|||
| GO:0042744 |
hydrogen peroxide catabolic process |
MGI:MGI:54448 |
IMP: Inferred from Mutant Phenotype |
MGI:MGI:3053604 |
P |
From MGI |
||
| GO:0042803 |
protein homodimerization activity |
MGI:MGI:4834177 |
ISO: Inferred from Sequence Orthology |
F |
From MGI |
|||
| GO:0043066 |
negative regulation of apoptotic process |
MGI:MGI:4417868 |
ISO: Inferred from Sequence Orthology |
P |
From MGI |
|||
| GO:0043066 |
negative regulation of apoptotic process |
MGI:MGI:4834177 |
ISO: Inferred from Sequence Orthology |
P |
From MGI |
|||
| GO:0046872 |
metal ion binding |
MGI:MGI:1354194 |
IEA: Inferred from Electronic Annotation |
UniProtKB-KW:KW-0479 |
F |
From MGI |
||
| GO:0050661 |
NADP binding |
MGI:MGI:4834177 |
ISO: Inferred from Sequence Orthology |
F |
From MGI |
|||
| GO:0051092 |
positive regulation of NF-kappaB transcription factor activity |
MGI:MGI:3037350 |
IDA: Inferred from Direct Assay |
P |
From MGI |
|||
| GO:0051262 |
protein tetramerization |
MGI:MGI:4834177 |
ISO: Inferred from Sequence Orthology |
P |
From MGI |
|||
| GO:0051781 |
positive regulation of cell division |
MGI:MGI:1354194 |
IEA: Inferred from Electronic Annotation |
UniProtKB-KW:KW-0497 |
P |
From MGI |
| |
| edit table |
Notes
References
See Help:References for how to manage references in GONUTS.
- ↑ 1.0 1.1 1.2 1.3 Ho YS et al. (2004) Mice lacking catalase develop normally but show differential sensitivity to oxidant tissue injury. J Biol Chem 279: 32804-12 PubMed GONUTS page
- ↑ 2.0 2.1 2.2 Nilakantan V et al. (1998) Liver-specific catalase expression in transgenic mice inhibits NF-kappaB activation and DNA synthesis induced by the peroxisome proliferator ciprofibrate. Carcinogenesis 19: 631-7 PubMed GONUTS page
- ↑ 3.0 3.1 Muppala V et al. (2000) The role of HNF-1alpha in controlling hepatic catalase activity. Mol Pharmacol 57: 93-100 PubMed GONUTS page
- ↑ Felix K et al. (2003) Redox imbalance and mutagenesis in spleens of mice harboring a hypomorphic allele of Gpdx(a) encoding glucose 6-phosphate dehydrogenase. Free Radic Biol Med 34: 226-32 PubMed GONUTS page
- ↑ Khan JY & Black SM (2003) Developmental changes in murine brain antioxidant enzymes. Pediatr Res 54: 77-82 PubMed GONUTS page
- ↑ Muller FL et al. (2004) Complex III releases superoxide to both sides of the inner mitochondrial membrane. J Biol Chem 279: 49064-73 PubMed GONUTS page
- ↑ 7.0 7.1 7.2 7.3 Bonini MG et al. (2007) Immunolocalization of hypochlorite-induced, catalase-bound free radical formation in mouse hepatocytes. Free Radic Biol Med 42: 530-40 PubMed GONUTS page
- ↑ Feinstein RN et al. (1966) Acatalasemic and hypocatalasemic mouse mutants. Genetics 53: 923-33 PubMed GONUTS page
- ↑ Feinstein RN et al. (1968) Blood catalsase polymorphism: some immunological aspects. Science 159: 638-40 PubMed GONUTS page
- ↑ 10.0 10.1 Feinstein RN et al. (1978) Carcinogenic and antitumor effects of aminotriazole on acatalasemic and normal catalase mice. J Natl Cancer Inst 60: 1113-6 PubMed GONUTS page
- ↑ Mootha VK et al. (2003) Integrated analysis of protein composition, tissue diversity, and gene regulation in mouse mitochondria. Cell 115: 629-40 PubMed GONUTS page
- ↑ Grabenbauer M et al. (2001) Detection of peroxisomal proteins and their mRNAs in serial sections of fetal and newborn mouse organs. J Histochem Cytochem 49: 155-64 PubMed GONUTS page
- ↑ Björkman J et al. (2002) Pex13, the mouse ortholog of the human peroxisome biogenesis disorder PEX13 gene: gene structure, tissue expression, and localization of the protein to peroxisomes. Genomics 79: 162-8 PubMed GONUTS page
- ↑ Brites P et al. (2003) Impaired neuronal migration and endochondral ossification in Pex7 knockout mice: a model for rhizomelic chondrodysplasia punctata. Hum Mol Genet 12: 2255-67 PubMed GONUTS page
- ↑ 15.0 15.1 Goldfischer S et al. (1971) Hypolipidemia in a mutant strain of "acatalasemic" mice. Science 173: 65-6 PubMed GONUTS page
- ↑ 16.0 16.1 Jang BC et al. (2004) Induction of cyclooxygenase-2 in macrophages by catalase: role of NF-kappaB and PI3K signaling pathways. Biochem Biophys Res Commun 316: 398-406 PubMed GONUTS page
- ↑ Hogenboom S et al. (2002) Absence of functional peroxisomes does not lead to deficiency of enzymes involved in cholesterol biosynthesis. J Lipid Res 43: 90-8 PubMed GONUTS page
- ↑ Zhen LX et al. (1993) Inhibitory effect of alpha-tocopherol on methemoglobin formation by nitric oxide in normal and acatalasemic mouse hemolysates. Physiol Chem Phys Med NMR 25: 253-60 PubMed GONUTS page
