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MGI:Cartpt

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Contents

Species (Taxon ID) Mus musculus (house mouse) (taxon:10090)
Gene Name(s) Cartpt ( synonyms: Cart )
Protein Name(s) CART prepropeptide,
External Links
MGI MGI:1351330

Annotations

Qualifier GO ID GO term name Reference Evidence Code with/from Aspect Notes Status
GO:0000186

activation of MAPKK activity

MGI:MGI:3696614
PMID:15908120[1]

IDA: Inferred from Direct Assay

P

From MGI

GO:0000186

activation of MAPKK activity

MGI:MGI:4417868

ISO: Inferred from Sequence Orthology

UniProtKB:P49192

P

From MGI

GO:0001678

cellular glucose homeostasis

MGI:MGI:4834177

ISO: Inferred from Sequence Orthology

UniProtKB:Q16568

P

From MGI

GO:0005184

neuropeptide hormone activity

MGI:MGI:1350841
PMID:10612705[2]

TAS: Traceable Author Statement

F

From MGI

GO:0005576

extracellular region

MGI:MGI:1354194

IEA: Inferred from Electronic Annotation

UniProtKB-KW:KW-0964

C

From MGI

GO:0005615

extracellular space

MGI:MGI:1203479
PMID:9590691[3]

IDA: Inferred from Direct Assay

C

From MGI

GO:0005615

extracellular space

MGI:MGI:4417868

ISO: Inferred from Sequence Orthology

UniProtKB:P49192

C

From MGI

GO:0005615

extracellular space

MGI:MGI:4834177

ISO: Inferred from Sequence Orthology

UniProtKB:Q16568

C

From MGI

GO:0007186

G-protein coupled receptor signaling pathway

MGI:MGI:3696614
PMID:15908120[1]

IDA: Inferred from Direct Assay

P

From MGI

GO:0007186

G-protein coupled receptor signaling pathway

MGI:MGI:4417868

ISO: Inferred from Sequence Orthology

UniProtKB:P49192

P

From MGI

GO:0007218

neuropeptide signaling pathway

MGI:MGI:1350841
PMID:10612705[2]

TAS: Traceable Author Statement

P

From MGI

GO:0007268

synaptic transmission

MGI:MGI:1354194

IEA: Inferred from Electronic Annotation

UniProtKB-KW:KW-0529

P

From MGI

GO:0008343

adult feeding behavior

MGI:MGI:1203479
PMID:9590691[3]

IDA: Inferred from Direct Assay

P

From MGI

GO:0008343

adult feeding behavior

MGI:MGI:4417868

ISO: Inferred from Sequence Orthology

UniProtKB:P49192

P

From MGI

GO:0009267

cellular response to starvation

MGI:MGI:1203479
PMID:9590691[3]

IDA: Inferred from Direct Assay

P

From MGI

GO:0009267

cellular response to starvation

MGI:MGI:4417868

ISO: Inferred from Sequence Orthology

UniProtKB:P49192

P

From MGI

GO:0030141

secretory granule

MGI:MGI:4834177

ISO: Inferred from Sequence Orthology

UniProtKB:Q16568

C

From MGI

GO:0032099

negative regulation of appetite

MGI:MGI:1203479
PMID:9590691[3]

IMP: Inferred from Mutant Phenotype

P

From MGI

GO:0032099

negative regulation of appetite

MGI:MGI:4417868

ISO: Inferred from Sequence Orthology

UniProtKB:P49192

P

From MGI

GO:0032812

positive regulation of epinephrine secretion

MGI:MGI:4834177

ISO: Inferred from Sequence Orthology

UniProtKB:Q16568

P

From MGI

GO:0032922

circadian regulation of gene expression

MGI:MGI:4417868

ISO: Inferred from Sequence Orthology

UniProtKB:P49192

P

From MGI

GO:0045671

negative regulation of osteoclast differentiation

MGI:MGI:3696590
PMID:16614075[4]

TAS: Traceable Author Statement

P

From MGI

GO:0045777

positive regulation of blood pressure

MGI:MGI:4834177

ISO: Inferred from Sequence Orthology

UniProtKB:Q16568

P

From MGI

GO:0045779

negative regulation of bone resorption

MGI:MGI:3696590
PMID:16614075[4]

IGI: Inferred from Genetic Interaction

UniProtKB:P56450

P

From MGI

GO:0045779

negative regulation of bone resorption

MGI:MGI:4834177

ISO: Inferred from Sequence Orthology

UniProtKB:Q16568

P

From MGI

GO:0046850

regulation of bone remodeling

MGI:MGI:3575849
PMID:15724149[5]

IMP: Inferred from Mutant Phenotype

MGI:MGI:3576858

P

From MGI

GO:0050796

regulation of insulin secretion

MGI:MGI:4417868

ISO: Inferred from Sequence Orthology

UniProtKB:P49192

P

From MGI

GO:0051971

positive regulation of transmission of nerve impulse

MGI:MGI:4834177

ISO: Inferred from Sequence Orthology

UniProtKB:Q16568

P

From MGI

GO:0070093

negative regulation of glucagon secretion

MGI:MGI:4417868

ISO: Inferred from Sequence Orthology

UniProtKB:P49192

P

From MGI

GO:0070253

somatostatin secretion

MGI:MGI:4417868

ISO: Inferred from Sequence Orthology

UniProtKB:P49192

P

From MGI


Notes

References

See Help:References for how to manage references in GONUTS.
  1. 1.0 1.1 Lakatos A et al. (2005) Cocaine- and amphetamine-regulated transcript (CART) peptide activates the extracellular signal-regulated kinase (ERK) pathway in AtT20 cells via putative G-protein coupled receptors. Neurosci Lett 384: 198-202 PubMed GONUTS page
  2. 2.0 2.1 Adams LD et al. (1999) CART: from gene to function. Brain Res 848: 137-40 PubMed GONUTS page
  3. 3.0 3.1 3.2 3.3 Kristensen P et al. (1998) Hypothalamic CART is a new anorectic peptide regulated by leptin. Nature 393: 72-6 PubMed GONUTS page
  4. 4.0 4.1 Ahn JD et al. (2006) Cart overexpression is the only identifiable cause of high bone mass in melanocortin 4 receptor deficiency. Endocrinology 147: 3196-202 PubMed GONUTS page
  5. Elefteriou F et al. (2005) Leptin regulation of bone resorption by the sympathetic nervous system and CART. Nature 434: 514-20 PubMed GONUTS page
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