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MGI:Bmpr1b
Contents |
| Species (Taxon ID) | Mus musculus (house mouse) (taxon:10090) | |
| Gene Name(s) | Bmpr1b ( synonyms: Acvrlk6, Alk6, BMPR-IB, CFK-43a ) | |
| Protein Name(s) | bone morphogenetic protein receptor, type 1B, | |
| External Links | ||
| MGI | MGI:107191 | |
Annotations
| Qualifier | GO ID | GO term name | Reference | Evidence Code | with/from | Aspect | Notes | Status |
|---|---|---|---|---|---|---|---|---|
| GO:0000166 |
nucleotide binding |
MGI:MGI:1354194 |
IEA: Inferred from Electronic Annotation |
UniProtKB-KW:KW-0547 |
F |
From MGI |
||
| GO:0001501 |
skeletal system development |
MGI:MGI:4834177 |
ISO: Inferred from Sequence Orthology |
P |
From MGI |
|||
| GO:0001502 |
cartilage condensation |
MGI:MGI:1351297 |
IMP: Inferred from Mutant Phenotype |
MGI:MGI:2158498 |
P |
From MGI |
||
| GO:0001550 |
ovarian cumulus expansion |
MGI:MGI:2136692 |
IMP: Inferred from Mutant Phenotype |
P |
From MGI |
|||
| GO:0001654 |
eye development |
MGI:MGI:2181740 |
IMP: Inferred from Mutant Phenotype |
P |
From MGI |
|||
| GO:0004672 |
protein kinase activity |
MGI:MGI:2152098 |
IEA: Inferred from Electronic Annotation |
F |
From MGI |
|||
| GO:0004674 |
protein serine/threonine kinase activity |
MGI:MGI:4834177 |
ISO: Inferred from Sequence Orthology |
F |
From MGI |
|||
| GO:0004675 |
transmembrane receptor protein serine/threonine kinase activity |
MGI:MGI:4834177 |
ISO: Inferred from Sequence Orthology |
F |
From MGI |
|||
| GO:0004872 |
receptor activity |
MGI:MGI:1354194 |
IEA: Inferred from Electronic Annotation |
UniProtKB-KW:KW-0675 |
F |
From MGI |
||
| GO:0005024 |
transforming growth factor beta-activated receptor activity |
MGI:MGI:1351297 |
TAS: Traceable Author Statement |
F |
From MGI |
|||
| GO:0005025 |
transforming growth factor beta receptor activity, type I |
MGI:MGI:1935017 |
IMP: Inferred from Mutant Phenotype |
F |
From MGI |
|||
| GO:0005524 |
ATP binding |
MGI:MGI:4834177 |
ISO: Inferred from Sequence Orthology |
F |
From MGI |
|||
| GO:0006468 |
protein phosphorylation |
MGI:MGI:4834177 |
ISO: Inferred from Sequence Orthology |
P |
From MGI |
|||
| GO:0006703 |
estrogen biosynthetic process |
MGI:MGI:2136692 |
NAS: Non-traceable Author Statement |
P |
From MGI |
|||
| GO:0007178 |
transmembrane receptor protein serine/threonine kinase signaling pathway |
MGI:MGI:4834177 |
ISO: Inferred from Sequence Orthology |
P |
From MGI |
|||
| GO:0007179 |
transforming growth factor beta receptor signaling pathway |
MGI:MGI:1351297 |
TAS: Traceable Author Statement |
P |
From MGI |
|||
| GO:0009953 |
dorsal/ventral pattern formation |
MGI:MGI:3574003 |
IGI: Inferred from Genetic Interaction |
MGI:MGI:1338938 |
P |
From MGI |
||
| GO:0016020 |
membrane |
MGI:MGI:1354194 |
IEA: Inferred from Electronic Annotation |
UniProtKB-KW:KW-0472 |
C |
From MGI |
||
| GO:0016020 |
membrane |
MGI:MGI:2152098 |
IEA: Inferred from Electronic Annotation |
C |
From MGI |
|||
| GO:0016021 |
integral to membrane |
MGI:MGI:1354194 |
IEA: Inferred from Electronic Annotation |
UniProtKB-KW:KW-0812 |
C |
From MGI |
||
| GO:0016301 |
kinase activity |
MGI:MGI:1354194 |
IEA: Inferred from Electronic Annotation |
UniProtKB-KW:KW-0418 |
F |
From MGI |
||
| GO:0016310 |
phosphorylation |
MGI:MGI:1354194 |
IEA: Inferred from Electronic Annotation |
UniProtKB-KW:KW-0418 |
P |
From MGI |
||
| GO:0016740 |
transferase activity |
MGI:MGI:1354194 |
IEA: Inferred from Electronic Annotation |
UniProtKB-KW:KW-0808 |
F |
From MGI |
||
| GO:0016772 |
transferase activity, transferring phosphorus-containing groups |
MGI:MGI:2152098 |
IEA: Inferred from Electronic Annotation |
F |
From MGI |
|||
| GO:0030154 |
cell differentiation |
MGI:MGI:2181740 |
IMP: Inferred from Mutant Phenotype |
P |
From MGI |
|||
| GO:0030154 |
cell differentiation |
MGI:MGI:3487205 |
IGI: Inferred from Genetic Interaction |
MGI:MGI:1338938 |
P |
From MGI |
