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MGI:Bhlhb8

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Mus musculus (house mouse)

Bhlhb8:basic helix-loop-helix domain containing, class B, 8
Synonyms:Mist1
Bhlhb8 on MGI

GO terms

GO:0003677_!_DNA_binding (F) IDA [1]
GO:0003677_!_DNA_binding (F) ISO with/from UniProtKB:P70562 [2]
GO:0005515_!_protein_binding (F) ISO with/from UniProtKB:P70562 [2]
GO:0005634_!_nucleus (C) IDA [3]
GO:0005634_!_nucleus (C) IDA [4]
GO:0005634_!_nucleus (C) IDA [5]
GO:0005634_!_nucleus (C) ISO with/from UniProtKB:P70562 [2]
GO:0006350_!_transcription (P) IEA with/from SP_KW:KW-0804 [6]
GO:0006355_!_regulation_of_transcription,_DNA-dependent (P) TAS [2]
GO:0006851_!_mitochondrial_calcium_ion_transport (P) IMP with/from MGI:MGI:2182768 [7]
GO:0007030_!_Golgi_organization (P) IMP with/from MGI:MGI:2182768 [7]
GO:0007186_!_G-protein_coupled_receptor_protein_signaling_pathway (P) IDA [3]
GO:0007267_!_cell-cell_signaling (P) IMP with/from MGI:MGI:2182768 [8]
GO:0019722_!_calcium-mediated_signaling (P) IMP with/from MGI:MGI:2182768 [7]
GO:0030528_!_transcription_regulator_activity (F) IDA [8]
GO:0042593_!_glucose_homeostasis (P) IMP with/from MGI:MGI:2182768 [5]
GO:0042803_!_protein_homodimerization_activity (F) IPI with/from UniProtKB:Q9QYC3 [1]
GO:0045449_!_regulation_of_transcription (P) IEA with/from InterPro:IPR001092,InterPro:IPR011598 [9]
GO:0045944_!_positive_regulation_of_transcription_from_RNA_polymerase_II_promoter (P) IDA [8]
GO:0045944_!_positive_regulation_of_transcription_from_RNA_polymerase_II_promoter (P) IDA [1]
GO:0048312_!_intracellular_distribution_of_mitochondria (P) IMP with/from MGI:MGI:2182768 [7]
GO:0048469_!_cell_maturation (P) IMP [1]
GO:0048469_!_cell_maturation (P) IMP with/from MGI:MGI:2182768 [5]

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Notes

References

See Help:References for how to manage references in GONUTS.
  1. 1.0 1.1 1.2 1.3 Zhu L et al. (2004) Inhibition of Mist1 homodimer formation induces pancreatic acinar-to-ductal metaplasia. Mol Cell Biol 24: 2673-81 PubMed GONUTS page
  2. 2.0 2.1 2.2 2.3 Lemercier C et al. (1997) Mist1: a novel basic helix-loop-helix transcription factor exhibits a developmentally regulated expression pattern. Dev Biol 182: 101-13 PubMed GONUTS page
  3. 3.0 3.1 Pin CL et al. (2001) The bHLH transcription factor Mist1 is required to maintain exocrine pancreas cell organization and acinar cell identity. J Cell Biol 155: 519-30 PubMed GONUTS page
  4. Hald J et al. (2003) Activated Notch1 prevents differentiation of pancreatic acinar cells and attenuate endocrine development. Dev Biol 260: 426-37 PubMed GONUTS page
  5. 5.0 5.1 5.2 Fazio EN et al. (2005) Altered Glut-2 accumulation and beta-cell function in mice lacking the exocrine-specific transcription factor, Mist1. J Endocrinol 187: 407-18 PubMed GONUTS page
  6. MGI annotation MGI:1354194
  7. 7.0 7.1 7.2 7.3 Luo X et al. (2005) Aberrant localization of intracellular organelles, Ca2+ signaling, and exocytosis in Mist1 null mice. J Biol Chem 280: 12668-75 PubMed GONUTS page
  8. 8.0 8.1 8.2 Rukstalis JM et al. (2003) Exocrine specific expression of Connexin32 is dependent on the basic helix-loop-helix transcription factor Mist1. J Cell Sci 116: 3315-25 PubMed GONUTS page
  9. MGI annotation MGI:2152098
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