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MGI:Casr

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Contents

Species (Taxon ID) Mus musculus (house mouse) (taxon:10090)
Gene Name(s) Casr ( synonyms: CaR, cation sensing receptor, Gprc2a )
Protein Name(s) calcium-sensing receptor,
External Links
MGI MGI:1351351

Annotations

Qualifier GO ID GO term name Reference Evidence Code with/from Aspect Notes Status
GO:0001503

ossification

MGI:MGI:4417868

ISO: Inferred from Sequence Orthology

UniProtKB:P48442

P

From MGI

GO:0004871

signal transducer activity

MGI:MGI:1354194

IEA: Inferred from Electronic Annotation

UniProtKB-KW:KW-0807

F

From MGI

GO:0004872

receptor activity

MGI:MGI:1354194

IEA: Inferred from Electronic Annotation

UniProtKB-KW:KW-0675

F

From MGI

GO:0004930

G-protein coupled receptor activity

MGI:MGI:4417868

ISO: Inferred from Sequence Orthology

UniProtKB:P48442

F

From MGI

GO:0005513

detection of calcium ion

MGI:MGI:2152098

IEA: Inferred from Electronic Annotation

InterPro:IPR015531

P

From MGI

GO:0005622

intracellular

MGI:MGI:2152098

IEA: Inferred from Electronic Annotation

InterPro:IPR015531

C

From MGI

GO:0005622

intracellular

MGI:MGI:4417868

ISO: Inferred from Sequence Orthology

UniProtKB:P48442

C

From MGI

GO:0005886

plasma membrane

MGI:MGI:1354194

IEA: Inferred from Electronic Annotation

UniProtKB-KW:KW-1003

C

From MGI

GO:0006816

calcium ion transport

MGI:MGI:4417868

ISO: Inferred from Sequence Orthology

UniProtKB:P48442

P

From MGI

GO:0006874

cellular calcium ion homeostasis

MGI:MGI:4417868

ISO: Inferred from Sequence Orthology

UniProtKB:P48442

P

From MGI

GO:0007165

signal transduction

MGI:MGI:1354194

IEA: Inferred from Electronic Annotation

UniProtKB-KW:KW-0807

P

From MGI

GO:0007186

G-protein coupled receptor signaling pathway

MGI:MGI:4417868

ISO: Inferred from Sequence Orthology

UniProtKB:P48442

P

From MGI

GO:0007254

JNK cascade

MGI:MGI:4417868

ISO: Inferred from Sequence Orthology

UniProtKB:P48442

P

From MGI

GO:0008284

positive regulation of cell proliferation

MGI:MGI:4417868

ISO: Inferred from Sequence Orthology

UniProtKB:P48442

P

From MGI

GO:0010628

positive regulation of gene expression

MGI:MGI:3836532
PMID:18794335[1]

IDA: Inferred from Direct Assay

P

From MGI

GO:0016020

membrane

MGI:MGI:1354194

IEA: Inferred from Electronic Annotation

UniProtKB-KW:KW-0472

C

From MGI

GO:0016021

integral to membrane

MGI:MGI:1354194

IEA: Inferred from Electronic Annotation

UniProtKB-KW:KW-0812

C

From MGI

GO:0016021

integral to membrane

MGI:MGI:2152098

IEA: Inferred from Electronic Annotation

InterPro:IPR000337
InterPro:IPR017978
InterPro:IPR015531
InterPro:IPR017979

C

From MGI

GO:0019722

calcium-mediated signaling

MGI:MGI:2152098

IEA: Inferred from Electronic Annotation

InterPro:IPR015531

P

From MGI

GO:0032781

positive regulation of ATPase activity

MGI:MGI:3773002
PMID:17823248[2]

IDA: Inferred from Direct Assay

P

From MGI

GO:0032781

positive regulation of ATPase activity

MGI:MGI:3773002
PMID:17823248[2]

IMP: Inferred from Mutant Phenotype

P

From MGI

GO:0042311

vasodilation

MGI:MGI:4417868

ISO: Inferred from Sequence Orthology

UniProtKB:P48442

P

From MGI

GO:0043679

axon terminus

MGI:MGI:4417868

ISO: Inferred from Sequence Orthology

UniProtKB:P48442

C

From MGI

GO:0051924

regulation of calcium ion transport

MGI:MGI:3773002
PMID:17823248[2]

IDA: Inferred from Direct Assay

P

From MGI

GO:0070509

calcium ion import

MGI:MGI:4834177

ISO: Inferred from Sequence Orthology

UniProtKB:P41180

P

From MGI


Notes

References

See Help:References for how to manage references in GONUTS.
  1. van Waterschoot RA et al. (2009) Intestinal cytochrome P450 3A plays an important role in the regulation of detoxifying systems in the liver. FASEB J 23: 224-31 PubMed GONUTS page
  2. 2.0 2.1 2.2 VanHouten JN et al. (2007) The calcium-sensing receptor regulates plasma membrane calcium adenosine triphosphatase isoform 2 activity in mammary epithelial cells: a mechanism for calcium-regulated calcium transport into milk. Endocrinology 148: 5943-54 PubMed GONUTS page
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