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MGI:Btg2

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Contents

Species (Taxon ID) Mus musculus (house mouse) (taxon:10090)
Gene Name(s) Btg2 ( synonyms: APRO1, Pc3, TIS21 )
Protein Name(s) B cell translocation gene 2, anti-proliferative,
External Links
MGI MGI:108384

Annotations

Qualifier GO ID GO term name Reference Evidence Code with/from Aspect Notes Status
GO:0001077

RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription

MGI:MGI:2154458

ISO: Inferred from Sequence Orthology

UniProtKB:P27049

F

From MGI

GO:0005515

protein binding

MGI:MGI:3525050
PMID:15542835[1]

IPI: Inferred from Physical Interaction

UniProtKB:P70340
UniProtKB:Q9JIW5

F

From MGI

GO:0005515

protein binding

MGI:MGI:81228
PMID:8663146[2]

IPI: Inferred from Physical Interaction

UniProtKB:Q9EP80
UniProtKB:Q63009

F

From MGI

GO:0006351

transcription, DNA-dependent

MGI:MGI:1354194

IEA: Inferred from Electronic Annotation

UniProtKB-KW:KW-0804

P

From MGI

GO:0006355

regulation of transcription, DNA-dependent

MGI:MGI:1354194

IEA: Inferred from Electronic Annotation

UniProtKB-KW:KW-0805

P

From MGI

GO:0006479

protein methylation

MGI:MGI:81228
PMID:8663146[2]

IDA: Inferred from Direct Assay

P

From MGI

GO:0006974

response to DNA damage stimulus

MGI:MGI:2154458

ISO: Inferred from Sequence Orthology

UniProtKB:P78543

P

From MGI

GO:0008306

associative learning

MGI:MGI:4418391
PMID:20020054[3]

IMP: Inferred from Mutant Phenotype

MGI:MGI:3525505

P

From MGI

GO:0009952

anterior/posterior pattern specification

MGI:MGI:3525050
PMID:15542835[1]

IMP: Inferred from Mutant Phenotype

MGI:MGI:3525505

P

From MGI

GO:0021542

dentate gyrus development

MGI:MGI:4418391
PMID:20020054[3]

IMP: Inferred from Mutant Phenotype

MGI:MGI:3525505

P

From MGI

GO:0021954

central nervous system neuron development

MGI:MGI:4418391
PMID:20020054[3]

IMP: Inferred from Mutant Phenotype

MGI:MGI:3525505

P

From MGI

GO:0030182

neuron differentiation

MGI:MGI:2154458

ISO: Inferred from Sequence Orthology

UniProtKB:P27049

P

From MGI

GO:0031175

neuron projection development

MGI:MGI:4834177

ISO: Inferred from Sequence Orthology

UniProtKB:P78543

P

From MGI

GO:0043066

negative regulation of apoptotic process

MGI:MGI:2154458

ISO: Inferred from Sequence Orthology

UniProtKB:P27049

P

From MGI

GO:0045768

positive regulation of anti-apoptosis

MGI:MGI:4417868

ISO: Inferred from Sequence Orthology

UniProtKB:P27049

P

From MGI

GO:0045944

positive regulation of transcription from RNA polymerase II promoter

MGI:MGI:2154458

ISO: Inferred from Sequence Orthology

UniProtKB:P27049

P

From MGI

GO:0060213

positive regulation of nuclear-transcribed mRNA poly(A) tail shortening

MGI:MGI:2154458

ISO: Inferred from Sequence Orthology

UniProtKB:P78543

P

From MGI

GO:2000178

negative regulation of neural precursor cell proliferation

MGI:MGI:4418391
PMID:20020054[3]

IMP: Inferred from Mutant Phenotype

MGI:MGI:3525505

P

From MGI


Notes

References

See Help:References for how to manage references in GONUTS.
  1. 1.0 1.1 Park S et al. (2004) B-cell translocation gene 2 (Btg2) regulates vertebral patterning by modulating bone morphogenetic protein/smad signaling. Mol Cell Biol 24: 10256-62 PubMed GONUTS page
  2. 2.0 2.1 Lin WJ et al. (1996) The mammalian immediate-early TIS21 protein and the leukemia-associated BTG1 protein interact with a protein-arginine N-methyltransferase. J Biol Chem 271: 15034-44 PubMed GONUTS page
  3. 3.0 3.1 3.2 3.3 Farioli-Vecchioli S et al. (2009) Impaired terminal differentiation of hippocampal granule neurons and defective contextual memory in PC3/Tis21 knockout mice. PLoS One 4: e8339 PubMed GONUTS page
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