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MGI:Bnip3
Contents |
| Species (Taxon ID) | Mus musculus (house mouse) (taxon:10090) | |
| Gene Name(s) | Bnip3 ( synonyms: Nip3 ) | |
| Protein Name(s) | BCL2/adenovirus E1B interacting protein 3, | |
| External Links | ||
| MGI | MGI:109326 | |
Annotations
| Qualifier | GO ID | GO term name | Reference | Evidence Code | with/from | Aspect | Notes | Status |
|---|---|---|---|---|---|---|---|---|
| GO:0001666 |
response to hypoxia |
MGI:MGI:4417868 |
ISO: Inferred from Sequence Orthology |
NCBI:NP_445872 |
P |
From MGI |
||
| GO:0005515 |
protein binding |
MGI:MGI:1326944 |
IPI: Inferred from Physical Interaction |
F |
From MGI |
|||
| GO:0005634 |
nucleus |
MGI:MGI:4417868 |
ISO: Inferred from Sequence Orthology |
NCBI:NP_445872 |
C |
From MGI |
||
| GO:0005634 |
nucleus |
MGI:MGI:4834177 |
ISO: Inferred from Sequence Orthology |
C |
From MGI |
|||
| GO:0005635 |
nuclear envelope |
MGI:MGI:4834177 |
ISO: Inferred from Sequence Orthology |
C |
From MGI |
|||
| GO:0005654 |
nucleoplasm |
MGI:MGI:4417868 |
ISO: Inferred from Sequence Orthology |
NCBI:NP_445872 |
C |
From MGI |
||
| GO:0005737 |
cytoplasm |
MGI:MGI:4417868 |
ISO: Inferred from Sequence Orthology |
NCBI:NP_445872 |
C |
From MGI |
||
| GO:0005739 |
mitochondrion |
MGI:MGI:2154458 |
ISO: Inferred from Sequence Orthology |
C |
From MGI |
|||
| GO:0005739 |
mitochondrion |
MGI:MGI:2682130 |
IDA: Inferred from Direct Assay |
C |
From MGI |
|||
| GO:0005739 |
mitochondrion |
MGI:MGI:4834177 |
ISO: Inferred from Sequence Orthology |
C |
From MGI |
|||
| GO:0005740 |
mitochondrial envelope |
MGI:MGI:2152098 |
IEA: Inferred from Electronic Annotation |
C |
From MGI |
|||
| GO:0005741 |
mitochondrial outer membrane |
MGI:MGI:4834177 |
ISO: Inferred from Sequence Orthology |
C |
From MGI |
|||
| GO:0006309 |
DNA fragmentation involved in apoptotic nuclear change |
MGI:MGI:4834177 |
ISO: Inferred from Sequence Orthology |
P |
From MGI |
|||
| GO:0006338 |
chromatin remodeling |
MGI:MGI:4834177 |
ISO: Inferred from Sequence Orthology |
P |
From MGI |
|||
| GO:0006915 |
apoptotic process |
MGI:MGI:2665373 |
RCA: Inferred from Reviewed Computational Analysis |
P |
From MGI |
|||
| GO:0006915 |
apoptotic process |
MGI:MGI:4834177 |
ISO: Inferred from Sequence Orthology |
P |
From MGI |
|||
| GO:0006915 |
apoptotic process |
MGI:MGI:84904 |
ISO: Inferred from Sequence Orthology |
P |
From MGI |
|||
| GO:0006917 |
induction of apoptosis |
MGI:MGI:1326944 |
IDA: Inferred from Direct Assay |
P |
From MGI |
|||
| GO:0006917 |
induction of apoptosis |
MGI:MGI:3696331 |
IGI: Inferred from Genetic Interaction |
MGI:MGI:96224 |
P |
From MGI |
||
| GO:0006917 |
induction of apoptosis |
MGI:MGI:4834177 |
ISO: Inferred from Sequence Orthology |
P |
From MGI |
|||
| GO:0008219 |
cell death |
MGI:MGI:4417868 |
ISO: Inferred from Sequence Orthology |
NCBI:NP_445872 |
P |
From MGI |
||
| GO:0008219 |
cell death |
MGI:MGI:4834177 |
ISO: Inferred from Sequence Orthology |
P |
From MGI |
|||
| GO:0008629 |
induction of apoptosis by intracellular signals |
MGI:MGI:3696331 |
IMP: Inferred from Mutant Phenotype |
P |
From MGI |
|||
| GO:0008634 |
negative regulation of survival gene product expression |
MGI:MGI:4834177 |
ISO: Inferred from Sequence Orthology |
P |
From MGI |
|||
| GO:0010637 |
negative regulation of mitochondrial fusion |
MGI:MGI:4834177 |
ISO: Inferred from Sequence Orthology |
P |
From MGI |
|||
| GO:0016020 |
membrane |
MGI:MGI:1354194 |
IEA: Inferred from Electronic Annotation |
UniProtKB-KW:KW-0472 |
C |
From MGI |
||
| GO:0016021 |
integral to membrane |
MGI:MGI:1354194 |
IEA: Inferred from Electronic Annotation |
UniProtKB-KW:KW-0812 |
C |
From MGI |
||
| GO:0016021 |
integral to membrane |
MGI:MGI:2152098 |
IEA: Inferred from Electronic Annotation |
C |
From MGI |
|||
| GO:0030425 |
dendrite |
MGI:MGI:4417868 |
ISO: Inferred from Sequence Orthology |
NCBI:NP_445872 |
C |
From MGI |
||
| GO:0031307 |
integral to mitochondrial outer membrane |
MGI:MGI:4834177 |
ISO: Inferred from Sequence Orthology |
C |
From MGI |
|||
| GO:0031966 |
mitochondrial membrane |
MGI:MGI:3687820 |
