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MGI:Camk1

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Contents

Species (Taxon ID) Mus musculus (house mouse) (taxon:10090)
Gene Name(s) Camk1 ( synonyms: CaMKIalpha, D6Ertd263e )
Protein Name(s) calcium/calmodulin-dependent protein kinase I,
External Links
MGI MGI:1098535

Annotations

Qualifier GO ID GO term name Reference Evidence Code with/from Aspect Notes Status
GO:0000166

nucleotide binding

MGI:MGI:1354194

IEA: Inferred from Electronic Annotation

UniProtKB-KW:KW-0547

F

From MGI

GO:0003824

catalytic activity

MGI:MGI:1354194

IEA: Inferred from Electronic Annotation

UniProtKB-KW:KW-0021

F

From MGI

GO:0004672

protein kinase activity

MGI:MGI:2152098

IEA: Inferred from Electronic Annotation

InterPro:IPR000719
InterPro:IPR002290

F

From MGI

GO:0004674

protein serine/threonine kinase activity

MGI:MGI:1354194

IEA: Inferred from Electronic Annotation

UniProtKB-KW:KW-0723

F

From MGI

GO:0004674

protein serine/threonine kinase activity

MGI:MGI:2152098

IEA: Inferred from Electronic Annotation

InterPro:IPR008271

F

From MGI

GO:0004683

calmodulin-dependent protein kinase activity

MGI:MGI:4417868

ISO: Inferred from Sequence Orthology

UniProtKB:Q63450

F

From MGI

GO:0005515

protein binding

MGI:MGI:3510481
PMID:15284227[1]

IPI: Inferred from Physical Interaction

UniProtKB:Q9DBB1

F

From MGI

GO:0005516

calmodulin binding

MGI:MGI:1354194

IEA: Inferred from Electronic Annotation

UniProtKB-KW:KW-0112

F

From MGI

GO:0005524

ATP binding

MGI:MGI:1354194

IEA: Inferred from Electronic Annotation

UniProtKB-KW:KW-0067

F

From MGI

GO:0005524

ATP binding

MGI:MGI:2152098

IEA: Inferred from Electronic Annotation

InterPro:IPR000719
InterPro:IPR017441
InterPro:IPR002290

F

From MGI

GO:0005622

intracellular

MGI:MGI:2183076
PMID:12130539[2]

IDA: Inferred from Direct Assay

C

From MGI

GO:0005622

intracellular

MGI:MGI:3794928
PMID:18332106[3]

IDA: Inferred from Direct Assay

C

From MGI

GO:0005622

intracellular

MGI:MGI:3794928
PMID:18332106[3]

IGI: Inferred from Genetic Interaction

MGI:MGI:3036234

C

From MGI

GO:0005634

nucleus

MGI:MGI:1354194

IEA: Inferred from Electronic Annotation

UniProtKB-KW:KW-0539

C

From MGI

GO:0005737

cytoplasm

MGI:MGI:1354194

IEA: Inferred from Electronic Annotation

UniProtKB-KW:KW-0963

C

From MGI

GO:0005954

calcium- and calmodulin-dependent protein kinase complex

MGI:MGI:3688082
PMID:11264466[4]

TAS: Traceable Author Statement

C

From MGI

GO:0006468

protein phosphorylation

MGI:MGI:3794928
PMID:18332106[3]

IDA: Inferred from Direct Assay

P

From MGI

GO:0006468

protein phosphorylation

MGI:MGI:3794928
PMID:18332106[3]

IGI: Inferred from Genetic Interaction

MGI:MGI:3036234

P

From MGI

GO:0006468

protein phosphorylation

MGI:MGI:4834177

ISO: Inferred from Sequence Orthology

UniProtKB:Q14012

P

From MGI

GO:0006913

nucleocytoplasmic transport

MGI:MGI:2183076
PMID:12130539[2]

IDA: Inferred from Direct Assay

P

From MGI

GO:0006913

nucleocytoplasmic transport

MGI:MGI:3794928
PMID:18332106[3]

IDA: Inferred from Direct Assay

P

From MGI

GO:0006913

nucleocytoplasmic transport

MGI:MGI:3794928
PMID:18332106[3]

IGI: Inferred from Genetic Interaction

MGI:MGI:3036234

P

From MGI

GO:0007049

cell cycle

MGI:MGI:1354194

IEA: Inferred from Electronic Annotation

UniProtKB-KW:KW-0131

P

From MGI

GO:0007165

signal transduction

MGI:MGI:2183076
PMID:12130539[2]

