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MGI:Carm1
Contents |
| Species (Taxon ID) | Mus musculus (house mouse) (taxon:10090) | |
| Gene Name(s) | Carm1 ( synonyms: Prmt4 ) | |
| Protein Name(s) | coactivator-associated arginine methyltransferase 1, | |
| External Links | ||
| MGI | MGI:1913208 | |
Annotations
| Qualifier | GO ID | GO term name | Reference | Evidence Code | with/from | Aspect | Notes | Status |
|---|---|---|---|---|---|---|---|---|
| GO:0003420 |
regulation of growth plate cartilage chondrocyte proliferation |
MGI:MGI:4365886 |
IMP: Inferred from Mutant Phenotype |
MGI:MGI:2663959 |
P |
From MGI |
||
| GO:0003713 |
transcription coactivator activity |
MGI:MGI:1891510 |
IDA: Inferred from Direct Assay |
F |
From MGI |
|||
| GO:0003713 |
transcription coactivator activity |
MGI:MGI:4887324 |
IDA: Inferred from Direct Assay |
F |
From MGI |
|||
| GO:0005515 |
protein binding |
MGI:MGI:1891510 |
IPI: Inferred from Physical Interaction |
F |
From MGI |
|||
| GO:0005515 |
protein binding |
MGI:MGI:4365886 |
IPI: Inferred from Physical Interaction |
F |
From MGI |
|||
| GO:0005515 |
protein binding |
MGI:MGI:4887326 |
IPI: Inferred from Physical Interaction |
F |
From MGI |
|||
| GO:0005634 |
nucleus |
MGI:MGI:4417868 |
ISO: Inferred from Sequence Orthology |
NCBI:NP_001025212 |
C |
From MGI |
||
| GO:0005634 |
nucleus |
MGI:MGI:4834177 |
ISO: Inferred from Sequence Orthology |
C |
From MGI |
|||
| GO:0005634 |
nucleus |
MGI:MGI:4887320 |
IDA: Inferred from Direct Assay |
C |
From MGI |
|||
| GO:0005737 |
cytoplasm |
MGI:MGI:4417868 |
ISO: Inferred from Sequence Orthology |
NCBI:NP_001025212 |
C |
From MGI |
||
| GO:0005737 |
cytoplasm |
MGI:MGI:4834177 |
ISO: Inferred from Sequence Orthology |
C |
From MGI |
|||
| GO:0005829 |
cytosol |
MGI:MGI:4887320 |
IDA: Inferred from Direct Assay |
C |
From MGI |
|||
| GO:0006351 |
transcription, DNA-dependent |
MGI:MGI:1354194 |
IEA: Inferred from Electronic Annotation |
UniProtKB-KW:KW-0804 |
P |
From MGI |
||
| GO:0006355 |
regulation of transcription, DNA-dependent |
MGI:MGI:1891510 |
IDA: Inferred from Direct Assay |
P |
From MGI |
|||
| GO:0006479 |
protein methylation |
MGI:MGI:2152098 |
IEA: Inferred from Electronic Annotation |
P |
From MGI |
|||
| GO:0008168 |
methyltransferase activity |
MGI:MGI:1354194 |
IEA: Inferred from Electronic Annotation |
UniProtKB-KW:KW-0489 |
F |
From MGI |
||
| GO:0008168 |
methyltransferase activity |
MGI:MGI:2152098 |
IEA: Inferred from Electronic Annotation |
F |
From MGI |
|||
| GO:0008276 |
protein methyltransferase activity |
MGI:MGI:1891510 |
IDA: Inferred from Direct Assay |
F |
From MGI |
|||
| GO:0008276 |
protein methyltransferase activity |
MGI:MGI:4365886 |
IDA: Inferred from Direct Assay |
F |
From MGI |
|||
| GO:0008284 |
positive regulation of cell proliferation |
MGI:MGI:4365886 |
IMP: Inferred from Mutant Phenotype |
MGI:MGI:2663959 |
P |
From MGI |
||
| GO:0008284 |
positive regulation of cell proliferation |
MGI:MGI:4417868 |
ISO: Inferred from Sequence Orthology |
NCBI:NP_001025212 |
P |
From MGI |
||
| GO:0008469 |
histone-arginine N-methyltransferase activity |
MGI:MGI:2152096 |
IEA: Inferred from Electronic Annotation |
F |
From MGI |
|||
| GO:0009405 |
pathogenesis |
MGI:MGI:2152098 |
IEA: Inferred from Electronic Annotation |
P |
From MGI |
|||
| GO:0016274 |
protein-arginine N-methyltransferase activity |
MGI:MGI:4887320 |
IDA: Inferred from Direct Assay |
F |
From MGI |
|||
| GO:0016568 |
chromatin modification |
MGI:MGI:1354194 |
IEA: Inferred from Electronic Annotation |
UniProtKB-KW:KW-0156 |
P |
From MGI |
||
| GO:0016571 |
histone methylation |
MGI:MGI:1891510 |
IDA: Inferred from Direct Assay |
P |
From MGI |
|||
| GO:0016571 |
histone methylation |
MGI:MGI:4834177 |
ISO: Inferred from Sequence Orthology |
P |
From MGI |
|||
| GO:0016740 |
transferase activity |
MGI:MGI:1354194 |
IEA: Inferred from Electronic Annotation |
UniProtKB-KW:KW-0808 |
F |
From MGI |
||
| GO:0030374 |
