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MGI:Brsk2

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Contents

Species (Taxon ID) Mus musculus (house mouse) (taxon:10090)
Gene Name(s) Brsk2 ( synonyms: SAD-A )
Protein Name(s) BR serine/threonine kinase 2,
External Links
MGI MGI:1923020

Annotations

Qualifier GO ID GO term name Reference Evidence Code with/from Aspect Notes Status
GO:0000166

nucleotide binding

MGI:MGI:1354194

IEA: Inferred from Electronic Annotation

UniProtKB-KW:KW-0547

F

From MGI

GO:0000287

magnesium ion binding

MGI:MGI:3528781
PMID:15705853[1]

IC: Inferred by Curator

GO:0004674

F

From MGI

GO:0000287

magnesium ion binding

MGI:MGI:4834177

ISO: Inferred from Sequence Orthology

UniProtKB:Q8IWQ3

F

From MGI

GO:0004672

protein kinase activity

MGI:MGI:2152098

IEA: Inferred from Electronic Annotation

InterPro:IPR000719
InterPro:IPR002290

F

From MGI

GO:0004674

protein serine/threonine kinase activity

MGI:MGI:3528781
PMID:15705853[1]

IDA: Inferred from Direct Assay

F

From MGI

GO:0004674

protein serine/threonine kinase activity

MGI:MGI:4421246
PMID:20026642[2]

IDA: Inferred from Direct Assay

F

From MGI

GO:0004674

protein serine/threonine kinase activity

MGI:MGI:4834177

ISO: Inferred from Sequence Orthology

UniProtKB:Q8IWQ3

F

From MGI

GO:0005515

protein binding

MGI:MGI:4421246
PMID:20026642[2]

IPI: Inferred from Physical Interaction

UniProtKB:P47810
UniProtKB:Q5RJI5

F

From MGI

GO:0005524

ATP binding

MGI:MGI:4834177

ISO: Inferred from Sequence Orthology

UniProtKB:Q8IWQ3

F

From MGI

GO:0006468

protein phosphorylation

MGI:MGI:3528781
PMID:15705853[1]

IDA: Inferred from Direct Assay

P

From MGI

GO:0006468

protein phosphorylation

MGI:MGI:4462353
PMID:17482548[3]

TAS: Traceable Author Statement

P

From MGI

GO:0006468

protein phosphorylation

MGI:MGI:4834177

ISO: Inferred from Sequence Orthology

UniProtKB:Q8IWQ3

P

From MGI

GO:0007399

nervous system development

MGI:MGI:1354194

IEA: Inferred from Electronic Annotation

UniProtKB-KW:KW-0524

P

From MGI

GO:0007409

axonogenesis

MGI:MGI:4462353
PMID:17482548[3]

IMP: Inferred from Mutant Phenotype

P

From MGI

GO:0016301

kinase activity

MGI:MGI:1354194

IEA: Inferred from Electronic Annotation

UniProtKB-KW:KW-0418

F

From MGI

GO:0016310

phosphorylation

MGI:MGI:1354194

IEA: Inferred from Electronic Annotation

UniProtKB-KW:KW-0418

P

From MGI

GO:0016740

transferase activity

MGI:MGI:1354194

IEA: Inferred from Electronic Annotation

UniProtKB-KW:KW-0808

F

From MGI

GO:0016772

transferase activity, transferring phosphorus-containing groups

MGI:MGI:2152098

IEA: Inferred from Electronic Annotation

InterPro:IPR011009

F

From MGI

GO:0018105

peptidyl-serine phosphorylation

MGI:MGI:4421246
PMID:20026642[2]

IDA: Inferred from Direct Assay

P

From MGI

GO:0019901

protein kinase binding

MGI:MGI:4462353
PMID:17482548[3]

IPI: Inferred from Physical Interaction

UniProtKB:Q9WTK7

F

From MGI

GO:0030010

establishment of cell polarity

MGI:MGI:3528781
PMID:15705853[1]

IGI: Inferred from Genetic Interaction

MGI:MGI:2685946

P

From MGI

GO:0030010

establishment of cell polarity

MGI:MGI:4462353
PMID:17482548[3]

IMP: Inferred from Mutant Phenotype

P

From MGI

GO:0030182

neuron differentiation

MGI:MGI:3528781
PMID:15705853[1]

IGI: Inferred from Genetic Interaction

MGI:MGI:2685946

P

From MGI

GO:0046872

metal ion binding

MGI:MGI:1354194

IEA: Inferred from Electronic Annotation

UniProtKB-KW:KW-0479

F

From MGI

GO:0048812

neuron projection morphogenesis

MGI:MGI:4421246
PMID:20026642[2]

IGI: Inferred from Genetic Interaction

MGI:MGI:2685946
MGI:MGI:103075

P

From MGI

GO:0050321

tau-protein kinase activity

MGI:MGI:3528781
PMID:15705853[1]

IDA: Inferred from Direct Assay

F

From MGI

GO:0050321

tau-protein kinase activity

MGI:MGI:4462353
PMID:17482548[3]

TAS: Traceable Author Statement

F

From MGI


Notes

References

See Help:References for how to manage references in GONUTS.
  1. 1.0 1.1 1.2 1.3 1.4 1.5 Kishi M et al. (2005) Mammalian SAD kinases are required for neuronal polarization. Science 307: 929-32 PubMed GONUTS page
  2. 2.0 2.1 2.2 2.3 Müller M et al. (2010) Persistence of the cell-cycle checkpoint kinase Wee1 in SadA- and SadB-deficient neurons disrupts neuronal polarity. J Cell Sci 123: 286-94 PubMed GONUTS page
  3. 3.0 3.1 3.2 3.3 3.4 Barnes AP et al. (2007) LKB1 and SAD kinases define a pathway required for the polarization of cortical neurons. Cell 129: 549-63 PubMed GONUTS page
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