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MGI:Bub1b

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Contents

Species (Taxon ID) Mus musculus (house mouse) (taxon:10090)
Gene Name(s) Bub1b ( synonyms: BUBR1 )
Protein Name(s) budding uninhibited by benzimidazoles 1 homolog, beta (S. cerevisiae),
External Links
MGI MGI:1333889

Annotations

Qualifier GO ID GO term name Reference Evidence Code with/from Aspect Notes Status
GO:0000166

nucleotide binding

MGI:MGI:1354194

IEA: Inferred from Electronic Annotation

UniProtKB-KW:KW-0547

F

From MGI

GO:0000775

chromosome, centromeric region

MGI:MGI:1354194

IEA: Inferred from Electronic Annotation

UniProtKB-KW:KW-0137

C

From MGI

GO:0000776

kinetochore

MGI:MGI:2154458

ISO: Inferred from Sequence Orthology

UniProtKB:O60566

C

From MGI

GO:0000776

kinetochore

MGI:MGI:2154458

ISO: Inferred from Sequence Orthology

UniProtKB:O60566

C

From MGI

GO:0000776

kinetochore

MGI:MGI:2673075
PMID:12925705[1]

IDA: Inferred from Direct Assay

C

From MGI

GO:0000776

kinetochore

MGI:MGI:3047042
PMID:15226446[2]

IDA: Inferred from Direct Assay

C

From MGI

GO:0000776

kinetochore

MGI:MGI:3701148
PMID:17227893[3]

IMP: Inferred from Mutant Phenotype

C

From MGI

GO:0000777

condensed chromosome kinetochore

MGI:MGI:4834177

ISO: Inferred from Sequence Orthology

UniProtKB:O60566

C

From MGI

GO:0000940

condensed chromosome outer kinetochore

MGI:MGI:2682084
PMID:14519686[4]

IDA: Inferred from Direct Assay

C

From MGI

GO:0000940

condensed chromosome outer kinetochore

MGI:MGI:4834177

ISO: Inferred from Sequence Orthology

UniProtKB:O60566

C

From MGI

GO:0004672

protein kinase activity

MGI:MGI:2152098

IEA: Inferred from Electronic Annotation

InterPro:IPR000719

F

From MGI

GO:0004674

protein serine/threonine kinase activity

MGI:MGI:1354194

IEA: Inferred from Electronic Annotation

UniProtKB-KW:KW-0723

F

From MGI

GO:0005524

ATP binding

MGI:MGI:1354194

IEA: Inferred from Electronic Annotation

UniProtKB-KW:KW-0067

F

From MGI

GO:0005524

ATP binding

MGI:MGI:2152098

IEA: Inferred from Electronic Annotation

InterPro:IPR000719

F

From MGI

GO:0005634

nucleus

MGI:MGI:1354194

IEA: Inferred from Electronic Annotation

UniProtKB-KW:KW-0539

C

From MGI

GO:0005694

chromosome

MGI:MGI:1354194

IEA: Inferred from Electronic Annotation

UniProtKB-KW:KW-0158

C

From MGI

GO:0005737

cytoplasm

MGI:MGI:4834177

ISO: Inferred from Sequence Orthology

UniProtKB:O60566

C

From MGI

GO:0006468

protein phosphorylation

MGI:MGI:2152098

IEA: Inferred from Electronic Annotation

InterPro:IPR000719

P

From MGI

GO:0006915

apoptotic process

MGI:MGI:1354194

IEA: Inferred from Electronic Annotation

UniProtKB-KW:KW-0053

P

From MGI

GO:0007049

cell cycle

MGI:MGI:1354194

IEA: Inferred from Electronic Annotation

UniProtKB-KW:KW-0131

P

From MGI

GO:0007067

mitosis

MGI:MGI:1354194

IEA: Inferred from Electronic Annotation

UniProtKB-KW:KW-0498

P

From MGI

GO:0007091

mitotic metaphase/anaphase transition

MGI:MGI:3574170
PMID:15767571[5]

IGI: Inferred from Genetic Interaction

MGI:MGI:88039

P

From MGI

GO:0016301

kinase activity

MGI:MGI:1354194

IEA: Inferred from Electronic Annotation

UniProtKB-KW:KW-0418

F

From MGI

GO:0016310

phosphorylation

MGI:MGI:1354194

IEA: Inferred from Electronic Annotation

UniProtKB-KW:KW-0418

P

From MGI

GO:0016740

transferase activity

MGI:MGI:1354194

IEA: Inferred from Electronic Annotation

UniProtKB-KW:KW-0808

F

From MGI

GO:0016772

transferase activity, transferring phosphorus-containing groups

MGI:MGI:2152098

IEA: Inferred from Electronic Annotation

InterPro:IPR011009

F

From MGI

GO:0034501

protein localization to kinetochore

MGI:MGI:4834177

ISO: Inferred from Sequence Orthology

UniProtKB:O60566

P

From MGI

GO:0048471

perinuclear region of cytoplasm

MGI:MGI:4834177

ISO: Inferred from Sequence Orthology

UniProtKB:O60566

C

From MGI

GO:0051301

cell division

MGI:MGI:1354194

IEA: Inferred from Electronic Annotation

UniProtKB-KW:KW-0132

P

From MGI


Notes

References

See Help:References for how to manage references in GONUTS.
  1. Weaver BA et al. (2003) Centromere-associated protein-E is essential for the mammalian mitotic checkpoint to prevent aneuploidy due to single chromosome loss. J Cell Biol 162: 551-63 PubMed GONUTS page
  2. Le Cam L et al. (2004) The E4F protein is required for mitotic progression during embryonic cell cycles. Mol Cell Biol 24: 6467-75 PubMed GONUTS page
  3. Dikovskaya D et al. (2007) Loss of APC induces polyploidy as a result of a combination of defects in mitosis and apoptosis. J Cell Biol 176: 183-95 PubMed GONUTS page
  4. Craig JM et al. (2003) Analysis of mammalian proteins involved in chromatin modification reveals new metaphase centromeric proteins and distinct chromosomal distribution patterns. Hum Mol Genet 12: 3109-21 PubMed GONUTS page
  5. Rao CV et al. (2005) Colonic tumorigenesis in BubR1+/-ApcMin/+ compound mutant mice is linked to premature separation of sister chromatids and enhanced genomic instability. Proc Natl Acad Sci U S A 102: 4365-70 PubMed GONUTS page
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