IDA: Inferred from Direct Assay

P

From MGI

GO:0007275

multicellular organismal development

MGI:MGI:1354194

IEA: Inferred from Electronic Annotation

UniProtKB-KW:KW-0217

P

From MGI

GO:0007399

nervous system development

MGI:MGI:1354194

IEA: Inferred from Electronic Annotation

UniProtKB-KW:KW-0524

P

From MGI

GO:0008152

metabolic process

MGI:MGI:1354194

IEA: Inferred from Electronic Annotation

UniProtKB-KW:KW-0021

P

From MGI

GO:0010976

positive regulation of neuron projection development

MGI:MGI:4834177

ISO: Inferred from Sequence Orthology

UniProtKB:Q14012

P

From MGI

GO:0016301

kinase activity

MGI:MGI:1354194

IEA: Inferred from Electronic Annotation

UniProtKB-KW:KW-0418

F

From MGI

GO:0016310

phosphorylation

MGI:MGI:1354194

IEA: Inferred from Electronic Annotation

UniProtKB-KW:KW-0418

P

From MGI

GO:0016740

transferase activity

MGI:MGI:1354194

IEA: Inferred from Electronic Annotation

UniProtKB-KW:KW-0808

F

From MGI

GO:0016772

transferase activity, transferring phosphorus-containing groups

MGI:MGI:2152098

IEA: Inferred from Electronic Annotation

InterPro:IPR011009

F

From MGI

GO:0030154

cell differentiation

MGI:MGI:1354194

IEA: Inferred from Electronic Annotation

UniProtKB-KW:KW-0221

P

From MGI

GO:0032880

regulation of protein localization

MGI:MGI:4834177

ISO: Inferred from Sequence Orthology

UniProtKB:Q14012

P

From MGI

GO:0043393

regulation of protein binding

MGI:MGI:4834177

ISO: Inferred from Sequence Orthology

UniProtKB:Q14012

P

From MGI

GO:0046827

positive regulation of protein export from nucleus

MGI:MGI:4456961
PMID:11081517[5]

IDA: Inferred from Direct Assay

P

From MGI

GO:0051147

regulation of muscle cell differentiation

MGI:MGI:4834177

ISO: Inferred from Sequence Orthology

UniProtKB:Q14012

P

From MGI

GO:0051149

positive regulation of muscle cell differentiation

MGI:MGI:4834177

ISO: Inferred from Sequence Orthology

UniProtKB:Q14012

P

From MGI

GO:0051835

positive regulation of synapse structural plasticity

MGI:MGI:4834177

ISO: Inferred from Sequence Orthology

UniProtKB:Q14012

P

From MGI

GO:0060999

positive regulation of dendritic spine development

MGI:MGI:4834177

ISO: Inferred from Sequence Orthology

UniProtKB:Q14012

P

From MGI

GO:0071902

positive regulation of protein serine/threonine kinase activity

MGI:MGI:4834177

ISO: Inferred from Sequence Orthology

UniProtKB:Q14012

P

From MGI


Notes

References

See Help:References for how to manage references in GONUTS.
  1. Castelli M et al. (2004) MAP kinase phosphatase 3 (MKP3) interacts with and is phosphorylated by protein kinase CK2alpha. J Biol Chem 279: 44731-9 PubMed GONUTS page
  2. 2.0 2.1 2.2 Lazaro JB et al. (2002) Cyclin D-cdk4 activity modulates the subnuclear localization and interaction of MEF2 with SRC-family coactivators during skeletal muscle differentiation. Genes Dev 16: 1792-805 PubMed GONUTS page
  3. 3.0 3.1 3.2 3.3 3.4 3.5 Backs J et al. (2008) Histone deacetylase 5 acquires calcium/calmodulin-dependent kinase II responsiveness by oligomerization with histone deacetylase 4. Mol Cell Biol 28: 3437-45 PubMed GONUTS page
  4. Hook SS & Means AR (2001) Ca(2+)/CaM-dependent kinases: from activation to function. Annu Rev Pharmacol Toxicol 41: 471-505 PubMed GONUTS page
  5. McKinsey TA et al. (2000) Signal-dependent nuclear export of a histone deacetylase regulates muscle differentiation. Nature 408: 106-11 PubMed GONUTS page
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