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MGI:Bcat2
Contents |
| Species (Taxon ID) | Mus musculus (house mouse) (taxon:10090) | |
| Gene Name(s) | Bcat2 ( synonyms: Bcat-2, Eca40 ) | |
| Protein Name(s) | branched chain aminotransferase 2, mitochondrial, | |
| External Links | ||
| MGI | MGI:1276534 | |
Annotations
| Qualifier | GO ID | GO term name | Reference | Evidence Code | with/from | Aspect | Notes | Status |
|---|---|---|---|---|---|---|---|---|
| GO:0003824 |
catalytic activity |
MGI:MGI:2152098 |
IEA: Inferred from Electronic Annotation |
F |
From MGI |
|||
| GO:0004084 |
branched-chain-amino-acid transaminase activity |
MGI:MGI:3027291 |
IDA: Inferred from Direct Assay |
F |
From MGI |
|||
| GO:0004084 |
branched-chain-amino-acid transaminase activity |
MGI:MGI:4417868 |
ISO: Inferred from Sequence Orthology |
F |
From MGI |
|||
| GO:0005634 |
nucleus |
MGI:MGI:4417868 |
ISO: Inferred from Sequence Orthology |
C |
From MGI |
|||
| GO:0005737 |
cytoplasm |
MGI:MGI:4417868 |
ISO: Inferred from Sequence Orthology |
C |
From MGI |
|||
| GO:0005739 |
mitochondrion |
MGI:MGI:2682130 |
IDA: Inferred from Direct Assay |
C |
From MGI |
|||
| GO:0005739 |
mitochondrion |
MGI:MGI:3027291 |
IDA: Inferred from Direct Assay |
C |
From MGI |
|||
| GO:0005739 |
mitochondrion |
MGI:MGI:3852644 |
IDA: Inferred from Direct Assay |
C |
From MGI |
|||
| GO:0005739 |
mitochondrion |
MGI:MGI:4417868 |
ISO: Inferred from Sequence Orthology |
C |
From MGI |
|||
| GO:0006549 |
isoleucine metabolic process |
MGI:MGI:3027291 |
IMP: Inferred from Mutant Phenotype |
MGI:MGI:3028726 |
P |
From MGI |
||
| GO:0006550 |
isoleucine catabolic process |
MGI:MGI:3770498 |
IMP: Inferred from Mutant Phenotype |
MGI:MGI:3772355 |
P |
From MGI |
||
| GO:0006550 |
isoleucine catabolic process |
MGI:MGI:4417868 |
ISO: Inferred from Sequence Orthology |
P |
From MGI |
|||
| GO:0006551 |
leucine metabolic process |
MGI:MGI:3027291 |
IMP: Inferred from Mutant Phenotype |
MGI:MGI:3028726 |
P |
From MGI |
||
| GO:0006551 |
leucine metabolic process |
MGI:MGI:3770498 |
IMP: Inferred from Mutant Phenotype |
MGI:MGI:3772355 |
P |
From MGI |
||
| GO:0006573 |
valine metabolic process |
MGI:MGI:3027291 |
IMP: Inferred from Mutant Phenotype |
MGI:MGI:3028726 |
P |
From MGI |
||
| GO:0006573 |
valine metabolic process |
MGI:MGI:3770498 |
IMP: Inferred from Mutant Phenotype |
MGI:MGI:3772355 |
P |
From MGI |
||
| GO:0008483 |
transaminase activity |
MGI:MGI:1354194 |
IEA: Inferred from Electronic Annotation |
UniProtKB-KW:KW-0032 |
F |
From MGI |
||
| GO:0008652 |
cellular amino acid biosynthetic process |
MGI:MGI:1354194 |
IEA: Inferred from Electronic Annotation |
UniProtKB-KW:KW-0028 |
P |
From MGI |
||
| GO:0009081 |
branched chain family amino acid metabolic process |
MGI:MGI:4442298 |
IMP: Inferred from Mutant Phenotype |
MGI:MGI:3772355 |
P |
From MGI |
||
| GO:0009082 |
branched chain family amino acid biosynthetic process |
MGI:MGI:1354194 |
IEA: Inferred from Electronic Annotation |
UniProtKB-KW:KW-0100 |
P |
From MGI |
||
| GO:0009083 |
branched chain family amino acid catabolic process |
MGI:MGI:3027291 |
IMP: Inferred from Mutant Phenotype |
MGI:MGI:3028726 |
P |
From MGI |
||
| GO:0009083 |
branched chain family amino acid catabolic process |
MGI:MGI:4417868 |
ISO: Inferred from Sequence Orthology |
P |
From MGI |
|||
| GO:0009098 |
leucine biosynthetic process |
MGI:MGI:4417868 |
ISO: Inferred from Sequence Orthology |
P |
From MGI |
|||
| GO:0010817 |
regulation of hormone levels |
MGI:MGI:3770498 |
IMP: Inferred from Mutant Phenotype |
MGI:MGI:3772355 |
P |
From MGI |
||
| GO:0016740 |
transferase activity |
MGI:MGI:1354194 |
IEA: Inferred from Electronic Annotation |
UniProtKB-KW:KW-0808 |
F |
From MGI |
||
| GO:0052654 |
L-leucine transaminase activity |
MGI:MGI:2152096 |
IEA: Inferred from Electronic Annotation |
F |
From MGI |
|||
| GO:0052655 |
L-valine transaminase activity |
MGI:MGI:2152096 |
IEA: Inferred from Electronic Annotation |
F |
From MGI |
|||
| GO:0052656 |
L-isoleucine transaminase activity |
MGI:MGI:2152096 |
IEA: Inferred from Electronic Annotation |
F |
From MGI |
| ||
| edit table |
Notes
References
See Help:References for how to manage references in GONUTS.
- ↑ 1.0 1.1 1.2 1.3 1.4 1.5 Wu JY et al. (2004) ENU mutagenesis identifies mice with mitochondrial branched-chain aminotransferase deficiency resembling human maple syrup urine disease. J Clin Invest 113: 434-40 PubMed GONUTS page
- ↑ Mootha VK et al. (2003) Integrated analysis of protein composition, tissue diversity, and gene regulation in mouse mitochondria. Cell 115: 629-40 PubMed GONUTS page
- ↑ Pagliarini DJ et al. (2008) A mitochondrial protein compendium elucidates complex I disease biology. Cell 134: 112-23 PubMed GONUTS page
- ↑ 4.0 4.1 4.2 4.3 She P et al. (2007) Disruption of BCATm in mice leads to increased energy expenditure associated with the activation of a futile protein turnover cycle. Cell Metab 6: 181-94 PubMed GONUTS page
- ↑ Lang CH et al. (2010) Alcohol-induced IGF-I resistance is ameliorated in mice deficient for mitochondrial branched-chain aminotransferase. J Nutr 140: 932-8 PubMed GONUTS page