ligand-dependent nuclear receptor transcription coactivator activity |
MGI:MGI:4887320 |
IDA: Inferred from Direct Assay |
F |
From MGI |
|||
| GO:0030518 |
intracellular steroid hormone receptor signaling pathway |
MGI:MGI:3530629 |
IDA: Inferred from Direct Assay |
P |
From MGI |
|||
| GO:0032091 |
negative regulation of protein binding |
MGI:MGI:4365886 |
IDA: Inferred from Direct Assay |
P |
From MGI |
|||
| GO:0032259 |
methylation |
MGI:MGI:1354194 |
IEA: Inferred from Electronic Annotation |
UniProtKB-KW:KW-0489 |
P |
From MGI |
||
| GO:0033146 |
regulation of intracellular estrogen receptor signaling pathway |
MGI:MGI:4887320 |
IDA: Inferred from Direct Assay |
P |
From MGI |
|||
| GO:0034969 |
histone arginine methylation |
MGI:MGI:2152096 |
IEA: Inferred from Electronic Annotation |
P |
From MGI |
|||
| GO:0034969 |
histone arginine methylation |
MGI:MGI:4887326 |
IDA: Inferred from Direct Assay |
P |
From MGI |
|||
| GO:0034970 |
histone H3-R2 methylation |
MGI:MGI:4834177 |
ISO: Inferred from Sequence Orthology |
P |
From MGI |
|||
| GO:0034971 |
histone H3-R17 methylation |
MGI:MGI:4887324 |
IDA: Inferred from Direct Assay |
P |
From MGI |
|||
| GO:0034971 |
histone H3-R17 methylation |
MGI:MGI:5009188 |
IDA: Inferred from Direct Assay |
P |
From MGI |
|||
| GO:0035242 |
protein-arginine omega-N asymmetric methyltransferase activity |
MGI:MGI:5009188 |
IDA: Inferred from Direct Assay |
F |
From MGI |
|||
| GO:0035246 |
peptidyl-arginine N-methylation |
MGI:MGI:2152096 |
IEA: Inferred from Electronic Annotation |
P |
From MGI |
|||
| GO:0035642 |
histone methyltransferase activity (H3-R17 specific) |
MGI:MGI:5009188 |
IDA: Inferred from Direct Assay |
F |
From MGI |
|||
| GO:0042054 |
histone methyltransferase activity |
MGI:MGI:4834177 |
ISO: Inferred from Sequence Orthology |
F |
From MGI |
|||
| GO:0042054 |
histone methyltransferase activity |
MGI:MGI:4887326 |
IDA: Inferred from Direct Assay |
F |
From MGI |
|||
| GO:0042803 |
protein homodimerization activity |
MGI:MGI:4887320 |
IPI: Inferred from Physical Interaction |
F |
From MGI |
|||
| GO:0044212 |
transcription regulatory region DNA binding |
MGI:MGI:4887324 |
IMP: Inferred from Mutant Phenotype |
F |
From MGI |
|||
| GO:0045600 |
positive regulation of fat cell differentiation |
MGI:MGI:4887324 |
IMP: Inferred from Mutant Phenotype |
P |
From MGI |
|||
| GO:0051591 |
response to cAMP |
MGI:MGI:4417868 |
ISO: Inferred from Sequence Orthology |
NCBI:NP_001025212 |
P |
From MGI |
||
| GO:0060350 |
endochondral bone morphogenesis |
MGI:MGI:4365886 |
IMP: Inferred from Mutant Phenotype |
MGI:MGI:2663959 |
P |
From MGI |
||
| GO:0070577 |
histone acetyl-lysine binding |
MGI:MGI:4887326 |
IDA: Inferred from Direct Assay |
F |
From MGI |
| ||
| edit table |
Notes
References
See Help:References for how to manage references in GONUTS.
- ↑ 1.0 1.1 1.2 1.3 1.4 1.5 Ito T et al. (2009) Arginine methyltransferase CARM1/PRMT4 regulates endochondral ossification. BMC Dev Biol 9: 47 PubMed GONUTS page
- ↑ 2.0 2.1 2.2 2.3 2.4 Chen D et al. (1999) Regulation of transcription by a protein methyltransferase. Science 284: 2174-7 PubMed GONUTS page
- ↑ 3.0 3.1 3.2 3.3 Yadav N et al. (2008) CARM1 promotes adipocyte differentiation by coactivating PPARgamma. EMBO Rep 9: 193-8 PubMed GONUTS page
- ↑ 4.0 4.1 4.2 4.3 Yue WW et al. (2007) Insights into histone code syntax from structural and biochemical studies of CARM1 methyltransferase. EMBO J 26: 4402-12 PubMed GONUTS page
- ↑ 5.0 5.1 5.2 5.3 5.4 5.5 Feng Q et al. (2009) Biochemical control of CARM1 enzymatic activity by phosphorylation. J Biol Chem 284: 36167-74 PubMed GONUTS page
- ↑ Kim JH et al. (2003) CoCoA, a nuclear receptor coactivator which acts through an N-terminal activation domain of p160 coactivators. Mol Cell 12: 1537-49 PubMed GONUTS page
- ↑ 7.0 7.1 7.2 Schurter BT et al. (2001) Methylation of histone H3 by coactivator-associated arginine methyltransferase 1. Biochemistry 40: 5747-56 PubMed GONUTS page
