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MGI:Card9

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Contents

Species (Taxon ID) Mus musculus (house mouse) (taxon:10090)
Gene Name(s) Card9 ( synonyms: LOC332579 )
Protein Name(s) caspase recruitment domain family, member 9,
External Links
MGI MGI:2685628

Annotations

Qualifier GO ID GO term name Reference Evidence Code with/from Aspect Notes Status
GO:0005515

protein binding

MGI:MGI:3697751
PMID:17187069[1]

IPI: Inferred from Physical Interaction

UniProtKB:Q8K3Z0

F

From MGI

GO:0005737

cytoplasm

MGI:MGI:4834177

ISO: Inferred from Sequence Orthology

UniProtKB:Q9H257

C

From MGI

GO:0007249

I-kappaB kinase/NF-kappaB cascade

MGI:MGI:4417868

ISO: Inferred from Sequence Orthology

NCBI:NP_071639

P

From MGI

GO:0009620

response to fungus

MGI:MGI:3654747
PMID:16862125[2]

IMP: Inferred from Mutant Phenotype

MGI:MGI:3663486

P

From MGI

GO:0019904

protein domain specific binding

MGI:MGI:4417868

ISO: Inferred from Sequence Orthology

NCBI:NP_071639

F

From MGI

GO:0032494

response to peptidoglycan

MGI:MGI:3697751
PMID:17187069[1]

IMP: Inferred from Mutant Phenotype

MGI:MGI:3698412

P

From MGI

GO:0032495

response to muramyl dipeptide

MGI:MGI:3697751
PMID:17187069[1]

IMP: Inferred from Mutant Phenotype

MGI:MGI:3698412

P

From MGI

GO:0032755

positive regulation of interleukin-6 production

MGI:MGI:3697751
PMID:17187069[1]

IMP: Inferred from Mutant Phenotype

MGI:MGI:3698412

P

From MGI

GO:0032760

positive regulation of tumor necrosis factor production

MGI:MGI:3697751
PMID:17187069[1]

IMP: Inferred from Mutant Phenotype

MGI:MGI:3698412

P

From MGI

GO:0032874

positive regulation of stress-activated MAPK cascade

MGI:MGI:3697751
PMID:17187069[1]

IMP: Inferred from Mutant Phenotype

MGI:MGI:3698412

P

From MGI

GO:0032874

positive regulation of stress-activated MAPK cascade

MGI:MGI:3697751
PMID:17187069[1]

ISA: Inferred from Sequence Alignment

UniProtKB:Q9H257

P

From MGI

GO:0042493

response to drug

MGI:MGI:3697751
PMID:17187069[1]

IMP: Inferred from Mutant Phenotype

MGI:MGI:3698412

P

From MGI

GO:0042534

regulation of tumor necrosis factor biosynthetic process

MGI:MGI:3654747
PMID:16862125[2]

IMP: Inferred from Mutant Phenotype

MGI:MGI:3663486

P

From MGI

GO:0042803

protein homodimerization activity

MGI:MGI:4834177

ISO: Inferred from Sequence Orthology

UniProtKB:Q9H257

F

From MGI

GO:0043330

response to exogenous dsRNA

MGI:MGI:3697751
PMID:17187069[1]

IMP: Inferred from Mutant Phenotype

MGI:MGI:3698412

P

From MGI

GO:0045076

regulation of interleukin-2 biosynthetic process

MGI:MGI:3654747
PMID:16862125[2]

IMP: Inferred from Mutant Phenotype

MGI:MGI:3663486

P

From MGI

GO:0045089

positive regulation of innate immune response

MGI:MGI:3697751
PMID:17187069[1]

IMP: Inferred from Mutant Phenotype

MGI:MGI:3698412

P

From MGI

GO:0045408

regulation of interleukin-6 biosynthetic process

MGI:MGI:3654747
PMID:16862125[2]

IMP: Inferred from Mutant Phenotype

MGI:MGI:3663486

P

From MGI

GO:0046330

positive regulation of JNK cascade

MGI:MGI:3697751
PMID:17187069[1]

IMP: Inferred from Mutant Phenotype

MGI:MGI:3698412

P

From MGI

GO:0046330

positive regulation of JNK cascade

MGI:MGI:3697751
PMID:17187069[1]

ISA: Inferred from Sequence Alignment

UniProtKB:Q9H257

P

From MGI

GO:0050700

CARD domain binding

MGI:MGI:4834177

ISO: Inferred from Sequence Orthology

UniProtKB:Q9H257

F

From MGI

GO:0050830

defense response to Gram-positive bacterium

MGI:MGI:3697751
PMID:17187069[1]

IMP: Inferred from Mutant Phenotype

MGI:MGI:3698412

P

From MGI

GO:0051607

defense response to virus

MGI:MGI:3697751
PMID:17187069[1]

IMP: Inferred from Mutant Phenotype

MGI:MGI:3698412

P

From MGI

NOT

GO:0051092

positive regulation of NF-kappaB transcription factor activity

MGI:MGI:3697751
PMID:17187069[1]

IMP: Inferred from Mutant Phenotype

MGI:MGI:3698412

P

From MGI


Notes

References

See Help:References for how to manage references in GONUTS.
  1. 1.00 1.01 1.02 1.03 1.04 1.05 1.06 1.07 1.08 1.09 1.10 1.11 1.12 1.13 1.14 Hsu YM et al. (2007) The adaptor protein CARD9 is required for innate immune responses to intracellular pathogens. Nat Immunol 8: 198-205 PubMed GONUTS page
  2. 2.0 2.1 2.2 2.3 Gross O et al. (2006) Card9 controls a non-TLR signalling pathway for innate anti-fungal immunity. Nature 442: 651-6 PubMed GONUTS page
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