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MGI:C5ar1

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Contents

Species (Taxon ID) Mus musculus (house mouse) (taxon:10090)
Gene Name(s) C5ar1 ( synonyms: C5aR, C5r1, Cd88, D7Msu1 )
Protein Name(s) complement component 5a receptor 1,
External Links
MGI MGI:88232

Annotations

Qualifier GO ID GO term name Reference Evidence Code with/from Aspect Notes Status
GO:0001856

complement component C5a binding

MGI:MGI:4417868

ISO: Inferred from Sequence Orthology

UniProtKB:P97520

F

From MGI

GO:0002430

complement receptor mediated signaling pathway

MGI:MGI:4417868

ISO: Inferred from Sequence Orthology

UniProtKB:P97520

P

From MGI

GO:0004871

signal transducer activity

MGI:MGI:1354194

IEA: Inferred from Electronic Annotation

UniProtKB-KW:KW-0807

F

From MGI

GO:0004872

receptor activity

MGI:MGI:1354194

IEA: Inferred from Electronic Annotation

UniProtKB-KW:KW-0675

F

From MGI

GO:0004878

complement component C5a receptor activity

MGI:MGI:4417868

ISO: Inferred from Sequence Orthology

UniProtKB:P97520

F

From MGI

GO:0004930

G-protein coupled receptor activity

MGI:MGI:1354194

IEA: Inferred from Electronic Annotation

UniProtKB-KW:KW-0297

F

From MGI

GO:0004944

C5a anaphylatoxin receptor activity

MGI:MGI:4417868

ISO: Inferred from Sequence Orthology

UniProtKB:P97520

F

From MGI

GO:0004944

C5a anaphylatoxin receptor activity

MGI:MGI:51391
PMID:1401897[1]

IDA: Inferred from Direct Assay

F

From MGI

GO:0005886

plasma membrane

MGI:MGI:4417868

ISO: Inferred from Sequence Orthology

UniProtKB:P97520

C

From MGI

GO:0006915

apoptotic process

MGI:MGI:4417868

ISO: Inferred from Sequence Orthology

UniProtKB:P97520

P

From MGI

GO:0007165

signal transduction

MGI:MGI:1354194

IEA: Inferred from Electronic Annotation

UniProtKB-KW:KW-0807

P

From MGI

GO:0007186

G-protein coupled receptor signaling pathway

MGI:MGI:1354194

IEA: Inferred from Electronic Annotation

UniProtKB-KW:KW-0297

P

From MGI

GO:0007186

G-protein coupled receptor signaling pathway

MGI:MGI:4417868

ISO: Inferred from Sequence Orthology

UniProtKB:P97520

P

From MGI

GO:0007204

elevation of cytosolic calcium ion concentration

MGI:MGI:4417868

ISO: Inferred from Sequence Orthology

UniProtKB:P97520

P

From MGI

GO:0009986

cell surface

MGI:MGI:4417868

ISO: Inferred from Sequence Orthology

UniProtKB:P97520

C

From MGI

GO:0016021

integral to membrane

MGI:MGI:1354194

IEA: Inferred from Electronic Annotation

UniProtKB-KW:KW-0812

C

From MGI

GO:0021534

cell proliferation in hindbrain

MGI:MGI:4417868

ISO: Inferred from Sequence Orthology

UniProtKB:P97520

P

From MGI

GO:0030593

neutrophil chemotaxis

MGI:MGI:3814295
PMID:17114491[2]

IMP: Inferred from Mutant Phenotype

MGI:MGI:1934246

P

From MGI

GO:0032494

response to peptidoglycan

MGI:MGI:3814295
PMID:17114491[2]

IMP: Inferred from Mutant Phenotype

MGI:MGI:1934246

P

From MGI

GO:0043524

negative regulation of neuron apoptotic process

MGI:MGI:4417868

ISO: Inferred from Sequence Orthology

UniProtKB:P97520

P

From MGI

GO:0043526

neuroprotection

MGI:MGI:4417868

ISO: Inferred from Sequence Orthology

UniProtKB:P97520

P

From MGI

GO:0050830

defense response to Gram-positive bacterium

MGI:MGI:3814295
PMID:17114491[2]

IMP: Inferred from Mutant Phenotype

P

From MGI


Notes

References

See Help:References for how to manage references in GONUTS.
  1. Gerard C et al. (1992) Structural diversity in the extracellular faces of peptidergic G-protein-coupled receptors. Molecular cloning of the mouse C5a anaphylatoxin receptor. J Immunol 149: 2600-6 PubMed GONUTS page
  2. 2.0 2.1 2.2 Mullaly SC & Kubes P (2006) The role of TLR2 in vivo following challenge with Staphylococcus aureus and prototypic ligands. J Immunol 177: 8154-63 PubMed GONUTS page
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