IDA: Inferred from Direct Assay |
C |
From MGI |
|||
| GO:0031966 |
mitochondrial membrane |
MGI:MGI:4834177 |
ISO: Inferred from Sequence Orthology |
C |
From MGI |
|||
| GO:0035694 |
mitochondrial protein catabolic process |
MGI:MGI:4834177 |
ISO: Inferred from Sequence Orthology |
P |
From MGI |
|||
| GO:0042802 |
identical protein binding |
MGI:MGI:4834177 |
ISO: Inferred from Sequence Orthology |
F |
From MGI |
|||
| GO:0042803 |
protein homodimerization activity |
MGI:MGI:4834177 |
ISO: Inferred from Sequence Orthology |
F |
From MGI |
|||
| GO:0042981 |
regulation of apoptotic process |
MGI:MGI:2665373 |
RCA: Inferred from Reviewed Computational Analysis |
P |
From MGI |
|||
| GO:0043065 |
positive regulation of apoptotic process |
MGI:MGI:2152098 |
IEA: Inferred from Electronic Annotation |
P |
From MGI |
|||
| GO:0043243 |
positive regulation of protein complex disassembly |
MGI:MGI:4834177 |
ISO: Inferred from Sequence Orthology |
P |
From MGI |
|||
| GO:0043653 |
mitochondrial fragmentation involved in apoptosis |
MGI:MGI:4834177 |
ISO: Inferred from Sequence Orthology |
P |
From MGI |
|||
| GO:0045837 |
negative regulation of membrane potential |
MGI:MGI:4834177 |
ISO: Inferred from Sequence Orthology |
P |
From MGI |
|||
| GO:0046902 |
regulation of mitochondrial membrane permeability |
MGI:MGI:4834177 |
ISO: Inferred from Sequence Orthology |
P |
From MGI |
|||
| GO:0046982 |
protein heterodimerization activity |
MGI:MGI:4834177 |
ISO: Inferred from Sequence Orthology |
F |
From MGI |
|||
| GO:0048102 |
autophagic cell death |
MGI:MGI:4417868 |
ISO: Inferred from Sequence Orthology |
NCBI:NP_445872 |
P |
From MGI |
||
| GO:0050873 |
brown fat cell differentiation |
MGI:MGI:3801349 |
IDA: Inferred from Direct Assay |
P |
From MGI |
|||
| GO:0051020 |
GTPase binding |
MGI:MGI:4834177 |
ISO: Inferred from Sequence Orthology |
F |
From MGI |
|||
| GO:0051402 |
neuron apoptotic process |
MGI:MGI:4417868 |
ISO: Inferred from Sequence Orthology |
NCBI:NP_445872 |
P |
From MGI |
||
| GO:0051607 |
defense response to virus |
MGI:MGI:4834177 |
ISO: Inferred from Sequence Orthology |
P |
From MGI |
|||
| GO:0070301 |
cellular response to hydrogen peroxide |
MGI:MGI:4417868 |
ISO: Inferred from Sequence Orthology |
NCBI:NP_445872 |
P |
From MGI |
||
| GO:0071279 |
cellular response to cobalt ion |
MGI:MGI:4834177 |
ISO: Inferred from Sequence Orthology |
P |
From MGI |
|||
| GO:0071456 |
cellular response to hypoxia |
MGI:MGI:4834177 |
ISO: Inferred from Sequence Orthology |
P |
From MGI |
|||
| GO:0072593 |
reactive oxygen species metabolic process |
MGI:MGI:4834177 |
ISO: Inferred from Sequence Orthology |
P |
From MGI |
|||
| GO:0090141 |
positive regulation of mitochondrial fission |
MGI:MGI:4834177 |
ISO: Inferred from Sequence Orthology |
P |
From MGI |
|||
| GO:0090200 |
positive regulation of release of cytochrome c from mitochondria |
MGI:MGI:4834177 |
ISO: Inferred from Sequence Orthology |
P |
From MGI |
| ||
| edit table |
Notes
References
See Help:References for how to manage references in GONUTS.
- ↑ 1.0 1.1 Chen G et al. (1999) Nix and Nip3 form a subfamily of pro-apoptotic mitochondrial proteins. J Biol Chem 274: 7-10 PubMed GONUTS page
- ↑ Mootha VK et al. (2003) Integrated analysis of protein composition, tissue diversity, and gene regulation in mouse mitochondria. Cell 115: 629-40 PubMed GONUTS page
- ↑ 3.0 3.1 Reed JC et al. (2003) Comparative analysis of apoptosis and inflammation genes of mice and humans. Genome Res 13: 1376-88 PubMed GONUTS page
- ↑ Boyd JM et al. (1994) Adenovirus E1B 19 kDa and Bcl-2 proteins interact with a common set of cellular proteins. Cell 79: 341-51 PubMed GONUTS page
- ↑ 5.0 5.1 An HJ et al. (2006) Activation of Ras up-regulates pro-apoptotic BNIP3 in nitric oxide-induced cell death. J Biol Chem 281: 33939-48 PubMed GONUTS page
- ↑ Vande Velde C et al. (2000) BNIP3 and genetic control of necrosis-like cell death through the mitochondrial permeability transition pore. Mol Cell Biol 20: 5454-68 PubMed GONUTS page
- ↑ Wu Y & Smas CM (2008) Wdnm1-like, a new adipokine with a role in MMP-2 activation. Am J Physiol Endocrinol Metab 295: E205-15 PubMed GONUTS page
