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MGI:Bik
Contents |
| Species (Taxon ID) | Mus musculus (house mouse) (taxon:10090) | |
| Gene Name(s) | Bik ( synonyms: Biklk, Blk, Nbk ) | |
| Protein Name(s) | BCL2-interacting killer, | |
| External Links | ||
| MGI | MGI:1206591 | |
Annotations
| Qualifier | GO ID | GO term name | Reference | Evidence Code | with/from | Aspect | Notes | Status |
|---|---|---|---|---|---|---|---|---|
| GO:0005515 |
protein binding |
MGI:MGI:1202139 |
IPI: Inferred from Physical Interaction |
F |
From MGI |
|||
| GO:0005740 |
mitochondrial envelope |
MGI:MGI:1202139 |
IDA: Inferred from Direct Assay |
C |
From MGI |
|||
| GO:0006917 |
induction of apoptosis |
MGI:MGI:1202139 |
IDA: Inferred from Direct Assay |
P |
From MGI |
|||
| GO:0007283 |
spermatogenesis |
MGI:MGI:3610512 |
IGI: Inferred from Genetic Interaction |
MGI:MGI:1197519 |
P |
From MGI |
||
| GO:0008584 |
male gonad development |
MGI:MGI:3610512 |
IGI: Inferred from Genetic Interaction |
MGI:MGI:1197519 |
P |
From MGI |
||
| GO:0032464 |
positive regulation of protein homooligomerization |
MGI:MGI:4834177 |
ISO: Inferred from Sequence Orthology |
P |
From MGI |
|||
| GO:0046982 |
protein heterodimerization activity |
MGI:MGI:4417868 |
ISO: Inferred from Sequence Orthology |
NCBI:NP_446156 |
F |
From MGI |
||
| GO:0051400 |
BH domain binding |
MGI:MGI:4417868 |
ISO: Inferred from Sequence Orthology |
NCBI:NP_446156 |
F |
From MGI |
||
| GO:0090200 |
positive regulation of release of cytochrome c from mitochondria |
MGI:MGI:4834177 |
ISO: Inferred from Sequence Orthology |
P |
From MGI |
| ||
| edit table |
Notes
References
See Help:References for how to manage references in GONUTS.
- ↑ 1.0 1.1 1.2 Hegde R et al. (1998) Blk, a BH3-containing mouse protein that interacts with Bcl-2 and Bcl-xL, is a potent death agonist. J Biol Chem 273: 7783-6 PubMed GONUTS page
- ↑ 2.0 2.1 Coultas L et al. (2005) Concomitant loss of proapoptotic BH3-only Bcl-2 antagonists Bik and Bim arrests spermatogenesis. EMBO J 24: 3963-73 PubMed GONUTS page
