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MGI:Bhlha15
Contents |
| Species (Taxon ID) | Mus musculus (house mouse) (taxon:10090) | |
| Gene Name(s) | Bhlha15 ( synonyms: Bhlhb8, Mist1 ) | |
| Protein Name(s) | basic helix-loop-helix family, member a15, | |
| External Links | ||
| MGI | MGI:891976 | |
Annotations
| Qualifier | GO ID | GO term name | Reference | Evidence Code | with/from | Aspect | Notes | Status |
|---|---|---|---|---|---|---|---|---|
| GO:0003677 |
DNA binding |
MGI:MGI:3038031 |
IDA: Inferred from Direct Assay |
F |
From MGI |
|||
| GO:0003677 |
DNA binding |
MGI:MGI:4417868 |
ISO: Inferred from Sequence Orthology |
F |
From MGI |
|||
| GO:0003677 |
DNA binding |
MGI:MGI:86444 |
ISO: Inferred from Sequence Orthology |
F |
From MGI |
|||
| GO:0005622 |
intracellular |
MGI:MGI:3578701 |
IMP: Inferred from Mutant Phenotype |
MGI:MGI:2182768 |
C |
From MGI |
||
| GO:0005634 |
nucleus |
MGI:MGI:2153617 |
IDA: Inferred from Direct Assay |
C |
From MGI |
|||
| GO:0005634 |
nucleus |
MGI:MGI:2670558 |
IDA: Inferred from Direct Assay |
C |
From MGI |
|||
| GO:0005634 |
nucleus |
MGI:MGI:3611530 |
IDA: Inferred from Direct Assay |
C |
From MGI |
|||
| GO:0005634 |
nucleus |
MGI:MGI:86444 |
ISO: Inferred from Sequence Orthology |
C |
From MGI |
|||
| GO:0006351 |
transcription, DNA-dependent |
MGI:MGI:1354194 |
IEA: Inferred from Electronic Annotation |
UniProtKB-KW:KW-0804 |
P |
From MGI |
||
| GO:0006355 |
regulation of transcription, DNA-dependent |
MGI:MGI:86444 |
TAS: Traceable Author Statement |
P |
From MGI |
|||
| GO:0006851 |
mitochondrial calcium ion transport |
MGI:MGI:3578701 |
IMP: Inferred from Mutant Phenotype |
MGI:MGI:2182768 |
P |
From MGI |
||
| GO:0007030 |
Golgi organization |
MGI:MGI:3578701 |
IMP: Inferred from Mutant Phenotype |
MGI:MGI:2182768 |
P |
From MGI |
||
| GO:0007186 |
G-protein coupled receptor signaling pathway |
MGI:MGI:2153617 |
IDA: Inferred from Direct Assay |
P |
From MGI |
|||
| GO:0007267 |
cell-cell signaling |
MGI:MGI:2671736 |
IMP: Inferred from Mutant Phenotype |
MGI:MGI:2182768 |
P |
From MGI |
||
| GO:0019722 |
calcium-mediated signaling |
MGI:MGI:3578701 |
IMP: Inferred from Mutant Phenotype |
MGI:MGI:2182768 |
P |
From MGI |
||
| GO:0042593 |
glucose homeostasis |
MGI:MGI:3611530 |
IMP: Inferred from Mutant Phenotype |
MGI:MGI:2182768 |
P |
From MGI |
||
| GO:0042803 |
protein homodimerization activity |
MGI:MGI:3038031 |
IPI: Inferred from Physical Interaction |
F |
From MGI |
|||
| GO:0045944 |
positive regulation of transcription from RNA polymerase II promoter |
MGI:MGI:2671736 |
IDA: Inferred from Direct Assay |
P |
From MGI |
|||
| GO:0045944 |
positive regulation of transcription from RNA polymerase II promoter |
MGI:MGI:3038031 |
IDA: Inferred from Direct Assay |
P |
From MGI |
|||
| GO:0048312 |
intracellular distribution of mitochondria |
MGI:MGI:3578701 |
IMP: Inferred from Mutant Phenotype |
MGI:MGI:2182768 |
P |
From MGI |
||
| GO:0048469 |
cell maturation |
MGI:MGI:3038031 |
IMP: Inferred from Mutant Phenotype |
P |
From MGI |
|||
| GO:0048469 |
cell maturation |
MGI:MGI:3611530 |
IMP: Inferred from Mutant Phenotype |
MGI:MGI:2182768 |
P |
From MGI |
| |
| edit table |
Notes
References
See Help:References for how to manage references in GONUTS.
- ↑ 1.0 1.1 1.2 1.3 Zhu L et al. (2004) Inhibition of Mist1 homodimer formation induces pancreatic acinar-to-ductal metaplasia. Mol Cell Biol 24: 2673-81 PubMed GONUTS page
- ↑ 2.0 2.1 2.2 Lemercier C et al. (1997) Mist1: a novel basic helix-loop-helix transcription factor exhibits a developmentally regulated expression pattern. Dev Biol 182: 101-13 PubMed GONUTS page
- ↑ 3.0 3.1 3.2 3.3 3.4 Luo X et al. (2005) Aberrant localization of intracellular organelles, Ca2+ signaling, and exocytosis in Mist1 null mice. J Biol Chem 280: 12668-75 PubMed GONUTS page
- ↑ 4.0 4.1 Pin CL et al. (2001) The bHLH transcription factor Mist1 is required to maintain exocrine pancreas cell organization and acinar cell identity. J Cell Biol 155: 519-30 PubMed GONUTS page
- ↑ Hald J et al. (2003) Activated Notch1 prevents differentiation of pancreatic acinar cells and attenuate endocrine development. Dev Biol 260: 426-37 PubMed GONUTS page
- ↑ 6.0 6.1 6.2 Fazio EN et al. (2005) Altered Glut-2 accumulation and beta-cell function in mice lacking the exocrine-specific transcription factor, Mist1. J Endocrinol 187: 407-18 PubMed GONUTS page
- ↑ 7.0 7.1 Rukstalis JM et al. (2003) Exocrine specific expression of Connexin32 is dependent on the basic helix-loop-helix transcription factor Mist1. J Cell Sci 116: 3315-25 PubMed GONUTS page