||
| GO:0030425 |
dendrite |
MGI:MGI:4417868 |
ISO: Inferred from Sequence Orthology |
NCBI:NP_001019430 |
C |
From MGI |
||
| GO:0030501 |
positive regulation of bone mineralization |
MGI:MGI:4834177 |
ISO: Inferred from Sequence Orthology |
P |
From MGI |
|||
| GO:0030509 |
BMP signaling pathway |
MGI:MGI:1935017 |
IMP: Inferred from Mutant Phenotype |
P |
From MGI |
|||
| GO:0030509 |
BMP signaling pathway |
MGI:MGI:3604030 |
IGI: Inferred from Genetic Interaction |
MGI:MGI:95689 |
P |
From MGI |
||
| GO:0030509 |
BMP signaling pathway |
MGI:MGI:3625588 |
IGI: Inferred from Genetic Interaction |
MGI:MGI:109452 |
P |
From MGI |
||
| GO:0030509 |
BMP signaling pathway |
MGI:MGI:4834177 |
ISO: Inferred from Sequence Orthology |
P |
From MGI |
|||
| GO:0031290 |
retinal ganglion cell axon guidance |
MGI:MGI:2654391 |
IMP: Inferred from Mutant Phenotype |
MGI:MGI:2158497 |
P |
From MGI |
||
| GO:0035108 |
limb morphogenesis |
MGI:MGI:4834177 |
ISO: Inferred from Sequence Orthology |
P |
From MGI |
|||
| GO:0042698 |
ovulation cycle |
MGI:MGI:2136692 |
IMP: Inferred from Mutant Phenotype |
P |
From MGI |
|||
| GO:0043010 |
camera-type eye development |
MGI:MGI:3574003 |
IGI: Inferred from Genetic Interaction |
MGI:MGI:1338938 |
P |
From MGI |
||
| GO:0043025 |
neuronal cell body |
MGI:MGI:4417868 |
ISO: Inferred from Sequence Orthology |
NCBI:NP_001019430 |
C |
From MGI |
||
| GO:0045597 |
positive regulation of cell differentiation |
MGI:MGI:4834177 |
ISO: Inferred from Sequence Orthology |
P |
From MGI |
|||
| GO:0045669 |
positive regulation of osteoblast differentiation |
MGI:MGI:4834177 |
ISO: Inferred from Sequence Orthology |
P |
From MGI |
|||
| GO:0046332 |
SMAD binding |
MGI:MGI:4834177 |
ISO: Inferred from Sequence Orthology |
F |
From MGI |
|||
| GO:0046872 |
metal ion binding |
MGI:MGI:1354194 |
IEA: Inferred from Electronic Annotation |
UniProtKB-KW:KW-0479 |
F |
From MGI |
||
| GO:0051216 |
cartilage development |
MGI:MGI:1354194 |
IEA: Inferred from Electronic Annotation |
UniProtKB-KW:KW-0891 |
P |
From MGI |
||
| GO:0060041 |
retina development in camera-type eye |
MGI:MGI:2654391 |
IMP: Inferred from Mutant Phenotype |
MGI:MGI:2158497 |
P |
From MGI |
| |
| edit table |
Notes
References
See Help:References for how to manage references in GONUTS.
- ↑ 1.0 1.1 1.2 Baur ST et al. (2000) Combinatorial signaling through BMP receptor IB and GDF5: shaping of the distal mouse limb and the genetics of distal limb diversity. Development 127: 605-19 PubMed GONUTS page
- ↑ 2.0 2.1 2.2 Yi SE et al. (2001) The type I BMP receptor BmprIB is essential for female reproductive function. Proc Natl Acad Sci U S A 98: 7994-9 PubMed GONUTS page
- ↑ 3.0 3.1 Faber SC et al. (2002) Bmp signaling is required for development of primary lens fiber cells. Development 129: 3727-37 PubMed GONUTS page
- ↑ 4.0 4.1 Visser JA et al. (2001) The serine/threonine transmembrane receptor ALK2 mediates Müllerian inhibiting substance signaling. Mol Endocrinol 15: 936-45 PubMed GONUTS page
- ↑ 5.0 5.1 Murali D et al. (2005) Distinct developmental programs require different levels of Bmp signaling during mouse retinal development. Development 132: 913-23 PubMed GONUTS page
- ↑ Wine-Lee L et al. (2004) Signaling through BMP type 1 receptors is required for development of interneuron cell types in the dorsal spinal cord. Development 131: 5393-403 PubMed GONUTS page
- ↑ Mazerbourg S et al. (2005) Identification of receptors and signaling pathways for orphan bone morphogenetic protein/growth differentiation factor ligands based on genomic analyses. J Biol Chem 280: 32122-32 PubMed GONUTS page
- ↑ Babitt JL et al. (2006) Bone morphogenetic protein signaling by hemojuvelin regulates hepcidin expression. Nat Genet 38: 531-9 PubMed GONUTS page
- ↑ 9.0 9.1 Liu J et al. (2003) BMP receptor 1b is required for axon guidance and cell survival in the developing retina. Dev Biol 256: 34-48 PubMed GONUTS page
