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MGI:Bmf

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Contents

Species (Taxon ID) Mus musculus (house mouse) (taxon:10090)
Gene Name(s) Bmf
Protein Name(s) BCL2 modifying factor,
External Links
MGI MGI:2176433

Annotations

Qualifier GO ID GO term name Reference Evidence Code with/from Aspect Notes Status
GO:0001669

acrosomal vesicle

MGI:MGI:4417868

ISO: Inferred from Sequence Orthology

NCBI:NP_640351

C

From MGI

GO:0005515

protein binding

MGI:MGI:2158578
PMID:11546872[1]

IPI: Inferred from Physical Interaction

UniProtKB:Q9D0M5

F

From MGI

GO:0005515

protein binding

MGI:MGI:3689775
PMID:15694340[2]

IPI: Inferred from Physical Interaction

UniProtKB:P10415
UniProtKB:Q92843

F

From MGI

GO:0005515

protein binding

MGI:MGI:3694305
PMID:16697956[3]

IPI: Inferred from Physical Interaction

UniProtKB:P10415
UniProtKB:Q92843

F

From MGI

GO:0005737

cytoplasm

MGI:MGI:2158578
PMID:11546872[1]

IDA: Inferred from Direct Assay

C

From MGI

GO:0006915

apoptotic process

MGI:MGI:2158578
PMID:11546872[1]

IDA: Inferred from Direct Assay

P

From MGI

GO:0015629

actin cytoskeleton

MGI:MGI:2158578
PMID:11546872[1]

IDA: Inferred from Direct Assay

C

From MGI

GO:0016459

myosin complex

MGI:MGI:2158578
PMID:11546872[1]

IDA: Inferred from Direct Assay

C

From MGI

GO:0016459

myosin complex

MGI:MGI:2158578
PMID:11546872[1]

IPI: Inferred from Physical Interaction

UniProtKB:Q9D0M5

C

From MGI

GO:0032464

positive regulation of protein homooligomerization

MGI:MGI:5009775
PMID:21041309[4]

IDA: Inferred from Direct Assay

P

From MGI

GO:0042981

regulation of apoptotic process

MGI:MGI:2158578
PMID:11546872[1]

IDA: Inferred from Direct Assay

P

From MGI

GO:0090200

positive regulation of release of cytochrome c from mitochondria

MGI:MGI:5009775
PMID:21041309[4]

IGI: Inferred from Genetic Interaction

UniProtKB:P70444

P

From MGI


Notes

References

See Help:References for how to manage references in GONUTS.
  1. 1.0 1.1 1.2 1.3 1.4 1.5 1.6 Puthalakath H et al. (2001) Bmf: a proapoptotic BH3-only protein regulated by interaction with the myosin V actin motor complex, activated by anoikis. Science 293: 1829-32 PubMed GONUTS page
  2. Chen L et al. (2005) Differential targeting of prosurvival Bcl-2 proteins by their BH3-only ligands allows complementary apoptotic function. Mol Cell 17: 393-403 PubMed GONUTS page
  3. Certo M et al. (2006) Mitochondria primed by death signals determine cellular addiction to antiapoptotic BCL-2 family members. Cancer Cell 9: 351-65 PubMed GONUTS page
  4. 4.0 4.1 Du H et al. (2011) BH3 domains other than Bim and Bid can directly activate Bax/Bak. J Biol Chem 286: 491-501 PubMed GONUTS page
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